Graph Neural Network Based Method for Path Planning Problem

Sampling-based path planning is a widely used method in robotics, particularly in high-dimensional state space. Among the whole process of the path planning, collision detection is the most time-consuming operation. In this paper, we propose a learning-based path planning method that aims to reduce the number of collision detection. We develop an efficient neural network model based on Graph Neural Networks (GNN) and use the environment map as input. The model outputs weights for each neighbor based on the input and current vertex information, which are used to guide the planner in avoiding obstacles. We evaluate the proposed method's efficiency through simulated random worlds and real-world experiments, respectively. The results demonstrate that the proposed method significantly reduces the number of collision detection and improves the path planning speed in high-dimensional environments

Antibiotic Stewardship in Retail Pharmacies and the Access-Excess Challenge in China:A Policy Review

In China, efforts to restrict excessive antibiotic consumption may prevent sufficient access to these life-saving drugs among the most deprived in society because of the weak primary health care system. This makes antibiotic stewardship in the retail pharmacy sector a particular challenge. We conducted an analysis to examinate policies on antibiotic sales in retail pharmacies in China and how tensions between ‘excess’ and ‘access’ are managed. The analysis was guided by the Walt and Gilson health policy analysis triangle to systematically analyse policies based on the content of policies, contexts, governance processes, and actors. Nine research studies and 25 documents identified from national and international sources were extracted, grouped into categories, and examined within and across records and categories. As of 2020, eight key policies have been introduced in China that focus on two areas: dispending prescribed medicines or antimicrobials with a prescription and having a licensed pharmacist present in the retail pharmacies, with approaches having changed over time. Inappropriate sales of antibiotics are still common in retail pharmacies, which can be linked to the lack of consistency and enforcement of published policies, the profit-driven nature of retail pharmacies, and the displacement of the demand for antibiotics from clinical into less regulated settings

Inpatient care burden due to cancers in Anhui, China: a cross-sectional household survey

Raw dataset of inpatient cancer care costs and related variables studied. (XLSX 32 kb

Diagnosis of Primary Acinic Cell Carcinoma of the Lung Using CT: A Case Analysis

Acinic cell carcinoma (ACC) is a malignant epithelial salivary gland neoplasm that most frequently occurs in the salivary glands. However, primary ACC of the lung is extremely rare. Due to its low incidence and the lack of related literature, clinicians lack relevant knowledge. It is prone to misdiagnosis, which delays the treatment of patients. Thus, we report a case of primary ACC of the lung confirmed via surgery and pathology, together with a review of relevant literature, in order to summarize the CT imaging manifestations and the value of CT in the diagnosis and treatment of this disease. The aim of this case report was to improve the understanding of primary ACC of the lung and to improve the diagnostic abilities

High-quality genome assembly and comparative genomic profiling of yellowhorn (Xanthoceras sorbifolia) revealed environmental adaptation footprints and seed oil contents variations

Yellowhorn (Xanthoceras sorbifolia) is a species of deciduous tree that is native to Northern and Central China, including Loess Plateau. The yellowhorn tree is a hardy plant, tolerating a wide range of growing conditions, and is often grown for ornamental purposes in parks, gardens, and other landscaped areas. The seeds of yellowhorn are edible and contain rich oil and fatty acid contents, making it an ideal plant for oil production. However, the mechanism of its ability to adapt to extreme environments and the genetic basis of oil synthesis remains to be elucidated. In this study, we reported a high-quality and near gap-less yellowhorn genome assembly, containing the highest genome continuity with a contig N50 of 32.5 Mb. Comparative genomics analysis showed that 1,237 and 231 gene families under expansion and the yellowhorn-specific gene family NB-ARC were enriched in photosynthesis and root cap development, which may contribute to the environmental adaption and abiotic stress resistance of yellowhorn. A 3-ketoacyl-CoA thiolase (KAT) gene (Xso_LG02_00600) was identified under positive selection, which may be associated with variations of seed oil content among different yellowhorn cultivars. This study provided insights into environmental adaptation and seed oil content variations of yellowhorn to accelerate its genetic improvement

How patients’ experiences of respiratory tract infections affect healthcare-seeking and antibiotic use::insights from a cross-sectional survey in rural Anhui, China

ObjectiveTo investigate the occurrence of reported respiratory tract infection (RTI) symptoms and their effects on use of self and professional care among patients in the community.DesignA cross-sectional retrospective household survey.Setting12 administrative villages from rural Anhui, China.Participants2160 rural adult residents aged ≥18 years registered as rural residents and actually living in the sampled villages when this study was conducted.MethodThe respondents were recruited using stratified-clustered randomised sampling. A structured questionnaire was deployed to solicit information about social demographics, symptoms of last RTI and healthcare-seeking following the RTI. Descriptive analyses were performed to investigate the reported symptoms, and multivariate logistic regression models were developed to identify relationships between number of concurrent symptoms and healthcare-seeking and antibiotics use.ResultsA total of 1968 residents completed the survey, resulting in a response rate of 91.1%. The number of concurrent symptoms showed a clear increasing trend with seeking help from clinics and being prescribed antibiotics. Multivariate regression revealed statistically significant associations between the following: (a) visiting clinics and education (OR=0.790), sore throat (OR=1.355), cough (OR=1.492), shortness of breath (OR=1.707) and fever (OR=2.142); (b) buying medicine from shops without prescription and education (OR=1.230) and cough (OR=1.452); (c) getting antibiotics at clinics and sore throat (OR=2.05) and earache and/or tinnitus (OR=4.884); and (d) obtaining antibiotics at medicine shops and productive cough (OR=1.971).ConclusionsReported RTI symptoms play an important role in shaping both patient- and doctor-led responses.</jats:sec