Nothing Could Be Finer

You will not want to m1ss the 49th annual conference of the Association of Christian Librarians, June 13-15, 2005 in Columbia, South Carolina. The planning team has pulled together a strong program of expert speakers and workshops led by your ACL colleagues. Excellent pre-confe rences will provide more in-depth educational opportunities. T he schedule is organized to increase time for fellowship and spiritual enrichment and the Christian networking that makes ACL conferences unique. Our hosts, the staff of the G. Allen Fleece Library at Columbia International University, are preparing to provide for your every need

Asking God about the date you will die: HIV testing as a zone of uncertainty in rural Malawi

Testing for HIV is becoming more available in Africa. Global advocates of testing see it as key to AIDS prevention. However, testing is not always perceived as a good thing by people at risk. Here, we consider testing from the perspective of people in a high-prevalence community. Using qualitative data from rural Malawi, we show that the decision to test is not as straightforward as suggested in the testing advocacy literature, but is marked by uncertainty and ambivalence. Reluctance to test is connected to the perception that testing inevitably leads to a positive diagnosis, and subsequent deterioration and death. This fear is in turn linked to overestimation of the transmissibility of HIV. We recommend that testing advocates address this concern that being tested means having a death sentence pronounced, and emphasize the benefits of testing for the majority who are HIV-negative, as well as the minority who are HIV-positive.ambivalence, HIV testing, Malawi

Heterozygous deletion of both sclerostin (Sost) and connexin43 (Gja1) genes in mice is not sufficient to impair cortical bone modeling

Connexin43 (Cx43) is the main gap junction protein expressed in bone forming cells, where it modulates peak bone mass acquisition and cortical modeling. Genetic ablation of the Cx43 gene (Gja1) results in cortical expansion with accentuated periosteal bone formation associated with decreased expression of the Wnt inhibitor sclerostin. To determine whether sclerostin (Sost) down-regulation might contribute to periosteal expansion in Gja1 deficient bones, we took a gene interaction approach and crossed mice harboring germline null alleles for Gja1 or Sost to generate single Gja1+/-and Sost+/-and double Gja1+/-;Sost+/-heterozygous mice. In vivo μCT analysis of cortical bone at age 1 and 3 months confirmed increased thickness in Sost-/-mice, but revealed no cortical abnormalities in single Gja1+/-or Sost+/-mice. Double heterozygous Gja1+/-Sost+/-also showed no differences in mineral density, cortical thickness, width or geometry relative to wild type control mice. Likewise, 3-point bending measurement of bone strength revealed no significant differences between double Gja1+/-;Sost+/-or single heterozygous and wild type mice. Although these data do not exclude a contribution of reduced sclerostin in the cortical expansion seen in Gja1 deficient bones, they are not consistent with a strong genetic interaction between Sost and Gja1 dictating cortical modeling

Social Networks, HIV/AIDS and Risk Perceptions

Understanding the determinants of individuals’ perceptions of their risk of becoming infected with HIV and their perceptions of acceptable strategies of prevention is an essential step towards curtailing the spread of this disease. We focus in this paper on learning and decision-making about AIDS in the context of high uncertainty about the disease and appropriate behavioral responses, and we argue that social interaction is an important determinant of risk perceptions and the acceptability of behavioral change. Using longitudinal survey data from rural Kenya and Malawi, we test this hypothesis. We investigate whether social interactions—and especially the extent to which social network partners perceive themselves to be at risk –exert causal influences on respondents’ risk perceptions and on one approach to prevention, spousal communication about the threat of AIDS to the couple and their children. The study explicitly allows for the possibility that important characteristics, such as unobserved preferences or community characteristics, determine not only the outcomes of interest but also the size and composition of networks. The most important empirical result is that social networks have significant and substantial effects on risk perception and the adoption of new behaviors even after controlling for unobserved factors.health, AIDS, information, social networks, Africa

How can we measure the causal effects of social networks using observational data? Evidence from the diffusion of family planning and AIDS worries in South Nyanza District, Kenya

This study presents estimates that social networks exert causal and substantial influences on individuals’ attitudes and behaviors. The study explicitly allows for the possibility that social networks are not chosen randomly, but rather that important characteristics such as unobserved preferences and unobserved community characteristics determine not only the outcomes of interest but also the informal conversational networks in which they are discussed. Longitudinal survey data from rural Kenya on family-planning and AIDS are used to estimate the impact of social networks while controlling for their unobserved determinants. There are four major findings: First, the endogeneity of social networks can substantially distort the usual cross-sectional estimates of network influences. Second, social networks have significant and substantial effects even after controlling for unobserved factors that may determine the nature of the social networks. Third, these network effects generally are nonlinear and asymmetric. In particular, they are relatively large for individuals who have at least one network partner who is perceived to be using contraceptives or or to be at high risk of HIV/AIDS, which is consistent with S-shaped diffusion models that have been emphasized in the literature. Fourth, the effects of networks are not confined to the use of family planning by women, the focus of much of the literature on networks in demography, but appear to be more general, influencing responses to HIV/AIDS, and influencing men as well as women. (AUTHORS)

Narratives of Death in Rural Malawi in the Time of AIDS

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116815/1/Ashforth and Watkins Narratives of Death.pd