Experience, tenure and gender wage difference: evidence from China

This paper studies the returns to general labour market experience and firm-specific tenure, using data from China. Specifically, it focuses on explaining the gender wage difference from the perspective of general human capital and specific human capital. It applies the Heckman maximum likelihood estimator and Topel two-step estimation methodology to correct sample selection bias and individual heterogeneity. After correcting the errors, the authors find that returns to experience are higher for men than women, especially for married men and women. Furthermore, the return to tenure is higher than that to general experience. For men, the former is about 6% higher than the latter. But for women, tenure contributes 7–8% more to the wage growth than experience. The return of general experience mainly contributes to gender wage difference in China. Empirical results also show that the cross section analysis downward biases the returns to potential experience and a simple Topel-2S estimation in the panel study upward biases the return

A Study on the Critical Thinking Disposition of English Major Students -- A Case Study of Undergraduate English Majors at S University

This article focuses on undergraduate English majors at S University as research subjects, using the Chinese revised version of the California Critical Thinking Disposition Inventory (CTDI-CV) by Peng Meici. Using SPSS 26.0, the study analyzed the current status of critical thinking disposition among S University students and the differences in scores among different groups. The following conclusions were drawn: Overall, the critical thinking disposition of S University undergraduate English majors is at a moderate to high level, and there are varying degrees of differences among different student groups in terms of gender, parents’ education level, grade, high school type, and whether they have taken the “English Speech and Debate” course. Based on these survey results, corresponding suggestions are provided

STUDY ON ARRANGEMENT OF COOLING WATER PIPE TO CONTROL HYDRATION HEAT OF CONCRETE IN BEAM OF CABLE-STAYED BRIDGE

The box girder joint section of the Yangtze River Highway Bridge is taken as the research background, and the finite element software MIDAS/FEA is used to simulate the hydration heat of concrete to the layout of cooling water pipe in building mass concrete. The finite element calculation results are in well agreement with the measured data. On this basis, the influence of changing the diameter and distance of the cooling water pipe, the inlet temperature and the flow rate on the temperature of hydration heat is studied. The results show diameter of the cooling water pipe and inlet temperature have a significant effect on the temperature of hydration heat. The change of water flow rate has little effect on the temperature of hydration heat. It provides a reference for the layout of the same concrete cooling water pipe arrangement

Curriculum Knowledge Switching for Pancreas Segmentation

Pancreas segmentation is challenging due to the small proportion and highly changeable anatomical structure. It motivates us to propose a novel segmentation framework, namely Curriculum Knowledge Switching (CKS) framework, which decomposes detecting pancreas into three phases with different difficulty extent: straightforward, difficult, and challenging. The framework switches from straightforward to challenging phases and thereby gradually learns to detect pancreas. In addition, we adopt the momentum update parameter updating mechanism during switching, ensuring the loss converges gradually when the input dataset changes. Experimental results show that different neural network backbones with the CKS framework achieved state-of-the-art performance on the NIH dataset as measured by the DSC metric.Comment: ICIP 202

A Novel Strategy of US3 Codon De-Optimization for Construction of an Attenuated Pseudorabies Virus against High Virulent Chinese Pseudorabies Virus Variant

In this study, we applied bacterial artificial chromosome (BAC) technology with PRVΔTK/gE/gI as the base material to replace the first, central, and terminal segments of the US3 gene with codon-deoptimized fragments via two-step Red-mediated recombination in E. coli GS1783 cells. The three constructed BACs were co-transfected with gI and part of gE fragments carrying homologous sequences (gI+gE’), respectively, in swine testicular cells. These three recombinant viruses with US3 codon de-optimization ((PRVΔTK&gE-US3deop−1, PRVΔTK&gE-US3deop−2, and PRVΔTK&gE-US3deop−3) were obtained and purified. These three recombinant viruses exhibited similar growth kinetics to the parental AH02LA strain, stably retained the deletion of TK and gE gene fragments, and stably inherited the recoded US3. Mice were inoculated intraperitoneally with the three recombinant viruses or control virus PRVΔTK&gEAH02 at a 107.0 TCID50 dose. Mice immunized with PRVΔTK&gE-US3deop−1 did not develop clinical signs and had a decreased virus load and attenuated pathological changes in the lungs and brain compared to the control group. Moreover, immunized mice were challenged with 100 LD50 of the AH02LA strain, and PRVΔTK&gE-US3deop−1 provided similar protection to that of the control virus PRVΔTK&gEAH02. Finally, PRVΔTK&gE-US3deop−1 was injected intramuscularly into 1-day-old PRV-negative piglets at a dose of 106.0 TCID50. Immunized piglets showed only slight temperature reactions and mild clinical signs. However, high levels of seroneutralizing antibody were produced at 14 and 21 days post-immunization. In addition, the immunization of PRVΔTK&gE-US3deop−1 at a dose of 105.0 TCID50 provided complete clinical protection and prevented virus shedding in piglets challenged by 106.5 TCID50 of the PRV AH02LA variant at 1 week post immunization. Together, these findings suggest that PRVΔTK&gE-US3deop−1 displays great potential as a vaccine candidate

Blue-Sky Albedo Reduction and Associated Influencing Factors of Stable Land Cover Types in the Middle-High Latitudes of the Northern Hemisphere during 1982–2015

