Single Monomer for Multiple Tasks: Polymerization Induced Self-Assembly, Functionalization and Cross-Linking, and Nanoparticle Loading

Efficient preparation of multifunctional nano-objects with controlled morphologies in one step at high concentrations is synthetically challenging, yet is highly desirable, in a broad range of materials applications. Herein, we address this synthetic hurdle by introducing a single commodity monomer 2-(acetoacetoxy)­ethyl methacrylate (AEMA) to realize multiple functions. Facile preparation of both nanospheres and vesicles via polymerization induced self-assembly at concentrations of 20–30% provided defined polymeric nanomaterials with reactive handles inherent to the AEMA units. High-yielding keto-alkoxylamine chemistry was utilized to decorate and cross-link the nano-objects. Nanoparticle loading into the designated location within both nano-objects was exemplified with in situ formation of silver nanoparticles. The concept of using a single monomer capable of both morphology control and multifunctionalization is expected to offer significant opportunities in functional nanomaterials