Magnetic resonance cholangiopancreatography in diagnosis of biliary disorders in children - Sharing our experience.

Abstract OBJECTIVE: To evaluate the role of Magnetic Resonance Cholangio-pancreatography in the diagnosis of biliary disorders in children. METHODS: The retrospective study was conducted at Aga Khan University Hospital, Karachi, and comprised data related to the period between August 2005 and December 2013. All children from age of 1 day to 17 years who had undergone Magnetic Rasonance Cholangio-pancreatography examination for suspected pancreaticobiliary disorders were included. Clinical presentation, Magnetic Rasonance Cholangio-pancreatography findings, operative findings and histopathological results were recorded. Sensitivity and specificity of Magnetic Rasonance Cholangio-pancreatography for different diseases was worked out. RESULTS: Of the 50 patients in the study, 12(24%) showed findings of choledochal cyst. Of these patients, 11(91.6%) underwent surgery and operative findings were consistent with choledochal cyst. Only 1(8.3%) who was assessed as biliary atresia was found to have choledochal cyst on surgery Magnetic Resonance Cholangio-pancreatography was found to be 91% sensitive and 100% specific for diagnosis of choledochal cyst with diagnostic accuracy of 98%. CONCLUSIONS: Magnetic Resonance Cholangio-pancreatography is a very accurate non-invasive investigation for the diagnosis of biliary disorders

Transgenic Bt Cotton: Effects on Target and Non-Target Insect Diversity

Occurrence of diversity in ecosystem sustains particular characteristic of a biological community and also ensures stability of the community. Transgenic crops may affect insect biodiversity by unintended impacts on non-target arthropod population. For example, transgenic GM cotton specific to target lepidopterous pests can change the cotton pest spectrum and may induce the growth of new harmful pest species having no pest status. The change in species composition may influence IPM approach in cotton crop. The results of authors’ research studies as well as global impact indicate that GM cotton is highly specific to target pests and has no unintended impact on non-target insect population. GM cotton provides significant season-long field control of target pests (Helicoverpa armigera, Earias spp. and Pectinophora gossypiella), with no significant control of Spodoptera species. The decreased insecticide use in GM cotton has a positive impact on beneficial insect populations and can increase the stability of rare species. Bt cotton has no resistance against non-target sucking insect pests. As GM cotton has no adverse effects on the non-target insect population and can reduce the use of broad-spectrum insecticides, it can become an important tool of IPM program in cotton agro-ecosystem of Pakistan

High Involvement Management Practices and Employees’ OCBs in Banking Sector of Pakistan

This study was designed to evaluate the impact of high involvement HRM practices (HIHRP) on employees’ organizational citizenship behaviors (OCBs) in the context of banking sector of Pakistan. OCBs is considered as an important construct to evaluate the contextual performance of employees. In case of banking sector professionals, it is a highly desired behavior and top management has a greater interest in evaluating contextual performance in addition to the task performance of employees. This study differentiates itself from previous studies by focusing on HIHRP rather than traditional HRM practices. The data was collected from 396 officers working in top six private sector commercial banks of Pakistan. A structured questionnaire was used to collect the data and all responses were recorded on Likert scale. The data was analyzed through correlation and regression analysis and demographic characteristics of the employees were also presented through descriptive statistical techniques. The results show that different types of HIHRP positively influences employees’ OCBs. This study has both theoretical and managerial contributions by empirically examining the relationship between high involvement HRM practices and OCBs in the context of banking sector of Pakistan. The results of this study will help the researchers to better understand the relationship between HRM practices employees’ positive behavioral outcomes like OCBs. In addition, it will also guide the decision makers in adjusting HRM practices to achieve desired behaviors

Band Ligation VersusGlue Injection for Bleeding Gastric Varices

Background : To compare endoscopic variceal sclerotherapy with N-butyl-2-cyanoacrylate- Histoacryl (EVS) and endoscopic variceal band ligation (EBL) for treatment of bleeding gastric varices (GV).Methods: In this  randomized control trial 140 patients  with bleeding gastric varices were included.Bleeding GV patients diagnosed endoscoically were treated with EVS or EBL in two equal groups after randomization. Bleeding control or otherwise was confirmed during the procedure. Patients were followed for 1 month for re-bleeding. Comparison of the patients undergoing EVS or EBL was done in terms of bleeding control and re-bleeding during follow up period. Chi2 test was used to seek statistically significant association in this regard. Results: Endoscopic bleeding control was confirmed in all except 1 of EBL patients who expired. 4 (5.7%) of EVS 10 (14.28%) EBL patients had re-bleeding (P >0.05).Conclusion: EVS and EBL are comparative procedures for treatment ofbleeding GV for control of active bleeding and re-bleeding over one month follow up