Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients-0

Stains the cytoplasm of capillary endothelial cells(black arrow) and some glial cells(white arrow). (A) parenchymal section from epileptic patient with arteriovenous malformations (magnification ×200). (B) parenchymal section from control patient with arteriovenous malformations(magnification ×200).<p><b>Copyright information:</b></p><p>Taken from "Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients"</p><p>http://www.biomedcentral.com/1471-2202/9/67</p><p>BMC Neuroscience 2008;9():67-67.</p><p>Published online 18 Jul 2008</p><p>PMCID:PMC2490696.</p><p></p

Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients-1

RP method. Endothelial cells were indicated with black arrow and glial cells/astrocytes were indicated with white arrow. (A, B) GST-π protein expression in temporal subcortex white matter from an epileptic patient with hippocampal sclerosis. Positive GST-π staining was mainly found at the cytoplasm of astrocyte-like cells and capillary endothelial cells (A, magnification ×100; B, magnification ×200). (C,D) GST-π protein expression in temporal subcortex white matter from an epileptic patient with arteriovenous malformations. Immunostaining is in the cytoplasm of astrocyte-like cells and capillary endothelial cells (C, magnification ×100; D, magnification ×200). (E, F) GST-π protein expression in temporal subcortex white matter from a patient of control group. Immunostaining is in capillary endothelial cells and some glial cells (E, magnification ×100; F, magnification ×200). (G) GST-π protein expression in brain from an epileptic patient with hippocampal sclerosis. Immunostaining is not detected in gyrus dentatus of hippocampus. (magnification ×100).<p><b>Copyright information:</b></p><p>Taken from "Expressions of glutathione S-transferase alpha, mu, and pi in brains of medically intractable epileptic patients"</p><p>http://www.biomedcentral.com/1471-2202/9/67</p><p>BMC Neuroscience 2008;9():67-67.</p><p>Published online 18 Jul 2008</p><p>PMCID:PMC2490696.</p><p></p

Nanoscale Structural Evolution and Anomalous Mechanical Response of Nanoglasses by Cryogenic Thermal Cycling

One of the central themes in the amorphous materials research is to understand the nanoscale structural responses to mechanical and thermal agitations, the decoding of which is expected to provide new insights into the complex amorphous structural-property relationship. For common metallic glasses, their inherent atomic structural inhomogeneities can be rejuvenated and amplified by cryogenic thermal cycling, thus can be decoded from their responses to mechanical and thermal agitations. Here, we reported an anomalous mechanical response of a new kind of metallic glass (nanoglass) with nanoscale interface structures to cryogenic thermal cycling. As compared to those metallic glasses by liquid quenching, the Sc₇₅Fe₂₅ (at. %) nanoglass exhibits a decrease in the Young’s modulus but a significant increase in the yield strength after cryogenic cycling treatments. The abnormal mechanical property change can be attributed to the complex atomic rearrangements at the short- and medium- range orders due to the intrinsic nonuniformity of the nanoglass architecture. The present work gives a new route for designing high-performance metallic glassy materials by manipulating their atomic structures and helps for understanding the complex atomic structure–property relationship in amorphous materials