DIVOTrack: A Novel Dataset and Baseline Method for Cross-View Multi-Object Tracking in DIVerse Open Scenes

Cross-view multi-object tracking aims to link objects between frames and camera views with substantial overlaps. Although cross-view multi-object tracking has received increased attention in recent years, existing datasets still have several issues, including 1) missing real-world scenarios, 2) lacking diverse scenes, 3) owning a limited number of tracks, 4) comprising only static cameras, and 5) lacking standard benchmarks, which hinder the investigation and comparison of cross-view tracking methods. To solve the aforementioned issues, we introduce DIVOTrack: a new cross-view multi-object tracking dataset for DIVerse Open scenes with dense tracking pedestrians in realistic and non-experimental environments. Our DIVOTrack has ten distinct scenarios and 550 cross-view tracks, surpassing all cross-view multi-object tracking datasets currently available. Furthermore, we provide a novel baseline cross-view tracking method with a unified joint detection and cross-view tracking framework named CrossMOT, which learns object detection, single-view association, and cross-view matching with an all-in-one embedding model. Finally, we present a summary of current methodologies and a set of standard benchmarks with our DIVOTrack to provide a fair comparison and conduct a comprehensive analysis of current approaches and our proposed CrossMOT. The dataset and code are available at https://github.com/shengyuhao/DIVOTrack

Caspase polymorphisms and prognosis of hepatocellular carcinoma

The aim of our study was to determine the impact of genetic polymorphisms in the caspase (CASP) genes on prognosis of hepatocellular carcinoma (HCC). We genotyped 7 potentially functional polymorphisms in CASP3, CASP7, CASP8, CASP9, CASP10 genes in 362 HCC patients of receiving surgical resection of HCC tumor. The associations of genotype and haplotype with overall survival (OS) and disease free survival (DFS) were analyzed by using the Cox proportional hazards model. We found that the CASP9 rs4645981 C allele was significantly associated with positive effect on DFS (P = 0.011 and 0.016 for CT+CC vs. TT in univariate and multivariate analysis, respectively), CT genotype was associated with a better OS of HCC than the TT genotype both in univariate and multivariate analysis (P = 0.048 and 0.041, respectively). Moreover, the CASP3 rs2705897 GT genotype showed marginally significant association with decreased OS and DFS, compared with the GG genotype. One haplotype TT/TG in CASP3 (constructed by rs12108497 T>C and rs2705897 T>G) was significantly associated with decreased OS and DFS, compared to the common haplotype TT/TT both in univariate analysis (P = 0.021 and 0.026, respectively) and multivariate analysis (P = 0.025 and 0.030, respectively). The haplotype GT/GT in CASP9 (constructed by rs4645978 A>G and rs4645981 C>T) was significantly associated with decreased DFS both in univariate and multivariate analysis (P = 0.012 and 0.010, respectively). In conclusion, the CASP9 rs4645981 polymorphism, CASP3 and CASP9 haplotypes may be useful prognosis markers for HCC patients with surgical resection of tumor

Mesaconine alleviates doxorubicin-triggered cardiotoxicity and heart failure by activating PINK1-dependent cardiac mitophagy

Aberrant mitophagy has been identified as a driver for energy metabolism disorder in most cardiac pathological processes. However, finding effective targeted agents and uncovering their precise modulatory mechanisms remain unconquered. Fuzi, the lateral roots of Aconitum carmichaelii, shows unique efficacy in reviving Yang for resuscitation, which has been widely used in clinics. As a main cardiotonic component of Fuzi, mesaconine has been proven effective in various cardiomyopathy models. Here, we aimed to define a previously unrevealed cardioprotective mechanism of mesaconine-mediated restoration of obstructive mitophagy. The functional implications of mesaconine were evaluated in doxorubicin (DOX)-induced heart failure models. DOX-treated mice showed characteristic cardiac dysfunction, ectopic myocardial energy disorder, and impaired mitophagy in cardiomyocytes, which could be remarkably reversed by mesaconine. The cardioprotective effect of mesaconine was primarily attributed to its ability to promote the restoration of mitophagy in cardiomyocytes, as evidenced by elevated expression of PINK1, a key mediator of mitophagy induction. Silencing PINK1 or deactivating mitophagy could completely abolish the protective effects of mesaconine. Together, our findings suggest that the cardioprotective effects of mesaconine appear to be dependent on the activation of PINK1-induced mitophagy and that mesaconine may constitute a promising therapeutic agent for the treatment of heart failure

From BASE-ASIA Toward 7-SEAS: A Satellite-Surface Perspective of Boreal Spring Biomass-Burning Aerosols and Clouds in Southeast Asia

