1,886 research outputs found

    A Case of Prune Belly Syndrome

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    Prune belly syndrome (PBS) is a rare congenital disorder characterized by deficient abdominal wall muscles, urinary tract malformation, and, in males, cryptorchidism. We present a case of PBS in China. The patient was a newborn baby boy who had wrinkled, “prune-like” abdominal skin, bilateral cryptorchidism, and urinary system malformation, complicated with hypoplasia of the lung and branch of the coronary artery–right ventricular fistula. His kidney function was inadequate. The patient subsequently died at age 28 days due to septicemia from a severe urinary tract infection

    N,N′-Bis(2-quinolylcarbon­yl)hydrazine

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    The title compound, C20H14N4O2, crystallizes in the ortho­rhom­bic system with a crystallographic twofold axis through the N—N bond. The mol­ecule is non-planar and the dihedral angle between two amide groups is 74.9 (2)°. An intra­molecular N—H⋯N hydrogen bond is present. In the crystal, the mol­ecules are packed in chains running along the c axis through inter­molecular N—H⋯O hydrogen bonds. These chains are further stabilized by inter­molecular C—H⋯O hydrogen bonds and C—H⋯π inter­actions leading to the formation of a three-dimensional network

    Reverse Projection: Real-Time Local Space Texture Mapping

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    We present Reverse Projection, a novel projective texture mapping technique for painting a decal directly to the texture of a 3D object. Designed to be used in games, this technique works in real-time. By using projection techniques that are computed in local space textures and outward-looking, users using low-end android devices to high-end gaming desktops are able to enjoy the personalization of their assets. We believe our proposed pipeline is a step in improving the speed and versatility of model painting.Comment: SIGGRAPH 202

    4-Amino-3-(4-pyrid­yl)-1,2,4-triazole-5(4H)-thione

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    In the title mol­ecule, C7H7N5S, the pyridyl and triazole rings form a dihedral angle of 20.07 (6)°. Inter­molecular N—H⋯N hydrogen bonds link the mol­ecules into chains extended in the direction [10]. Further stability is provided by π⋯π stacking inter­actions, indicated by short distances between the centroids of triazole rings [3.480 (5) Å] and pyridyl rings [3.574 (5) Å] of neighbouring mol­ecules

    Tris(dibenzoyl­methanido-κ2 O,O′)[(6R,8R)-(−)-7,7-dimethyl-3-(2-pyrid­yl)-5,6,7,8-tetra­hydro-6,8-methano­isoquinoline-κ2 N,N′]terbium(III)

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    In the title compound, [Tb(C15H11O2)3(C17H18N2)], the 7,7-dimethyl-3-(2-pyrid­yl)-5,6,7,8-tetra­hydro-6,8-methano­iso­quin­oline (LRR) ligand coordinates to TbIII through the two N atoms of the heterocycle. The metal centre is also chelated by three deprotonated 1,3-diphenyl­propane-1,3-dione (dbm) ligands, forming enanti­omerically pure [Tb(dbm)3 LRR]. The TbIII atom is located in a distorted square anti­prism of eight coordinating atoms (six O and two N atoms)

    LAPTM4B Targeting as Potential Therapy for Hepatocellular Carcinoma

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    HCC is one of the most common cancers worldwide with high prevalence, recurrence, and lethality. The curative rate is not satisfactory. LAPTM4B is a novel driver gene of HCC first indentified by our group. It is over-expressed in 87.3% of HCC. The expression levels of the encoded LAPTM4B-35 protein in HCC is also over-expressed in 86.2% of HCC and shows a significant positive correlation with pathological grade, metastasis, and recurrence, and a negative correlation with postoperative overall- and cancer free- survival of HCC patients. Moreover, HCC cells showing high expression of LAPTM4B-35 show a strong tendency to metastasize and enhanced drug resistance. Overexpression of this gene promotes tumorigenesis, faster growth of human HCC xenografts and metastasis in nude mice, and leads to anti-apoptosis, deregulation of proliferation, enhancement of migration and invasion, as well as multi-drug resistance. In addition, overexpression of LAPTM4B-35 leads to accumulation of a number of oncoproteins and to down-regulation of a number of tumor suppressing proteins. By contrary, knockdown of endogenous LAPTM4B-35 via RNAi results in remarkable inhibition of xenograft growth and metastasis of human HCC in nude mice. Also, RNAi knockdown of LAPTN4B-35 can reverse the cellular and molecular malignant phenotypes noted above

    Consumer perception towards internet health information resources

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    This research aims to examine consumer perception towards Internet health information resources. Data was collected among 205 respondents by using convenience sampling and was analyzed using descriptive statistics. Descriptively, there was more females' respondent than males' respondent in this survey where all of them are recently undertaking degree courses. The result shows perceived ease of use and perceived usefulness was the main factor that motivates students in using internet health information resources

    Interrelated Thermalization and Quantum Criticality in a Lattice Gauge Simulator

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    Gauge theory and thermalization are both foundations of physics and nowadays are both topics of essential importance for modern quantum science and technology. Simulating lattice gauge theories (LGTs) realized recently with ultracold atoms provides a unique opportunity for carrying out a correlated study of gauge theory and thermalization in the same setting. Theoretical studies have shown that an Ising quantum phase transition exists in this implemented LGT, and quantum thermalization can also signal this phase transition. Nevertheless, it remains an experimental challenge to accurately determine the critical point and controllably explore the thermalization dynamics in the quantum critical regime due to the lack of techniques for locally manipulating and detecting matter and gauge fields. Here, we report an experimental investigation of the quantum criticality in the LGT from both equilibrium and non-equilibrium thermalization perspectives by equipping the single-site addressing and atom-number-resolved detection into our LGT simulator. We accurately determine the quantum critical point agreed with the predicted value. We prepare a Z2|Z_{2}\rangle state deterministically and study its thermalization dynamics across the critical point, leading to the observation that this Z2|Z_{2}\rangle state thermalizes only in the critical regime. This result manifests the interplay between quantum many-body scars, quantum criticality, and symmetry breaking.Comment: 6+4 pages, 4+7 figure
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