New Curriculum for the College of Veterinary Medicine

The newly revised curriculum for the first college of veterinary medicine will first appear in the 1967-69 General Catalog. The new program represents a radical departure from the old curriculum. Achieving the changes that have been developed has not come easily. Long hours of discussion, evaluation and debate have been devoted to the problem

Summer Clinics

Many of the veterinary colleges around the country have introduced recent changes in their curricula, designed to improve the quality of their training or to increase the number of students they are able to accept and graduate. One college, Texas A & M, has gone to a trimester system to provide year around training and shorten the period required for graduation. Another, Michigan State, accepts two classes per year and plans to increase the number of students it graduates in this fashion. Several others have gone to a program of summer clinics for a portion of the vacation period between the junior and senior year in order to provide more organized training in the clinical disciplines

Bovine and Porcine Somatotropin

Among the more recent biological tools being proposed and studied for dairy and swine management programs is somatotropin (growth hormone or GH). Advocates claim that somatotropin improves efficiency and thus decreases the cost of production in dairy cows and growing swine. With Food and Drug Administration (F&DA) approval of bovine somatotropin (SST) expected within the year in the United States and approval of porcine somatotropin (PST) being sought, food animal veterinarians need to be knowledgeable of somatotropin and must be prepared to advise clients on the use of the product as a management tool

LISA and LISA PathFinder, the endeavour to detect low frequency GWs

This is a review about LISA and its technology demonstrator, LISA PathFinder. We first describe the conceptual problems which need to be overcome in order to set up a working interferometric detector of low frequency Gravitational Waves (GW), then summarise the solutions to them as currently conceived by the LISA mission team. This will show that some of these solutions require new technological abilities which are still under development, and which need proper test before being fully implemented. LISA PathFinder (LPF) is the the testbed for such technologies. The final part of the paper will address the ideas and concepts behind the PathFinder as well as their impact on LISA.Comment: 25 pages, 21 figures, presented at the Spanish Relativity Meeting, Mallorca September 2006. Will be published in Journal of Physics: Conference Series, IOP. To be published in Journal of Physics: Conference Series, IO

Guidelines for the management of glucocorticoids during the peri-operative period for patients with adrenal insufficiency: Guidelines from the Association of Anaesthetists, the Royal College of Physicians and the Society for Endocrinology UK

These guidelines aim to ensure that patients with adrenal insufficiency are identified and adequately supplemented with glucocorticoids during the peri-operative period. There are two major categories of adrenal insufficiency. Primary adrenal insufficiency is due to diseases of the adrenal gland (failure of the hormone-producing gland), and secondary adrenal insufficiency is due to deficient adrenocorticotropin hormone secretion by the pituitary gland, or deficient corticotropin-releasing hormone secretion by the hypothalamus (failure of the regulatory centres). Patients taking physiological replacement doses of corticosteroids for either primary or secondary adrenal insufficiency are at significant risk of adrenal crisis and must be given stress doses of hydrocortisone during the peri-operative period. Many more patients other than those with adrenal and hypothalamic-pituitary causes of adrenal failure are receiving glucocorticoids as treatment for other medical conditions. Daily doses of prednisolone of 5 mg or greater in adults and 10-15 mg.m-2 hydrocortisone equivalent or greater in children may result in hypothalamo-pituitary-adrenal axis suppression if administered for 1 month or more by oral, inhaled, intranasal, intra-articular or topical routes; this chronic administration of glucocorticoids is the most common cause of secondary adrenal suppression, sometimes referred to as tertiary adrenal insufficiency. A pragmatic approach to adrenal replacement during major stress is required; considering the evidence available, blanket recommendations would not be appropriate, and it is essential for the clinician to remember that adrenal replacement dosing following surgical stress or illness is in addition to usual steroid treatment. Patients with previously undiagnosed adrenal insufficiency sometimes present for the first time following the stress of surgery. Anaesthetists must be familiar with the symptoms and signs of acute adrenal insufficiency so that inadequate supplementation or undiagnosed adrenal insufficiency can be detected and treated promptly. Delays may prove fatal

