An analysis of HCN observations of the Circumnuclear Disk at the galactic centre

The Circumnuclear Disk (CND) is a torus of dust and molecular gas rotating about the galactic centre and extending from approximately 1.6pc to 7pc from the central massive black hole, SgrA*. Large Velocity Gradient modelling of the intensities of the HCN 1-0, 3-2 and 4-3 transitions is used to infer hydrogen density and HCN optical depth. From HCN observations we find the molecular hydrogen density ranges from 0.1 to 2 $\times$ 10$^{6}$ cm$^{-3}$, about an order of magnitude less than inferred previously. The 1-0 line is weakly inverted with line-centre optical depth approx $-$0.1, in stark contrast to earlier estimates of 4. The estimated mass of the ring is approximately 3 $-$ 4 $\times$ 10$^{5}$M$_{\odot}$ consistent with estimates based on thermal dust emission. The tidal shear in the disk implies that star formation is not expected to occur without some significant triggering event.Comment: 17 pages, 8 figures, 7 tables (including 3 landscape tables generated with 2 separate Latex files

Accretion in giant planet circumplanetary disks

During the final growth phase of giant planets, accretion is thought to be controlled by a surrounding circumplanetary disk. Current astrophysical accretion disk models rely on hydromagnetic turbulence or gravitoturbulence as the source of effective viscosity within the disk. However, the magnetically-coupled accreting region in these models is so limited that the disk may not support inflow at all radii, or at the required rate. Here, we examine the conditions needed for self-consistent accretion, in which the disk is susceptible to accretion driven by magnetic fields or gravitational instability. We model the disk as a Shakura-Sunyaev $\alpha$ disk and calculate the level of ionisation, the strength of coupling between the field and disk using Ohmic, Hall and Ambipolar diffusevities for both an MRI and vertical field, and the strength of gravitational instability. We find that the standard constant-$\alpha$ disk is only coupled to the field by thermal ionisation within $30\,R_J$ with strong magnetic diffusivity prohibiting accretion through the bulk of the midplane. In light of the failure of the constant-$\alpha$ disk to produce accretion consistent with its viscosity we drop the assumption of constant-$\alpha$ and present an alternate model in which $\alpha$ varies radially according to the level magnetic turbulence or gravitoturbulence. We find that a vertical field may drive accretion across the entire disk, whereas MRI can drive accretion out to $\sim200\,R_J$, beyond which Toomre's $Q=1$ and gravitoturbulence dominates. The disks are relatively hot ($T\gtrsim800\,$K), and consequently massive ($M_{\text{disk}}\sim0.5\,M_J$).Comment: 19 pages, 5 figures, 2 tables; accepted for publication by MNRA

Magnetic fields in gaps surrounding giant protoplanets

Giant protoplanets evacuate a gap in their host protoplanetary disc, which gas must cross before it can be accreted. A magnetic field is likely carried into the gap, potentially influencing the flow. Gap crossing has been simulated with varying degrees of attention to field evolution (pure hydrodynamical, ideal, and resistive MHD), but as yet there has been no detailed assessment of the role of the field accounting for all three key non-ideal MHD effects: Ohmic resistivity, ambipolar diffusion, and Hall drift. We present a detailed investigation of gap magnetic field structure as determined by non-ideal effects. We assess susceptibility to turbulence induced by the magnetorotational instability, and angular momentum loss from large-scale fields. As full non-ideal simulations are computationally expensive, we take an a posteriori approach, estimating MHD quantities from the pure hydrodynamical gap crossing simulation by Tanigawa et al. (2012). We calculate the ionisation fraction and estimate field strength and geometry to determine the strength of non-ideal effects. We find that the protoplanetary disc field would be easily drawn into the gap and circumplanetary disc. Hall drift dominates, so that much of the gap is conditionally MRI unstable depending on the alignment of the field and disc rotation axes. Field alignment also influences the strong toroidal field component permeating the gap. Large-scale magnetic forces are small in the circumplanetary disc, indicating they cannot drive accretion there. However, turbulence will be key during satellite growth as it affects critical disc features, such as the location of the ice line.Comment: 14 pages, 6 figures, accepted for publication by MNRA

Food neophobia and mealtime food consumption in 4-5 year old children.

