Ground state and edge excitations of quantum Hall liquid at filling factor 2/3

We present a numerical study of fractional quantum Hall liquid at Landau level filling factor $\nu=2/3$ in a microscopic model including long-range Coulomb interaction and edge confining potential, based on the disc geometry. We find the ground state is accurately described by the particle-hole conjugate of a $\nu=1/3$ Laughlin state. We also find there are two counter-propagating edge modes, and the velocity of the forward-propagating mode is larger than the backward-propagating mode. The velocities have opposite responses to the change of the background confinement potential. On the other hand changing the two-body Coulomb potential has qualitatively the same effect on the velocities; for example we find increasing layer thickness (which softens of the Coulomb interaction) reduces both the forward mode and the backward mode velocities.Comment: 12 pages, 13 figure

Entanglement distribution maximization over one-side Gaussian noisy channel

The optimization of entanglement evolution for two-mode Gaussian pure states under one-side Gaussian map is studied. Even there isn't complete information about the one-side Gaussian noisy channel, one can still maximize the entanglement distribution by testing the channel with only two specific states

The relation between Hardy's non-locality and violation of Bell inequality

We give a analytic quantitative relation between Hardy's non-locality and Bell operator. We find that Hardy's non-locality is a sufficient condition for violation of Bell inequality, the upper bound of Hardy's non-locality allowed by information causality just correspond to Tsirelson bound of Bell inequality, and the upper bound of Hardy's non-locality allowed by the principle of no-signaling just correspond to the algebraic maximum of Bell operator. Then we study the Cabello's argument of Hardy's non-locality (a generalization of Hardy's argument) and find a similar relation between it and violation of Bell inequality. Finally, we give a simple derivation of the bound of Hardy's non-locality under the constraint of information causality with the aid of above derived relation between Hardy's non-locality and Bell operator, this bound is the main result of a recent work of Ahanj \emph{et al.} [Phys. Rev. A {\bf81}, 032103(2010)].Comment: 4 pages, no figure, minor chang

Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells

Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens. To overcome these barriers, we reprogrammed tumor-immune cell cross-talk by combined use of decitabine and adoptive immunotherapy, containing tumor-sensitized T cells and CD25+ NKT cells. Decitabine functioned to induce the expression of highly immunogenic cancer testis antigens in the tumor, while also reducing the frequency of myeloid-derived suppressor cells and the presence of CD25+ NKT cells rendered T cells, resistant to remaining myeloid-derived suppressor cells. This combinatorial therapy significantly prolonged survival of animals bearing metastatic tumor cells. Adoptive immunotherapy also induced tumor immunoediting, resulting in tumor escape and associated disease-related mortality. To identify a tumor target that is incapable of escape from the immune response, we used dormant tumor cells. We used Adriamycin chemotherapy or radiation therapy, which simultaneously induce tumor cell death and tumor dormancy. Resultant dormant cells became refractory to additional doses of Adriamycin or radiation therapy, but they remained sensitive to tumor-reactive immune cells. Importantly, we discovered that dormant tumor cells contained indolent cells that expressed low levels of Ki67 and quiescent cells that were Ki67 negative. Whereas the former were prone to tumor immunoediting and escape, the latter did not demonstrate immunoediting. Our results suggest that immunotherapy could be highly effective against quiescent dormant tumor cells. The challenge is to develop combinatorial therapies that could establish a quiescent type of tumor dormancy, which would be the best target for immunotherapy

Sleep duration and patterns in Chinese older adults: A comprehensive meta-analysis

