1,027 research outputs found
Relations with the Third World: Views on the North-South Dialogue and Food Security - Canada
International Relations/Trade,
Sleep apnoea: prevalence in essential hypertension and effects on renal function
Imperial Users onl
Mar and Me: Following the Traces
AbstractIn this paper I will trace the influence that Marlene Kadar's scholarship has had on my own thinking, while making more general comments about personal writing and collaborative research as feminist practices. . Marlene and I, along with Jeanne Perreault and (for the first volume Susanna Egan) co-edited two books and one special issue of a journal together. But it was not until I read her essay for our first book, Tracing the Autobiographical (2005), that I really saw how much Kadar could stretch the idea of life writing even further and find even more lives, vulnerable lives, in the most unexpected places. Kadar adds traces and fragments to our understanding of autobiographical practices. The expansiveness of her thinking cuts a path for others to follow
A Comparison of the Elemental Concentrations in Tissue Thymocytes from Diabetic and Non-Diabetic Rats
The elemental concentrations in thymocytes from control and diabetic rats were studied by use of the techniques of cryofixation and X-ray microanalysis to determine whether any changes occur in the diseased state. Decreases in the concentrations of the elements P and K were found in thymocytes from the subcapsular and cortical regions of the gland in thymus tissue taken 4 days after the onset of diabetes. A decrease in the concentration of Mg was also found in thymocytes from the subcapsular region of the gland. These changes suggest that the metabolism of thymocytes in vivo is altered in the diabetic animals
Changes in Sodium Concentration in Cardiac Myocytes from Diabetic Rats
The effects of streptozotocin induced diabetes on rats were studied. The animals showed an increase in blood glucose concentration and a loss of weight from both the body and the heart. Loss of weight from the heart was less severe leading to an increased heart to body weight ratio. Study of element concentrations by X-ray microanalysis showed that there was an increase in intracellular Na concentration in cardiac myocytes from the diabetic animals, but no change in Mg. These results agree with studies which show changes in Na/K ATPase after the onset of diabetes
X-Ray Microanalysis of Cells in Suspension and the Application of this Technique to the Study of the Thymus Gland
Although X-ray microanalysis has become a well established technique in the study of tissues there are still relatively few papers reporting results from cells in culture. Our early investigations on freshly isolated murine thymocytes reported higher than expected concentrations of Na and Cl in these cells but subsequent studies have shown that these high concentrations are artefactual. Rat thymocytes that have been isolated and incubated for a short time to allow them to recover from the isolation procedure have lower concentrations of Na and Cl. Sections prepared from pellets of cells which have been concentrated by centrifugation in a microhaematocrit centrifuge have concentrations of Na and Cl which are within the range that has been described for thymocytes in tissues. This method of concentration can be applied successfully to the study of white cells from the peripheral blood. In diabetic animals pyknotic cells occur in the thymus. These cells are characterised by low concentrations of K but no rise in the concentration of Na. Study of thymocytes isolated from a diabetic animal also show pyknotic cells low in K confirming these observations
Locating the Subject of Post-Colonial Autobiography
Somewhat of a growth industry these days, theoretical formulations of the poetics of autobiography by and large continue to ignore post-colonial writings even though many of the texts emerging from these locations, particularly in the past twenty years, are \u27life-writings\u27 .1 Generally, EuroAmerican autobiography theory focuses on its own cosmopolitan space. Displaying an all too familiar geographic and ethnocentric bias, theory is made in the West and it speaks of the West. Because of this bias, theory tends to ignore the issue of place- that is, spatial and geographic location -as a constitutive element of the autobiographical \u271\u27. Where the \u27I\u27 is, theory says, doesn\u27t really matter. But this ignores the fact that literary texts are always deeply rooted in specific places and histories. It is my argument that spatial location is crucial to post-colonial autobiographical self-representation, and that the forgetting of the located ness of the subject speaks of an imperialist assumption of centrality that has never been possible for the post-colonial writer
Cells are Not Just Bags of Water: A Personal Appreciation of the Work of Dr. Brij L. Gupta and his Contribution to Biological X-Ray Microanalysis
This paper surveys the contribution made by the work of Dr. B.L. Gupta to the science of biological X-ray microanalysis. A brief biographical sketch of Brij\u27s early years is given, this is followed by considerations about the models for water transport across epithelia. The ultrastructural and histochemical studies carried out by Brij Gupta and colleagues are reviewed to introduce the historical need for the use of EPXMA for the study of ion and water transport in epithelia. The outstanding contribution made by Brij Gupta\u27s work in this field is outlined, and his understanding of the subcellular distribution ions in other cell types and in the pericellular environment is acknowledged
The Preparation of Cultured Cells for X-Ray Microanalysis
X-ray microanalysis of cells in culture is being used increasingly for the study of relationships between element (ion) content and cell function. There is, however, no one single method which can be used for the preparation of all different cell types for study by microanalysis. Cells in suspension are usually concentrated by centrifugation, before cryofixation, cryosectioning, and freeze drying. On the other hand cells grown as monolayers are more often studied as whole cell mounts, which are washed to remove the external medium before cryofixation and freeze drying. The alternative approach, sectioning of cell monolayers is rarely used. Some of the difficulties encountered in preparing and monolayers of smooth muscle cells for X-ray microanalysis are discussed here
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