6,212 research outputs found
Australian Real Estate Stock Reactions to FIRB Regulation Changes
This study analyzes the share price reactions to real estate development and building/construction materials corporations in relation to FIRB rule changes. It appears companies as a whole were indifferent to the rule changes; however individual securities returns were wildly different. These findings suggest that the FIRB rule changes had a mixed effect on different corporations possibly based on their exposure to the Australian real estate market
Sharp-edged geometric obstacles in microfluidics promote deformability-based sorting of cells
Sorting cells based on their intrinsic properties is a highly desirable
objective, since changes in cell deformability are often associated with
various stress conditions and diseases. Deterministic lateral displacement
(DLD) devices offer high precision for rigid spherical particles, while their
success in sorting deformable particles remains limited due to the complexity
of cell traversal in DLDs. We employ mesoscopic hydrodynamics simulations and
demonstrate prominent advantages of sharp-edged DLD obstacles for probing
deformability properties of red blood cells (RBCs). By consecutive sharpening
of the pillar shape from circular to diamond to triangular geometry, a
pronounced cell bending around an edge is achieved, serving as a deformability
sensor. Bending around the edge is the primary mechanism, which governs the
traversal of RBCs through such DLD device. This strategy requires an
appropriate degree of cell bending by fluid stresses, which can be controlled
by the flow rate, and exhibits good sensitivity to moderate changes in cell
deformability. We expect that similar mechanisms should be applicable for the
development of novel DLD devices that target intrinsic properties of many other
cells.Comment: 16 pages, 9 figure
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