Horizontal dynamic response of a tubular pile based on the Timoshenko theory

Horizontally vibrating characteristics of a tubular pile in saturated soil layer are studied in this paper. Governing equations of the pile is deduced based on the popular Timoshenko theory. Analytical solutions of the pile response are derived based on the continuous boundary conditions in the pile-soil interface. Accordingly, analytical expressions of the pile impedances are obtained. Based on it, a comparison with the Euler-Bernoulli Model is performed to verify this solution. Parametric analyses are carried out to study horizontal responses of the tubular pile

Analysis of Mainland China’s International Air Cargo Network: Status Quo and Challenges

Based on air cargo import and export statistics of China Customs, the international air cargo network structure and its flow characteristics in mainland China were studied in this paper. Overall development trends and flow distribution of international air cargo in mainland China were analysed. The major air cargo import and export countries (regions), the main categories of commodities, and the major customs and hub airports were identified. Through our study, a relatively complete view of international air cargo network in mainland China was constructed, in which the major flight routes linking destinations and sources of international air cargo as well as the categories and amounts of air cargo could be revealed. This paper also includes challenges to the further development of mainland China\u27s international air cargo, and proposals to meet these challenges

Anti-Amyloidogenic and Anti-Apoptotic Role of Melatonin in Alzheimer Disease

Alzheimer disease (AD) is an age-related neurodegenerative disorder characterized by the presence of senile plaques, neurofibrillary tangles and neuronal loss. Amyloid-β protein (Aβ) deposition plays a critical role in the development of AD. It is now generally accepted that massive neuronal death due to apoptosis is a common characteristic in the brains of patients suffering from neurodegenerative diseases, and apoptotic cell death has been found in neurons and glial cells in AD. Melatonin is a secretory product of the pineal gland; melatonin is a potent antioxidant and free radical scavenger and may play an important role in aging and AD. Melatonin decreases during aging and patients with AD have a more profound reduction of this indoleamine. Additionally, the antioxidant properties, the anti-amyloidogenic properties and anti-apoptotic properties of melatonin in AD models have been studied. In this article, we review the anti-amyloidogenic and anti-apoptotic role of melatonin in A

Numerical Simulation for Thermal Shock Resistance of Ultra-High Temperature Ceramics Considering the Effects of Initial Stress Field

Taking the hafnium diboride ceramic as an example, the effects of heating rate, cooling rate, thermal shock initial temperature, and external constraint on the thermal shock resistance (TSR) of ultra-high temperature ceramics (UHTCs) were studied through numerical simulation in this paper. The results show that the external constraint has an approximately linear influence on the critical rupture temperature difference of UHTCs. The external constraint prepares a compressive stress field in the structure because of the predefined temperature field, and this compressive stress field relieves the tension stress in the structure when it is cooled down and then it improves the TSR of UHTCs. As the thermal shock initial temperature, a danger heating rate (or cooling rate) exists where the critical temperature difference is the lowest

Σ3 CSL boundary distributions in an austenitic stainless steel subjected to multidirectional forging followed by annealing

The effect of processing and annealing temperatures on the grain boundary characters in the ultrafine-grained structure of a 304-type austenitic stainless steel was studied. An S304H steel was subjected to multidirectional forging (MDF) at 500-800°C to total strains of ~4, followed by annealing at 800-1,000°C for 30 min. The MDF resulted in the formation of ultrafine-grained microstructures with mean grain sizes of 0.28-0.85 μm depending on the processing temperature. The annealing behaviour of the ultrafine-grained steel was characterized by the development of continuous post-dynamic recrystallization including a rapid recovery followed by a gradual grain growth. The post-dynamically recrystallized grain size depended on both the deformation temperature and the annealing temperature. The recrystallization kinetics was reduced with an increase in the temperature of the preceding deformatio

Increasing Pyruvate Concentration Enhances Conidial Thermotolerance in the Entomopathogenic Fungus Metarhizium robertsii

