139 research outputs found
Western blot analysis of BDNF and GDNF in human milk.
<p><b>A:</b> BDNF band at approximately 27 kDa. <b>B:</b> GDNF band at approximately 20 kDa.</p
1‑Methyl Boratabenzene Yttrium Alkyl: A Highly Active Catalyst for Dehydrocoupling of Me<sub>2</sub>NH·BH<sub>3</sub>
Catalytic
activity of rare-earth metal complexes for dehydrocoupling
of Me<sub>2</sub>NH·BH<sub>3</sub> is deeply ligand- and metal
ion-dependent, and 1-methyl boratabenzene yttrium alkyl shows very
high activity for the reaction (TOF > 1000 h<sup>–1</sup>).
The transformation of Me<sub>2</sub>NH·BH<sub>3</sub> into [Me<sub>2</sub>N–BH<sub>2</sub>]<sub>2</sub> proceeds through an intermediate
Me<sub>2</sub>NH–BH<sub>2</sub>–NMe<sub>2</sub>–BH<sub>3</sub>
New <sup>1</sup>H NMR-Based Technique To Determine Epoxide Concentrations in Oxidized Oil
A new method to determine epoxide
concentrations in oxidized oils
was developed and validated using <sup>1</sup>H NMR. Epoxides derived
from lipid oxidation gave signals between 2.90 and 3.24 ppm, well
separated from the signals of other lipid oxidation products. To calibrate,
soybean oils with a range of epoxide concentrations were synthesized
and analyzed using <sup>1</sup>H NMR by taking the <i>sn</i>-1,3 glycerol protons (4.18, 4.33 ppm) as internal references. The <sup>1</sup>H NMR signals were compared to the epoxide content determined
by titration with hydrogen bromide (HBr)–acetic acid solution.
As expected, the signal response increased with concentration linearly
(<i>R</i><sup>2</sup> = 99.96%), and validation of the method
gave results comparable to those of the HBr method. A study of the
oxidative stability of soybean oil was performed by applying this
method to monitor epoxides during thermal lipid oxidation. The epoxide
content increased over time and showed a different trend compared
to peroxide value (PV). A phenomenological model was suggested to
model epoxides derived from lipid oxidation
Cytokines in the human milk from Chinese women during day 3, 10, and 30 after parturition (n = 42).
<p>*number of donors equal to 40.</p
Cytokines in human milk from Chinese women during day 3, 10, 30, and 90 after parturition (n = 24).
<p>Cytokines in human milk from Chinese women during day 3, 10, 30, and 90 after parturition (n = 24).</p
Interaction of Cobalt Nanoparticles with Oxygen- and Nitrogen-Functionalized Carbon Nanotubes and Impact on Nitrobenzene Hydrogenation Catalysis
The type and the amount of functional
groups on the surface of
carbon nanotubes (CNTs) were tuned to improve the activity of supported
Co nanoparticles in hydrogenation catalysis. Surface nitrogen species
on CNTs significantly promoted the decomposition of the cobalt precursor
and the reduction of cobalt oxide, and improved the resistance of
metallic Co against oxidation in ambient atmosphere. In the selective
hydrogenation of nitrobenzene in the gas phase, Co supported on CNTs
with the highest surface nitrogen content showed the highest activity,
which is ascribed to the higher reducibility and the lower oxidation
state of the Co nanoparticles under reaction conditions. For Co nanoparticles
supported on CNTs with a smaller amount of surface nitrogen groups,
a repeated reduction at 350 °C was essential to achieve a comparable
high catalytic activity reaching 90% conversion at 250 °C, pointing
to the importance of nitrogen species for the supported Co nanoparticles
in nitrobenzene hydrogenation
Positive association between levels of S100B and BDNF in human milk.
<p>The solid line represents the predicted regression line determined from repeated-measures analysis of S100B and BDNF concentrations 3 month after parturition. n = 24, P = 0.037<0.05.</p
S100B levels in human milk were closely correlated with BMI.
<p>The solid line represents the predicted regression line determined from measures analysis of human milk collected 3 days after birth. Pearson correlation coefficient (<i>r</i>) was 0.335. <i>P</i><0.05. n = 42.</p
Bismuth-Induced Inactivation of Ferric Uptake Regulator from <i>Helicobacter pylori</i>
Ferric uptake regulator
(Fur) of <i>Helicobacter pylori</i> is a global regulator
that is important for bacterial colonization and survival within the
gastric mucosa. <i>H. pylori</i> Fur (<i>Hp</i>Fur) is unique in its ability to regulate gene expression in both
metal-bound (holo-Fur) and metal-free (apo-Fur) forms. Bismuth-based
drugs are widely used for the treatment of <i>H. pylori</i> infection. However, the mechanism of action of bismuth drug was
not fully understood. Recently, it has been reported that bismuth
drugs could interfere with the bacterial ferric uptake pathway and
inhibit bacterial growth, implying intrinsic correlation between bismuth
drug and bacterial iron metabolism. Herein, we demonstrate that BiÂ(III)
binds to <i>Hp</i>Fur protein specifically at the physiologically
important S1 site, which further leads to protein oligomerization
and loss of DNA binding capability. The targeting of <i>Hp</i>Fur by bismuth drugs significantly reduced transcription levels of
its regulated genes, which are crucial for bacterial physiology and
metabolism. Our studies present direct evidence that perturbation
of iron metabolism in <i>H. pylori</i> by bismuth might
serve as one of the mechanisms for the antimicrobial activity of bismuth
drugs
Reusable Hydrophilic–Superhydrophobic Patterned Weft Backed Woven Fabric for High-Efficiency Water-Harvesting Application
Here we report a hydrophilic–superhydrophobic
patterned
surface, which was fabricated via a readily weaving method to mimic
the hybrid wettable areas arrangements on the back of Stenocara beetles. The fabric exhibited excellent
water-harvesting rate (WHR) of 1267.2 mg h<sup>–1</sup> cm<sup>–2</sup>. Besides, the fabric could be recycled for 10 times
while the WHR stayed almost invariant. This work offers a very feasible
and novel tool to achieve mass production of water-harvesting materials,
providing novel ideas to bridge traditional textile industry with
environmental conservation in the future
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