557 research outputs found

    Honeymoon and Greybeard Loon

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    Group Behavior: Social Context Modulates Behavioral Responses to Sensory Stimuli

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    SummaryA new study reveals an unanticipated role for social context in driving group behavior of a solitary species to a sensory stimulus and is mediated by mechanosensory neurons signaling touch interactions among individuals

    Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa: protocol for a systematic review

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    BACKGROUND: Reports from Africa have suggested that pneumocystis pneumonia (PCP) is a less important cause of morbidity than in the developed world. However, more recent studies have shown high seroprevalence rates of P. jirovecii in healthy individuals with HIV as well as high rates of clinical disease in African children. This suggests that PCP may be more common in Africa than was previously recognised. Understanding the contribution of PCP to disease in HIV-infected individuals in sub-Saharan Africa (SSA) has important implications for diagnosis, management and resource allocation. We therefore propose to conduct a systematic review and meta-analysis in order to investigate the burden of PCP in this population.METHODS AND DESIGN:We plan to search electronic databases and reference lists of relevant articles published from 1995 to May 2013 using broad terms for pneumocystis, HIV/AIDS and sub-Saharan Africa. Studies will be included if they provide clear diagnostic criteria for PCP and well-defined study populations or mortality data (denominator). A novel quality score assessment tool has been developed to ensure fidelity to inclusion criteria, minimise risk of selection bias between reviewers and to assess quality of outcome ascertainment. This will be applied to eligible full-text articles. We will extract data using a standardised form and perform descriptive and quantitative analysis to assess PCP prevalence, mortality and case fatality, as well as the quality of included studies. This review protocol has been published in the PROSPERO International Prospective Register of systematic reviews, registration number CRD42013005530.DISCUSSION:Our planned review will contribute to the diagnosis and management of community-acquired pneumonia in HIV-infected individuals in SSA by systematically assessing the burden of PCP in this population. We also describe a novel quality assessment tool that may be applied to other prevalence reviews

    All Politics Are Local: Nineteenth-Century Mexico Revisited

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    This essay reviews the following works: Popular Politics and Rebellion in Mexico: Manuel Lozada and La Reforma, 1855–1876. By Zachary Brittsan. Nashville: Vanderbilt University Press, 2015. Pp. ix + 220. 55.00cloth.ISBN:9780826520449.Eljefepolıˊtico:UndominionegociadoenelmundoruraldelEstadodeMeˊxico,1856–1911.ByRomanaFalcoˊn.MexicoCity:ElColegiodeMeˊxico;ElColegiodeMichoacaˊn;CIESAS,2015.Pp.9+744.55.00 cloth. ISBN: 9780826520449. El jefe político: Un dominio negociado en el mundo rural del Estado de México, 1856–1911. By Romana Falcón. Mexico City: El Colegio de México; El Colegio de Michoacán; CIESAS, 2015. Pp. 9 + 744. 39.99 paper. ISBN: 9786074627381. Independent Mexico: The Pronunciamiento in the Age of Santa Anna, 1821–1858. By Will Fowler. Lincoln: University of Nebraska Press, 2016. Pp. viii + 362. 40.00paper.ISBN:9780803225398.Mexico’sSupremeCourt:BetweenLiberalIndividualandRevolutionarySocialRights,1867–1934.ByTimothyM.James.Albuquerque:UniversityofMexicoPress,2013.Pp.ix+149.40.00 paper. ISBN: 9780803225398. Mexico’s Supreme Court: Between Liberal Individual and Revolutionary Social Rights, 1867–1934. By Timothy M. James. Albuquerque: University of Mexico Press, 2013. Pp. ix + 149. 45.00 cloth. ISBN: 9780826353788. Conflict and Carnage in Yucatán: Liberals, the Second Empire, and Maya Revolutionaries, 1855–1876. By Douglas W. Richmond. Alabama: University of Alabama Press, 2015. Pp. ix + 177. 49.95cloth.ISBN:9780817318703.LaseˊlitesempresarialesylaindependenciaeconoˊmicadeMeˊxico:EstevandeAntun anoolasvicisitudesdelfundadordelaindustriatextilmoderna,1792–1847.ByEvelyneSanchez.Mexico:PlazayValdeˊsEditores,2013.Pp.ix+363.49.95 cloth. ISBN: 9780817318703. Las élites empresariales y la independencia económica de México: Estevan de Antun~ano o las vicisitudes del fundador de la industria textil moderna, 1792–1847. By Evelyne Sanchez. Mexico: Plaza y Valdés Editores, 2013. Pp. ix + 363. 29.95 paper. ISBN: 9786074026177
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