This meta-analysis examined the mean sleep duration and patterns in Chinese older adult population. A literature search was systematically conducted covering major English (PubMed, Embase and PsycINFO) and Chinese (Chinese National Knowledge Infrastructure (CNKI), WanFang and SinoMed) databases. Data in studies with the mean and standard deviation of sleep duration and/or the proportion of short and long sleep durations in Chinese older adults were extracted and pooled using random-effects models. Subgroup analyses were conducted according to gender, region, area, survey time and sample size. A total of 36 studies with 150,616 subjects were included for analyses. The pooled mean sleep duration of 21 studies with available data was 6.82 hours/day (95% CI: 6.59–7.05 hours/day). The estimated proportions of sleep duration \u3c5 hours/day, \u3c6 hours/day, \u3c7 hours/day were 18.8% (95% CI: 1.7%–35.9%), 26.7% (95% CI: 19.7%–33.7%) and 42.3% (95% CI: 34.8%–49.8%), respectively. The pooled proportions for long sleepers were 22.6% (95% CI: 13.9%–31.4%) (\u3e8 hours/day) and 17.6% (95% CI: 12.4%–22.9%) (\u3e9 hours/day). Given the adverse effects of unhealthy sleep patterns, health professionals should pay more attention to sleep patterns in this population in China

Virialization of Galaxy Clusters and Beyond

Using samples of structures identified by a multi-scale decomposition from numerical simulation, we analyze the scale-dependence of the virialization of clusters. We find that beyond the scale of full virialization there exists a radius range over which clusters are quasi-virialized, i.e. while the internal structure of an {\it individual} cluster is at substantial departure from dynamical relaxation, some {\it statistical} properties of the multi-scale identified clusters are approximately the same as those for the virialized systems. The dynamical reason of the existence of quasi-virialization is that some of the scaling properties of dynamically relaxed systems of cosmic gravitational clustering approximately hold beyond the full virialization regime. The "individual-statistical" duality of the quasi-virialization provides an explanation of the observed puzzle that the total masses of clusters derived from virial theorem are statistically the same as the gravitational lensing determined masses, in spite of the presence of irregular configuration and substructures in individual clusters. It also explains the tight correlation between the velocity dispersion of optical galaxies and the temperature of X-ray emitting gas. Consequently, the virial mass estimators based on the assumptions of isothermal and hydrostatic model are statistically applicable to scales on which the clusters are quasi-virialized. In the quasi-virialization regime, the temperature functions of clusters also show scaling. This feature is a useful discriminator among cosmological models.Comment: AAS Latex file, 22 pages+ 14 figures, accepted for publication in Ap

In vivo evolution of biopsy-proven inflammatory demyelination quantified by R2t* mapping

A 35-year-old man with an enhancing tumefactive brain lesion underwent biopsy, revealing inflammatory demyelination. We used quantitative Gradient-Recalled-Echo (qGRE) MRI to visualize and measure tissue damage in the lesion. Two weeks after biopsy, qGRE showed significant R2t* reduction in the left optic radiation and surrounding tissue, consistent with the histopathological and clinical findings. qGRE was repeated 6 and 14 months later, demonstrating partially recovered optic radiation R2t*, in concert with improvement of the hemianopia to ultimately involve only the lower right visual quadrant. These results support qGRE metrics as in vivo biomarkers for tissue damage and longitudinal monitoring of demyelinating disease

Relationship between a single bout of exhaustive exercise and endoplasmic reticulum stress in skeletal muscle

Nutrition & DieteticsSCI(E)0MEETING ABSTRACTOCE1E88-E887

Universal critical properties of the Eulerian bond-cubic model

We investigate the Eulerian bond-cubic model on the square lattice by means of Monte Carlo simulations, using an efficient cluster algorithm and a finite-size scaling analysis. The critical points and four critical exponents of the model are determined for several values of $n$. Two of the exponents are fractal dimensions, which are obtained numerically for the first time. Our results are consistent with the Coulomb gas predictions for the critical O($n$) branch for $n < 2$ and the results obtained by previous transfer matrix calculations. For $n=2$, we find that the thermal exponent, the magnetic exponent and the fractal dimension of the largest critical Eulerian bond component are different from those of the critical O(2) loop model. These results confirm that the cubic anisotropy is marginal at $n=2$ but irrelevant for $n<2$