In this paper, we present recent field studies conducted by NASA's SMART-COMMIT (and ACHIEVE, to be operated in 2013) mobile laboratories, jointly with distributed ground-based networks (e.g., AERONET, http://aeronet.gsfc.nasa.gov/ and MPLNET, http://mplnet.gsfc.nasa.gov/) and other contributing instruments over northern Southeast Asia. These three mobile laboratories, collectively called SMARTLabs (cf. http://smartlabs.gsfc.nasa.gov/, Surface-based Mobile Atmospheric Research & Testbed Laboratories) comprise a suite of surface remote sensing and in-situ instruments that are pivotal in providing high spectral and temporal measurements, complementing the collocated spatial observations from various Earth Observing System (EOS) satellites. A satellite-surface perspective and scientific findings, drawn from the BASE-ASIA (2006) field deployment as well as a series of ongoing 7-SEAS (2010-13) field activities over northern Southeast Asia are summarized, concerning (i) regional properties of aerosols from satellite and in situ measurements, (ii) cloud properties from remote sensing and surface observations, (iii) vertical distribution of aerosols and clouds, and (iv) regional aerosol radiative effects and impact assessment. The aerosol burden over Southeast Asia in boreal spring, attributed to biomass burning, exhibits highly consistent spatial and temporal distribution patterns, with major variability arising from changes in the magnitude of the aerosol loading mediated by processes ranging from large-scale climate factors to diurnal meteorological events. Downwind from the source regions, the tightly coupled-aerosolecloud system provides a unique, natural laboratory for further exploring the micro- and macro-scale relationships of the complex interactions. The climatic significance is presented through large-scale anti-correlations between aerosol and precipitation anomalies, showing spatial and seasonal variability, but their precise cause-and-effect relationships remain an open-ended question. To facilitate an improved understanding of the regional aerosol radiative effects, which continue to be one of the largest uncertainties in climate forcing, a joint international effort is required and anticipated to commence in springtime 2013 in northern Southeast Asia

Ionic [Ru] complex with recyclability by electro-adsorption for efficient catalytic transfer hydrogenation of aryl ketones

The efficient reuse of homogeneous catalyst is important. Cation complex of [Ru(η6-p-cymene)(PPh3)(CH3CN) Cl]PF6 with different ligands was synthesized and characterized by infrared spectroscopy (IR), 1H-, 13C- and 31P-nuclear magnetic resonance spectroscopy (1H-, 13C- and 31P-NMR), element analysis (EA), and high resolution mass spectrometry (HR-MS). The complex was used as a catalyst for the hydrogen transfer reduction of carbonyl for the first time, presenting an excellent catalytic performance of 89%–98% conversion of acetophenone and its derivatives. The catalyst may be efficiently reused by the electro-adsorption of 10 times to one catalyst recovery. The cation [Ru] complex presented advantages of both homogeneous and heterogeneous catalysts

Condensation heat transfer and pressure drop characteristics of R-134a in horizontal smooth tubes and enhanced tubes fabricated by selective laser melting

This paper reports a study of condensation heat transfer and pressure drop of R134a inside four enhanced tubes and one plain tube fabricated by Selective Laser Melting (SLM). The results are compared to a plain commercial aluminum tube. The enhanced tubes consist of a tube with a metallic foam structure, a tube with eight short circumferential pin fins, a tube with five long circumferential pin fins and a tube with five twisted pin fins. The experiments were conducted at mass fluxes from 50 to 150 kg/m2 s. Throughout the experiments, the inlet and outlet vapor qualities were maintained at 0.9 and 0.3, respectively. Two saturation pressures of 13.4 bar and 11.6 bar were investigated. The effects of fin height, refrigerant flow direction and mass flux on the heat transfer coefficient and pressure drop were studied. Our results show that for the wavy flow pattern, the saturation pressure, vapor quality, mass flux, refrigerant flow direction and fin structure have significant effects on the condensation heat transfer coefficient and pressure drop. At higher saturation pressures, the head impact on the fins with shorter fin height has a higher heat transfer coefficient than the back impact. For the longer and twisted fins, a reversed trend was observed. With an increase in the mass flux or a decrease in the saturation pressure, the difference in heat transfer coefficients between the head and back impact for the same tube structure reduces. The heat transfer coefficients of the metallic foam tubes are higher than that of the plain SLM tube with a large penalty of pressure drop. The eight-fin tubes yield higher efficiency indices in terms of heat transfer over pressure drop when compared to the other tubes.NRF (Natl Research Foundation, S’pore)Accepted versio