The fungal entomopathogens Metarhizium spp. have been developed as environmentally friendly mycoinsecticides. However, heat stress severely reduces the viability of Metarhizium conidia in the field, which is an important obstacle to the successful use of these mycoinsecticides. Heat treatment induces rapid accumulation of pyruvate, which timely scavenges heat-induced ROS (reactive oxygen species) in hyphal cells of M. robertsii. However, in heat-treated conidia, pyruvate accumulation occurs later than the rapid production of ROSs, which could harm the conidial cells. In the present study, a transgenic M. robertsii strain was constructed with the pyruvate kinases gene overexpressed during conidiation. Two independent transformants of the transgenic strain produced conidia under optimal conditions with elevated pyruvate concentration. This inhibits the rapid heat-induced ROS production and prevents the collapse of mitochondrial membrane potential, thereby increasing conidial tolerance to heat stress. In conclusion, the tolerance of M. robertsii conidia to heat stress was improved by increasing the conidial pyruvate concentration, which could be translated into a more effective pest control

Metarhizium robertsii ammonium permeases (MepC and Mep2) contribute to rhizoplane colonization and modulates the transfer of insect derived nitrogen to plants

The endophytic insect pathogenic fungi (EIPF) Metarhizium promotes plant growth through symbiotic association and the transfer of insect-derived nitrogen. However, little is known about the genes involved in this association and the transfer of nitrogen. In this study, we assessed the involvement of six Metarhizium robertsii genes in endophytic, rhizoplane and rhizospheric colonization with barley roots. Two ammonium permeases (MepC and Mep2) and a urease, were selected since homologous genes in arbuscular mycorrhizal fungi were reported to play a pivotal role in nitrogen mobilization during plant root colonization. Three other genes were selected on the basis on RNA-Seq data that showed high expression levels on bean roots, and these encoded a hydrophobin (Hyd3), a subtilisin-like serine protease (Pr1A) and a hypothetical protein. The root colonization assays revealed that the deletion of urease, hydrophobin, subtilisin-like serine protease and hypothetical protein genes had no impact on endophytic, rhizoplane and rhizospheric colonization at 10 or 20 days. However, the deletion of MepC resulted in significantly increased rhizoplane colonization at 10 days whereas ΔMep2 showed increased rhizoplane colonization at 20 days. In addition, the nitrogen transporter mutants also showed significantly higher 15N incorporation of insect derived nitrogen in barley leaves in the presence of nutrients. Insect pathogenesis assay revealed that disruption of MepC, Mep2, urease did not reduce virulence toward insects. The enhanced rhizoplane colonization of ΔMep2 and ΔMepC and insect derived nitrogen transfer to plant hosts suggests the role of MepC and Mep2 in Metarhizium-plant symbiosis.Brock University Library Open Access Publishing Fun

The distribution and characteristics of suspended particulate matter in the Chukchi Sea

Samples taken from the Chukchi Sea (CS) during the 4th Chinese National Arctic Research Expedition, 2010, were analyzed to determine the content and composition of suspended particulate matter (SPM) to improve our understanding of the distribution, sources and control factors of the SPM there. The results show that the SPM in the water column is highest in the middle and near the bottom in the south and central–north CS, followed by that off the Alaskan coast and in Barrow Canyon. The SPM content is lowest in the central CS. Scanning electron microscope (SEM) analysis shows that the SPM in the south and central–north CS is composed mainly of diatoms, but the dominant species in those two areas are different. The SPM off the Alaskan coast and in Barrow Canyon is composed mainly of terrigenous material with few bio-skeletal clasts. The distribution of temperature and salinity and the correlation between diatom species in SPM indicate that the diatom dominant SPM in the south CS is from the Pacific Ocean via the Bering Strait in summer. The diatom dominant SPM in the central–north CS is also from Pacific water, which reaches the CS in winter. The SPM in the middle and near the bottom of the water column off the Alaskan coast and in Barrow Canyon is from Alaskan coastal water and terrigenous material transported by rivers in Alaska