Background: Previous research has documented a negative association between maternal report of child food neophobia and reported frequency of consumption of fruit, vegetables, and meat. This study aimed to establish whether neophobia is associated with lower intake of these food types in naturalistic mealtime situations. Methods: One hundred and nine parents of 4–5 year olds completed questionnaires which included a six-item version of the Child Food Neophobia Scale (CFNS). The children took part in a series of 3 test lunch meals at weekly intervals at school at which they were presented with: chicken, cheese, bread, cheese crackers, chocolate biscuits, grapes and tomatoes or carrot sticks. Food items served to each child were weighed before and after the meal to assess total intake of items in four categories: Fruit and vegetables, Protein foods, Starchy foods and Snack foods. Pearson Product Moment Correlations and independent t tests were performed to examine associations between scores on the CFNS and consumption during lunches. Results: Neophobia was associated with lower consumption of fruit and vegetables, protein foods and total calories, but there was no association with intake of starch or snack foods. Conclusion: These results support previous research that has suggested that neophobia impacts differentially on consumption of different food types. Specifically it appears that children who score highly on the CFNS eat less fruit, vegetables and protein foods than their less neophobic peers. Attempts to increase intake of fruit, vegetables and protein might usefully incorporate strategies known to reduce the neophobic response

Development of the children's eating behaviour questionnaire

Individual differences in several aspects of eating style have been implicated in the development of weight problems in children and adults, but there are presently no reliable and valid scales that assess a range of dimensions of eating style. This paper describes the development and preliminary validation of a parent-rated instrument to assess eight dimensions of eating style in children; the Children's Eating Behaviour Questionnaire (CEBQ). Constructs for inclusion were derived both from the existing literature on eating behaviour in children and adults, and from interviews with parents. They included reponsiveness to food, enjoyment of food, satiety responsiveness, slowness in eating, fussiness, emotional overeating, emotional undereating, and desire for drinks. A. large pool of items covering each of these: constructs was developed. The number of items was then successively culled through analysis of responses from three samples of families of young children (N = 131; N = 187, N = 218), to produce a 35-item instrument with eight scales which were internally valid and had good test-retest reliability. Investigation of variations by gender and age revealed only minimal gender differences in any aspect of eating style. Satiety responsiveness and slowness in eating diminished from age 3 to 8. Enjoyment of food and food responsiveness increased over this age range. The CEBQ should provide a useful measure of eating style for research into the early precursors of obesity or eating disorders. This is especially important in relation to the growing evidence for the heritability of obesity, where good measurement of the associated behavioural phenotype will be crucial in investigating the contribution of inherited variations in eating behaviour to the process of weight gain

Reason to Ratify: The Influence of John Locke\u27s Religious Beliefs on the Creation and Adoption of the United States Constitution

The pervasive influence of Lockean religious convictions motivated the framers of the Constitution to establish a new form of government, provided the theoretical basis for the document itself, and inspired its popular ratification. Part II will lay the groundwork for this thesis by outlining Locke\u27s life and sources of his religious beliefs. Part III will undertake a more substantive examination of Locke\u27s opinions and the writings that memorialized them. Establishing how Lockean ideas of natural law, social contract, and reason are related to the inspiration, drafting, and acceptance of the Constitution takes place in Part IV, before the article\u27s conclusion in Part V

Reason to Ratify: The Influence of John Locke\u27s Religious Beliefs on the Creation and Adoption of the United States Constitution

The pervasive influence of Lockean religious convictions motivated the framers of the Constitution to establish a new form of government, provided the theoretical basis for the document itself, and inspired its popular ratification. Part II will lay the groundwork for this thesis by outlining Locke\u27s life and sources of his religious beliefs. Part III will undertake a more substantive examination of Locke\u27s opinions and the writings that memorialized them. Establishing how Lockean ideas of natural law, social contract, and reason are related to the inspiration, drafting, and acceptance of the Constitution takes place in Part IV, before the article\u27s conclusion in Part V

MOJAVE: Monitoring of Jets in AGN with VLBA Experiments. IV. The Parent Luminosity Function of Radio-Loud Blazars

