5,293 research outputs found
Pattern of skin disease in Ethiopian HIVâinfected patients on combination antiretroviral therapy: A crossâsectional study in a dermatology referral hospital
Abstract Background More than 90% of human immunodeficiency virus (HIV)âinfected patients will develop at least one type of skin disorder during the course of the disease. The prevalence and severity of skin disease commonly seen in HIVâinfected patients has decreased in the era of combination antiretroviral therapy (cART). Few studies in Ethiopia have shown the magnitude of skin problems among adult patients on cART. The aim of this study is to describe the pattern of skin disease among adult patients who are on cART. Methods Crossâsectional observational study at ALERT Hospital from April 2018 to November 2018. Patterns of clinically diagnosed skin diseases were summarized descriptively. Result A total of 572 patients were evaluated. In total, 412 (72%) were female and the mean age of study participants was 40 (SDÂ =Â 10.4). The median CD4 count at the time of diagnosis and start of cART were 178 (R 5â2000) and 168 cells/ÎŒl (R 5â1327), respectively. The mean duration of cART was 8 (SDÂ =Â 3) years. 89.3% of patients were on first line and 7% on second line of cART regimen. Noninfectious inflammatory skin disorders (40.9%) were the most common concomitant diagnosis followed by infectious diseases (34.9%), infestation (7.7%), pigmentary disorders (6.3%) and cutaneous drug eruption (0.7%), respectively. Among the inflammatory skin disorders, 56.5% presented with eczema. One patient had Kaposi sarcoma. Conclusion Noninfectious inflammatory skin disorders are the most common concomitant skin disease in HIVâinfected patients, with eczema being most prevalent. Infectious skin diseases were also common presentations. In our study, AIDSâdefining skin conditions were rare
In situ characterization of pin diode waveforms using electroâoptic sampling
In situ measurements of nonlinear waveforms produced by a PIN diode under largeâsignal excitation have been performed using ultrafast electroâoptic (EO) sampling.The waveforms were sampled using an EO probe positioned immediately after the diode. These data validate a nonlinear model and improve representation of the waveform across the circuit. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2653â2656, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27119Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/93525/1/27119_ftp.pd
A measurement of the evolution of Interatomic Coulombic Decay in the time domain
During the last 15 years a novel decay mechanism of excited atoms has been
discovered and investigated. This so called ''Interatomic Coulombic Decay''
(ICD) involves the chemical environment of the electronically excited atom: the
excitation energy is transferred (in many cases over long distances) to a
neighbor of the initially excited particle usually ionizing that neighbor. It
turned out that ICD is a very common decay route in nature as it occurs across
van-der-Waals and hydrogen bonds. The time evolution of ICD is predicted to be
highly complex, as its efficiency strongly depends on the distance of the atoms
involved and this distance typically changes during the decay. Here we present
the first direct measurement of the temporal evolution of ICD using a novel
experimental approach.Comment: 6 pages, 4 figures, submitted to PR
Parity assignments in 172,174Yb using polarized photons and the K quantum number in rare earth nuclei
The 100 % polarized photon beam at the High Intensity gamma-ray Source (HIgS)
at Duke University has been used to determine the parity of six dipole
excitations between 2.9 and 3.6 MeV in the deformed nuclei 172,174 Yb in photon
scattering (g,g') experiments. The measured parities are compared with previous
assignments based on the K quantum number that had been assigned in Nuclear
Resonance Fluorescence (NRF) experiments by using the Alaga rules. A systematic
survey of the relation between gamma-decay branching ratios and parity quantum
numbers is given for the rare earth nuclei.Comment: 5 pages, 6 figures, to be published in Phys. Rev.
Seeing the smart city on Twitter: Colour and the affective territories of becoming smart
This paper pays attention to the immense and febrile field of digital image files which picture the smart city as they circulate on the social media platform Twitter. The paper considers tweeted images as an affective field in which flow and colour are especially generative. This luminescent field is territorialised into different, emergent forms of becoming âsmartâ. The paper identifies these territorialisations in two ways: firstly, by using the data visualisation software ImagePlot to create a visualisation of 9030 tweeted images related to smart cities; and secondly, by responding to the affective pushes of the image files thus visualised. It identifies two colours and three ways of affectively becoming smart: participating in smart, learning about smart, and anticipating smart, which are enacted with different distributions of mostly orange and blue images. The paper thus argues that debates about the power relations embedded in the smart city should consider the particular affective enactment of being smart that happens via social media. More generally, the paper concludes that geographers must pay more attention to the diverse and productive vitalities of social media platforms in urban life and that this will require experiment with methods that are responsive to specific digital qualities
Web-based physiotherapy for people affected by multiple sclerosis: a single blind, randomized controlled feasibility study
Objective:
To examine the feasibility of a trial to evaluate web-based physiotherapy compared to a standard home exercise programme in people with multiple sclerosis.
Design:
Multi-centre, randomized controlled, feasibility study.
Setting:
Three multiple sclerosis out-patient centres.
Participants:
A total of 90 people with multiple sclerosis (Expanded Disability Status Scale 4â6.5).
Interventions:
Participants were randomized to a six-month individualized, home exercise programme delivered via web-based physiotherapy (nâ=â45; intervention) or a sheet of exercises (nâ=â45; active comparator).
Outcome measures:
Outcome measures (0, three, six and nine months) included adherence, two-minute walk test, 25 foot walk, Berg Balance Scale, physical activity and healthcare resource use. Interviews were undertaken with 24 participants and 3 physiotherapists.
Results:
Almost 25% of people approached agreed to take part. No intervention-related adverse events were recorded. Adherence was 40%â63% and 53%â71% in the intervention and comparator groups. There was no difference in the two-minute walk test between groups at baseline (Intervention-80.4(33.91)m, Comparator-70.6(31.20)m) and no change over time (at six-month Intervention-81.6(32.75)m, Comparator-74.8(36.16)m. There were no significant changes over time in other outcome measures except the EuroQol-5 Dimension at six months which decreased in the active comparator group. For a difference of 8(17.4)m in two-minute walk test between groups, 76 participants/group would be required (80% power, Pâ>â0.05) for a future randomized controlled trial.
Conclusion:
No changes were found in the majority of outcome measures over time. This study was acceptable and feasible by participants and physiotherapists. An adequately powered study needs 160 participants
- âŠ