20,067 research outputs found

    PeV-Scale Supersymmetry

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    Although supersymmetry has not been seen directly by experiment, there are powerful physics reasons to suspect that it should be an ingredient of nature and that superpartner masses should be somewhat near the weak scale. I present an argument that if we dismiss our ordinary intuition of finetuning, and focus entirely on more concrete physics issues, the PeV scale might be the best place for supersymmetry. PeV-scale supersymmetry admits gauge coupling unification, predicts a Higgs mass between 125 GeV and 155 GeV, and generally disallows flavor changing neutral currents and CP violating effects in conflict with current experiment. The PeV scale is motivated independently by dark matter and neutrino mass considerations.Comment: 5 RevTex page

    Implications of gauge-mediated supersymmetry breaking with vector-like quarks and a ~125 GeV Higgs boson

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    We investigate the implications of models that achieve a Standard Model-like Higgs boson of mass near 125 GeV by introducing additional TeV-scale supermultiplets in the vector-like 10+\bar{10} representation of SU(5), within the context of gauge-mediated supersymmetry breaking. We study the resulting mass spectrum of superpartners, comparing and contrasting to the usual gauge-mediated and CMSSM scenarios, and discuss implications for LHC supersymmetry searches. This approach implies that exotic vector-like fermions t'_{1,2}, b',and \tau' should be within the reach of the LHC. We discuss the masses, the couplings to electroweak bosons, and the decay branching ratios of the exotic fermions, with and without various unification assumptions for the mass and mixing parameters. We comment on LHC prospects for discovery of the exotic fermion states, both for decays that are prompt and non-prompt on detector-crossing time scales.Comment: 32 pages. v2: references added, figure caption 5.3 correcte

    The Dormancy Dilemma: Quiescence versus Balanced Proliferation

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    Metastatic dissemination with subsequent clinical outgrowth leads to the greatest part of morbidity and mortality from most solid tumors. Even more daunting is that many of these metastatic deposits silently lie undetected, recurring years to decades after primary tumor extirpation by surgery or radiation (termed metastatic dormancy). As primary tumors are frequently curable, a critical focus now turns to preventing the lethal emergence from metastatic dormancy. Current carcinoma treatments include adjuvant therapy intended to kill the cryptic metastatic tumor cells. Because such standard therapies mainly kill cycling cells, this approach carries an implicit assumption that metastatic cells are in the mitogenic cycle. Thus, the pivotal question arises as to whether clinically occult micrometastases survive in a state of balanced proliferation and death, or whether these cells undergo at least long periods of quiescence marked by cell-cycle arrest. The treatment implications are thus obvious—if the carcinoma cells are cycling then therapies should target cycling cells, whereas if cells are quiescent then therapies should either maintain dormancy or be toxic to dormant cells. Because this distinction is paramount to rational therapeutic development and administration, we investigated whether quiescence or balanced proliferation is the most likely etiology underlying metastatic dormancy. We recently published a computer simulation study that determined that balanced proliferation is not the likely driving force and that quiescence most likely participates in metastatic dormancy. As such, a greater emphasis on developing diagnostics and therapeutics for quiescent carcinomas is needed.National Institutes of Health (U.S.). National Center for Advancing Translational Sciences (Grant UH2TR000496

    Evaluation of a Mechanical System for Reconstructing Soil on Surface Mined Land

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    The existence of excessive soil compaction has hindered the surface mining industry from returning land to pre−mining productivity after reclamation, especially on prime farmland soils. Heavy earthmoving equipment used during reclamation tends to generate root−limiting bulk densities that adversely affect plant growth thereby decreasing yields. Therefore, the purpose of this study was to evaluate a mechanism, called the ‘Soil Regenerator,’ which reconstructs soil media at minimum bulk density during surface mine reclamation. The prototype soil forming mechanism was mounted on the front of a conventional bulldozer. Soil was placed in long narrow windrows by a scraper or bulldozer. As the bulldozer pushed into the windrow, soil rose up the blade and was agitated, transported, and deposited by a helicoid auger in a 0.9−m deep berm adjacent to the bulldozer. The capacity of the prototype ranged from 490 to 804 m3/h while producing bulk densities ≤ 1.0 Mg/m3 and penetrometer measurements below 0.7 MPa. These measurements demonstrated the capability of the ‘Soil Regenerator’ to eliminate soil compaction on reclaimed surface mined land and to reconstruct soil more suitable for crop growth