(Abridged) We use a complete sample of active galactic nuclei (AGN) selected on the basis of relativistically beamed 15 GHz radio flux density to derive the parent radio luminosity function (RLF) of bright radio-selected blazar cores. We use a maximum likelihood method to fit a beamed RLF to the observed data and thereby recover the parameters of the intrinsic (unbeamed) RLF. We analyze two subsamples of the MOJAVE sample: the first contains only objects of known FR II class, with a total of 103 sources, and the second subsample adds 24 objects of uncertain FR class for a total of 127 sources. Both subsamples exclude four known FR I radio galaxies and two gigahertz-peaked spectrum sources. We obtain good fits to both subsamples using a single power law intrinsic RLF with pure density evolution function. We find that a previously reported break in the observed MOJAVE RLF actually arises from using incomplete bins (because of the luminosity cutoff) across a steep and strongly evolving RLF, and does not reflect a break in the intrinsic RLF. The derived space density of the parent population of the FR II sources from the MOJAVE sample (with L>1.3e25 W/Hz) is approximately 1600/Gpc^3.Comment: 31 pages, 7 figures and 2 tables. Accepted for publication in ApJ. Changes: classification of sources based on radio morphology instead of optical classes; added the parameters of the RLF of the FR II sources; added more explanations; added a table listing the sample sources; added 2 extra figures related to the observed break in the RLF; updated reference

The impact of N-3 pufa ingestion on metabolic, molecular and epigenetic responses to a short-term high-fat diet

Obesity is widely considered a primary risk factor for type 2 diabetes (T2D). However, less is known about the early adaptive responses to short-term periods of high-fat energy excess (HFEE). Previous reports detailing whole-body adaptation to fat and energy oversupply are equivocal, perhaps, in part, owing to use of different experimental protocols, varying durations of dietary manipulation and participant cohorts with individuals of varying characteristics. In addition to use of different dietary protocols between studies, alterations in functional end-point measures due to the type of dietary fat consumed warrants consideration. Daily n-3 PUFA intake, commonly obtained from pelagic fish oil (FO) consumption, has been shown to positively associate with insulin sensitivity in epidemiological studies and thus may be a useful dietary strategy for slowing insulin resistance development. Chapter 2 of this thesis extends previous literature by demonstrating that 6 d HFEE (150 % habitual energy intake; 60 % of energy from fat) does not clearly alter whole- body insulin sensitivity, irrespective of FO consumption. However, investigation of metabolism at the tissue level, as presented in Chapter 3 of this thesis, offers insight into a potential tissue-specific level of regulation that precedes whole-body regulation. Skeletal muscle insulin signalling protein (e.g. protein kinase B (PKB)) activity, levels of certain ceramide species, and AMPK α2 activity were altered following HFEE and may explain the early maladaptive responses to short-term HFEE. Moreover, FO intake as 10 % of total fats mediated some of these molecular Sophie Wardle: Ph.D. Thesis ii responses, including PKB and AMPK α2 activity, reflecting possible functional effects of FO at the subcellular level. Regulation of these metabolic / molecular responses at both the tissue and whole- body level can be explained, in part, by genetic predisposition, environmental influence and more recently epigenetics, including microRNAs (miRNAs). In Chapter 4, we characterised the plasma and skeletal muscle miRNA responses to HFEE and oral glucose ingestion. We demonstrate transient changes in levels of certain miRNAs following oral glucose ingestion in both tissue types and in response to HFEE in skeletal muscle. However, no significant correlations between basal plasma and skeletal muscle miRNA levels were observed, suggesting that our candidate plasma miRNAs may be co-ordinating functional changes in other tissue types. Plasma miR- 145-5p and skeletal muscle miR-204-5p predicted a significant proportion of the variance in mean whole-body insulin sensitivity change in response to HFEE. These data indicate that these miRNAs may be useful biomarkers of insulin resistance development following HFEE. A constraint of this thesis is that all conclusions are made within the context of statistically unaltered insulin sensitivity. Therefore, future investigations of diet- induced maladaptation should consider establishing a time course of insulin resistance development in response to HFEE, or use different study populations. Populations that are more susceptible to T2D development, e.g., overweight, sedentary individuals would be of particular interest. These data would aid development of a working model of diet-induced insulin resistance that has more direct application to T2D progression and extends the data presented herein