55 research outputs found
Date of Planting Studies of Winter Wheat and Winter Barley in Relation to Root and Crown Rot Grain Yields and Quality
This study was undertaken to determine the nature of root and crown rot of wheat and to ascertain the proper time to plant winter wheat so as to conserve moisture, minimize root and crown rot and thereby maximize yield. Studies conducted for 15 years at several locations in western Nebraska reveal that planting date is a significant factor for higher yields, particularly in certain years
Results of the Cooperative Uniform Soybean Tests, 1947 Part I. North Central States
United States Department of Agriculture, Agricultural Research Administration; Bureau of Plant Industry, Soils, and Agricultural Engineering, Division of Forage Crops and Diseases Cooperating with State Agricultural Experiment Station
Results of the Cooperative Uniform Soybean Tests, 1946 Part I. North Central States
United States Department of Agriculture, Agricultural Research Administration; Bureau of Plant Industry, Soils, and Agricultural Engineering, Division of Forage Crops and Diseases Cooperating with State Agricultural Experiment Station
Filamin-A Regulates Neutrophil Uropod Retraction through RhoA during Chemotaxis
Filamin-A (FLNa) has been shown to be a key cross-linker of actin filaments in the leading edge of a motile melanoma cell line, however its role in neutrophils undergoing chemotaxis is unknown. Using a murine transgenic model in which FLNa is selectively deleted in granulocytes, we report that, while neutrophils lacking FLNa show normal polarization and pseudopod extension, they exhibit obvious defects in uropod retraction. This uropod retraction defect was found to be a direct result of reduced FLNa mediated activation of the small GTPase RhoA and myosin mediated actin contraction in the FLNa null cells. This results in a neutrophil recruitment defect in FLNa null mice. The compensatory increase in FLNb levels that was observed in the FLNa null neutrophils may be sufficient to compensate for the lack of FLNa at the leading edge allowing for normal polarization, however this compensation is unable to regulate RhoA activated tail retraction at the rear of the cell
Structural and Functional Evaluation of C. elegans Filamins FLN-1 and FLN-2
Filamins are long, flexible, multi-domain proteins composed of an N-terminal actin-binding domain (ABD) followed by multiple immunoglobulin-like repeats (IgFLN). They function to organize and maintain the actin cytoskeleton, to provide scaffolds for signaling components, and to act as mechanical force sensors. In this study, we used transcript sequencing and homology modeling to characterize the gene and protein structures of the C. elegans filamin orthologs fln-1 and fln-2. Our results reveal that C. elegans FLN-1 is well conserved at the sequence level to vertebrate filamins, particularly in the ABD and several key IgFLN repeats. Both FLN-1 and the more divergent FLN-2 colocalize with actin in vivo. FLN-2 is poorly conserved, with at least 23 IgFLN repeats interrupted by large regions that appear to be nematode-specific. Our results indicate that many of the key features of vertebrate filamins are preserved in C. elegans FLN-1 and FLN-2, and suggest the nematode may be a very useful model system for further study of filamin function
EC1811 Seed Treatment and Inoculation of Legumes
Extension Circular 1811. This circular is about seed treatment, and inoculation of legumes
EC76-1833 Lawn Diseases in the Midwest
Extension Circular 76-1833 is about different lawn diseases in the Midwest.
Also published as North Central Regional Extension Publication No. 1
EC69-1833 Lawn Diseases in the Midwest
Extension circular 69-1833 is about lawn diseases in Midwest.
Also published as North Central Regional Extension Publication No. 1
EC73-1833 Lawn Diseases in the Midwest
Extension circular 73-1833 is about lawn diseases in the Midwest
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