Association results of the two SNPs with risk of <i>S. japonicum</i> infection in the discovery, replicative and combined studies.

<p>Adjusted for age, gender, smoking and drinking.</p><p><i>P</i><1.163×10⁻³ means significant value by Bonferroni correction based on the total number of markers genotyped.</p

Variables associated with presence or absence of advanced hepatic fibrosis (grade III/IV) in the discovery, replicative and combined cohorts with univariate and multivariate analysis.

<p>(A) Analysis in the discovery cohort. (B) Analysis in the replicative cohort. (C) Analysis in the combined cohort.</p

Association of (A) haplotypes and (B) diplotypes on 9q33.3 with risk of hepatic fibrosis in chronic S. japonicum infected Adults in the discovery study.

<p>Block 1, rs12343206–rs10733669; Block 2, rs11355458–rs17840761–rs17840762–rs391957; Block 3, rs10819146–rs531599; Block 4, rs2454217–rs487914–rs488039. RR, relative risk; CI, confidence interval. Unadjusted RR was calculated using Pearson Chi-square test. Adjusted RR was adjusted for age, gender, smoking, drinking and HBsAg. d, the deleted base.</p

Clinical and laboratory features of the subjects included in the study^*.

<p>*HF, hepatic fibrosis; SD, standard deviation; BMI, body mass index; WBC, white blood cell; HBV, hepatitis B virus; AFP, alpha-fetal protein; T-Bil, total bilirubin; ALB, albumin; ALT, alanine transaminase.</p>†<p>Length of left liver lobe, a longitudinal section at left parasternal line. Length of right liver lobe, anterior axillary view and maximum oblique diameter between front and back sections with inspiration.</p>‡<p>Thickness of spleen from hilum to opposite section. Length of spleen in left oblique view with maximum length in a section through the splenic hilus.</p

Association results of two SNPs with risk of hepatic fibrosis in chronic S. japonicum infected adults in the discovery, replication and combined studies.

<p>Unadjusted RR was calculated using Pearson Chi-square test. Adjusted RR was adjusted for age, gender, smoking, drinking and HBsAg. d, the deleted base.</p

Analysis of the statistical interactions between rs10118570 and rs391957 in the discovery, replicative and combined cohorts.

<p>*<i>P</i>_int, <i>P</i> value for the interaction.</p><p><i>P</i>_int<0.0167 means significant value by Bonferroni correction based on the total number of studies.</p

The ultrasonography diagnosis criteria of hepatic fibrosis in schistosomiasis endemic regions in China.

<p>The ultrasonography diagnosis criteria of hepatic fibrosis in schistosomiasis endemic regions in China.</p