62 research outputs found

    Relative Attraction of the Mediterranean Fruit Fly (Diptera: Tephritidae) to the Eight Isomers of Trimedlure

    Get PDF
    ABSTRACT Relative attractiveness tests with the eight individual racemic isomers of trimedlure, teTt-butyl 4(and 5)-chloro-c1s-and tTans-2-methylcyclohexane-l-carboxylate (TML), showed that one of the four cis isomers, TML-Y (teTt-butyl c1s-5-chloro-cis-2-methylcyclohexane-I-carboxylate), was attractive to CeTatitis capitata (Wiedemann) and long lasting. The isomer is present in cis-TML in a concentration of about 5%. The three other cis isomers, which are present in about equal amounts, were unattractive. The relative attractiveness of the four tTans isomers was the same as reported previously. Possible structure-activity relationships are discussed. KEY WORDS Insecta, CeTatitis capitata, attractant, lure MALE MEDITERRANEAN FRUIT FLIES, CeTatitis capitata (Wiedemann) are strongly attracted to trimedlure, tert-butyl 4(and 5)-chloro-cis-and trans-2-methy Icyclohexane-l-carboxylate (TML), which consists of a blend of eight racemic isomers (Beroza et a!. 1961). Commercially synthesized TML contains 90-95% of the four possible trans isomers, which are designated TML-A

    Notch Signaling Regulates Bile Duct Morphogenesis in Mice

    Get PDF
    BACKGROUND: Alagille syndrome is a developmental disorder caused predominantly by mutations in the Jagged1 (JAG1) gene, which encodes a ligand for Notch family receptors. A characteristic feature of Alagille syndrome is intrahepatic bile duct paucity. We described previously that mice doubly heterozygous for Jag1 and Notch2 mutations are an excellent model for Alagille syndrome. However, our previous study did not establish whether bile duct paucity in Jag1/Notch2 double heterozygous mice resulted from impaired differentiation of bile duct precursor cells, or from defects in bile duct morphogenesis. METHODOLOGY/PRINCIPAL FINDINGS: Here we characterize embryonic biliary tract formation in our previously described Jag1/Notch2 double heterozygous Alagille syndrome model, and describe another mouse model of bile duct paucity resulting from liver-specific deletion of the Notch2 gene. CONCLUSIONS/SIGNIFICANCE: Our data support a model in which bile duct paucity in Notch pathway loss of function mutant mice results from defects in bile duct morphogenesis rather than cell fate specification

    Efficacy of Major Plant Extracts/Molecules on Field Insect Pests

    Get PDF
    Insect pests are considered the major hurdle in enhancing the production and productivity of any farming system. The use of conventional synthetic pesticides has led to the emergence of pesticide-resistant insects, environmental pollution, and negative effects on natural enemies, which have caused an ecological imbalance of the predator-prey ratio and human health hazards; therefore, eco-friendly alternative strategies are required. The plant kingdom, a rich repertoire of secondary metabolites, can be tapped as an alternative for insect pest management strategies. A number of plants have been documented to have insecticidal properties against various orders of insects in vitro by acting as antifeedants, repellents, sterilant and oviposition deterrents, etc. However, only a few plant compounds are applicable at the field level or presently commercialised. Here, we have provided an overview of the broad-spectrum insecticidal activity of plant compounds from neem, Annona, Pongamia, and Jatropha. Additionally, the impact of medicinal plants, herbs, spices, and essential oils has been reviewed briefl

    Neem (Azadirachta indica A. Juss): organisms affected and reference list update

    No full text
    Volume: 91Start Page: 367End Page: 38

    Adult house fly feeding deterrent from neem seeds /

    No full text
    ARR-NE-

    Azadirachta indica : a source of insect feeding inhibitors and growth regulators /

    No full text
    ARM-NE-
    corecore