A consensus on the diagnosis and treatment of acromegaly complications

In March 2011, the Acromegaly Consensus Group met to revise and update the guidelines on the diagnosis and treatment of acromegaly complications. The meeting was sponsored by the Pituitary Society and the European Neuroendocrinology Association and included experts skilled in the management of acromegaly. Complications considered included cardiovascular, endocrine and metabolic, sleep apnea, bone diseases, and mortality. Outcomes in selected, related clinical conditions were also considered, and included pregnancy, familial acromegaly and invasive macroadenomas. The need for a new disease staging model was considered, and design of such a tool was proposed

Effective decrease of photoelectric emission threshold from gold plated surfaces

Many applications require charge neutralisation of isolated test bodies and this has been successfully done using photoelectric emission from surfaces which are electrically benign(gold) or superconducting (niobium). Gold surfaces nominally have a high work function ($\sim 5.1$\,eV)which should require deep UV photons for photoemission. In practice it has been found that it can be achieved with somewhat lower energy photons with indicative work functions of ($4.1-4.3$\,eV). A detailed working understanding of the process is lacking and this work reports on a study of the photoelectric emission properties of 4.6x4.6 cm^2 gold plated surfaces, representative of those used in typical satellite applications with a film thickness of 800 nm, and measured surface roughnesses between 7 and 340 nm. Various UV sources with photon energies from 4.8 to 6.2 eV and power outputs from 1 nW to 1000 nW, illuminated a ~0.3 cm^2 of the central surface region at angles of incidence from 0 to 60 degrees. Final extrinsic quantum yields in the range 10 ppm to 44 ppm were reliably obtained during 8 campaigns, covering a ~3 year period, but with intermediate long-term variations lasting several weeks and, in some cases, bake-out procedures at up to 200 C. Experimental results were obtained in a vacuum system with a baseline pressure of ~10^{-7} mbar at room temperature. A working model, designed to allow accurate simulation of any experimental configuration, is proposed.Comment: 35 pages, 12 figure

Using item response theory to explore the psychometric properties of extended matching questions examination in undergraduate medical education

BACKGROUND: As assessment has been shown to direct learning, it is critical that the examinations developed to test clinical competence in medical undergraduates are valid and reliable. The use of extended matching questions (EMQ) has been advocated to overcome some of the criticisms of using multiple-choice questions to test factual and applied knowledge. METHODS: We analysed the results from the Extended Matching Questions Examination taken by 4th year undergraduate medical students in the academic year 2001 to 2002. Rasch analysis was used to examine whether the set of questions used in the examination mapped on to a unidimensional scale, the degree of difficulty of questions within and between the various medical and surgical specialties and the pattern of responses within individual questions to assess the impact of the distractor options. RESULTS: Analysis of a subset of items and of the full examination demonstrated internal construct validity and the absence of bias on the majority of questions. Three main patterns of response selection were identified. CONCLUSION: Modern psychometric methods based upon the work of Rasch provide a useful approach to the calibration and analysis of EMQ undergraduate medical assessments. The approach allows for a formal test of the unidimensionality of the questions and thus the validity of the summed score. Given the metric calibration which follows fit to the model, it also allows for the establishment of items banks to facilitate continuity and equity in exam standards

Infant effortful control mediates relations between nondirective parenting and internalising-related child behaviours in an autism-enriched infant cohort

Internalising problems are common within Autism Spectrum Disorder (ASD); early intervention to support those with emerging signs may be warranted. One promising signal lies in how individual differences in temperament are shaped by parenting. Our longitudinal study of infants with and without an older sibling with ASD investigated how parenting associates with infant behavioural inhibition (8–14 months) and later effortful control (24 months) in relation to 3-year internalising symptoms. Mediation analyses suggest nondirective parenting (8 months) was related to fewer internalising problems through an increase in effortful control. Parenting did not moderate the stable predictive relation of behavioural inhibition on later internalising. We discuss the potential for parenting to strengthen protective factors against internalising in infants from an ASD-enriched cohort