Land surface albedo (LSA) directly affects the radiation balance and the surface heat budget. LSA is a key variable for local and global climate research. The complexity of LSA variations and the driving factors highlight the importance of continuous spatial and temporal monitoring. Snow, vegetation and soil are the main underlying surface factors affecting LSA dynamics. In this study, we combined Global Land Surface Satellite (GLASS) products and ERA5 reanalysis products to analyze the spatiotemporal variation and drivers of annual mean blue-sky albedo for stable land cover types in the middle-high latitudes of the Northern Hemisphere (30~90°N) from 1982 to 2015. Snow cover (SC) exhibited a decreasing trend in 99.59% of all pixels (23.73% significant), with a rate of −0.0813. Soil moisture (SM) exhibited a decreasing trend in 85.66% of all pixels (22.27% significant), with a rate of −0.0002. The leaf area index (LAI) exhibited a greening trend in 74.38% of all pixels (25.23% significant), with a rate of 0.0014. Blue-sky albedo exhibited a decreasing trend in 98.97% of all pixels (65.12% significant), with a rate of −0.0008 (OLS slope). Approximately 98.16% of all pixels (57.01% significant) exhibited a positive correlation between blue-sky albedo and SC. Approximately 47.78% and 67.38% of all pixels (17.13% and 25.3% significant, respectively) exhibited a negative correlation between blue-sky albedo and SM and LAI, respectively. Approximately 10.31%, 20.81% and 68.88% of the pixel blue-sky albedo reduction was mainly controlled by SC, SM and LAI, respectively. The decrease in blue-sky albedo north of 40°N was mainly caused by the decrease in SC. The decrease in blue-sky albedo south of 40°N was mainly caused by SM reduction and vegetation greening. The decrease in blue-sky albedo in the western Tibetan Plateau was caused by vegetation greening, SM increase and SC reduction. The results have important scientific significance for the study of surface processes and global climate change

Different patterns of foreground and background processing contribute to texture segregation in humans: an electrophysiological study

Background Figure-ground segregation is a necessary process for accurate visual recognition. Previous neurophysiological and human brain imaging studies have suggested that foreground-background segregation relies on both enhanced foreground representation and suppressed background representation. However, in humans, it is not known when and how foreground and background processing play a role in texture segregation. Methods To answer this question, it is crucial to extract and dissociate the neural signals elicited by the foreground and background of a figure texture with high temporal resolution. Here, we combined an electroencephalogram (EEG) recording and a temporal response function (TRF) approach to specifically track the neural responses to the foreground and background of a figure texture from the overall EEG recordings in the luminance-tracking TRF. A uniform texture was included as a neutral condition. The texture segregation visual evoked potential (tsVEP) was calculated by subtracting the uniform TRF from the foreground and background TRFs, respectively, to index the specific segregation activity. Results We found that the foreground and background of a figure texture were processed differently during texture segregation. In the posterior region of the brain, we found a negative component for the foreground tsVEP in the early stage of foreground-background segregation, and two negative components for the background tsVEP in the early and late stages. In the anterior region, we found a positive component for the foreground tsVEP in the late stage, and two positive components for the background tsVEP in the early and late stages of texture processing. Discussion In this study we investigated the temporal profile of foreground and background processing during texture segregation in human participants at a high time resolution. The results demonstrated that the foreground and background jointly contribute to figure-ground segregation in both the early and late phases of texture processing. Our findings provide novel evidence for the neural correlates of foreground-background modulation during figure-ground segregation in humans

Angle dependent field-driven reorientation transitions in uniaxial antiferromagnet MnBi2_2Te4_4 single crystal

MnBi$_2$Te$_4$, a two-dimensional magnetic topological insulator with a uniaxial antiferromagnetic structure, is an ideal platform to realize quantum anomalous Hall effect. However, the strength of magnetic interactions is not clear yet. We performed systematic studies on the magnetization and angle dependent magnetotransport of MnBi$_2$Te$_4$ single crystal. The results show that the direction of the magnetic field has significant effects on the critical field values and magnetic structure of this compound, which leads to different magnetotransport behaviors. The field-driven reorientation transitions can be utilized to estimate the AFM interlayer exchange interaction coupling and uniaxial magnetic anisotropy D. The obtained Hamiltonian can well explain the experimental data by Monte Carlo simulations. Our comprehensive studies on the field-driven magnetic transitions phenomenon in MnBi$_2$Te$_4$ provide a general approach for other topological systems with antiferromagnetism.Comment: 6 figure

Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress

Silica nanoparticles (SiO2 NPs) cause oxidative stress in respiratory system. Meanwhile, human cells launch adaptive responses to overcome SiO2 NP toxicity. However, besides a few examples, the regulation of SiO2 NP-responsive proteins and their functions in SiO2 NP response remain largely unknown. In this study, we demonstrated that SiO2 NP induced the expression of follistatin (FST), a stress responsive gene, in mouse lung tissue as well as in human lung epithelial cells (A549). The levels of Ac-H3(K9/18) and H3K4me2, two active gene markers, at FST promoter region were significantly increased during SiO2 NP treatment. The induction of FST transcription was mediated by the nuclear factor erythroid 2-related factor 2 (Nrf2), as evidenced by the decreased FST expression in Nrf2-deficient cells and the direct binding of Nrf2 to FST promoter region. Down-regulation of FST promoted SiO2 NP-induced apoptosis both in cultured cells and in mouse lung tissue. Furthermore, knockdown of FST increased while overexpression of FST decreased the expression level of NADPH oxidase 1 (NOX1) and NOX5 as well as the production of cellular reactive oxygen species (ROS). Taken together, these findings demonstrated a protective role of FST in SiO2 NP-induced oxidative stress and shed light on the interaction between SiO2 NPs and biological systems