    Pulmonary vasospasm in systemic sclerosis: noninvasive techniques for detection

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    In a subgroup of patients with systemic sclerosis (SSc), vasospasm affecting the pulmonary circulation may contribute to worsening respiratory symptoms, including dyspnea. Noninvasive assessment of pulmonary blood flow (PBF), utilizing inert-gas rebreathing (IGR) and dual-energy computed-tomography pulmonary angiography (DE-CTPA), may be useful for identifying pulmonary vasospasm. Thirty-one participants (22 SSc patients and 9 healthy volunteers) underwent PBF assessment with IGR and DE-CTPA at baseline and after provocation with a cold-air inhalation challenge (CACh). Before the study investigations, participants were assigned to subgroups: group A included SSc patients who reported increased breathlessness after exposure to cold air (n = 11), group B included SSc patients without cold-air sensitivity (n = 11), and group C patients included the healthy volunteers. Median change in PBF from baseline was compared between groups A, B, and C after CACh. Compared with groups B and C, in group A there was a significant decline in median PBF from baseline at 10 minutes (−10%; range: −52.2% to 4.0%; P < 0.01), 20 minutes (−17.4%; −27.9% to 0.0%; P < 0.01), and 30 minutes (−8.5%; −34.4% to 2.0%; P < 0.01) after CACh. There was no significant difference in median PBF change between groups B or C at any time point and no change in pulmonary perfusion on DE-CTPA. Reduction in pulmonary blood flow following CACh suggests that pulmonary vasospasm may be present in a subgroup of patients with SSc and may contribute to worsening dyspnea on exposure to cold

    Research Notes: Interactions of cultural practices with insect-induced stress on soybeans

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    Numerous reports exist which characterize yield loss and defoliation relationships. Management guidelines and decisions regarding defoliating pests have been based largely upon findings from one or more of those studies . The use of such studies as decision-making criteria may be limited since most defoliation yield-related research has been conducted in the Midwest with varieties , growth habits and environmental conditions widely divergent from those found in other areas of production

    Effective-Hamiltonian parameters for \emph{ab initio} energy-level calculations of SrCl2_{2}:Yb2+^{2+} and CsCaBr3_{3}:Yb2+^{2+}

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    Calculated energy levels from recent \emph{ab initio} studies of the electronic structure of SrCl2_{2}:Yb2+^{2+} and CsCaBr3_{3}:Yb2+^{2+} are fitted with a semi-empirical "crystal-field" Hamiltonian, which acts within the model space 4f14+4f135d+4f136s4f^{14} + 4f^{13}5d + 4f^{13}6s. Parameters are obtained for the minima of the potential-energy curves for each energy level and also for a range of anion-cation separations. The parameters are compared with published results parameters fitted to experimental data and to atomic calculations. The states with significant 4f136s4f^{13}6s character give a good approximation of the impurity-trapped exciton states that appear in the \emph{ab initio} calculations.Comment: Minor revisio

    Coral Reef Fisheries Literature Review and Database Research Report, Final Technical Report

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    First, coral reef fisheries literature references were obtained and organised into a computer database and a user manual produced. Second, a comprehensive review article summarising and interpreting the disparate literature was written and distributed along with the database. The database and accompanying review should assist research and management of coral reef fisheries in developing countries. In the original project memorandum, it was stated that initial emphasis would be placed on fin-fish fisheries. This emphasis has been maintained throughout the projec
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