An intelligent bearing fault diagnosis method based on the AFEEMD and 1D CNNs

To process the non-stationary vibration signals and improve accuracy of bearing fault diagnosis, this paper presents a novel intelligent fault diagnosis method based on the adaptive fast ensemble empirical mode decomposition (AFEEMD) and one-dimensional convolutional neural networks (1D CNNs). First, the AFEEMD algorithm is utilized to decompose the raw signals into intrinsic mode functions (IMFs). Then, the time and frequency statistic features of the first several IMFs are analyzed to form feature vector, which are used as the input of 1D CNNs to identify the bearing fault. The performance of the proposed method is validated using the dataset from the Case Western Reserve University (CWRU). Compared with the traditional back propagation neural network (BPNN), the results show that the proposed AFEEMD-1D CNNs method not only can obtain higher accuracy and achieve more reliable performance, but also can improve the generalization performance. Due to the end-to-end feature learning capacity, it can be extended to other machinery for fault diagnosis

Research on sampling of vibration signals based on compressed sensing

Oversampling is used at traditional signal processing, but with the big data developing, oversampling has the disadvantages that do not meet the high-volume and high-velocity, so we apply the theory of compressed sensing to sample mechanical vibration signals with undersampling, and get the better observation matrix and reconstruction algorithm which are suitable for the vibration signal. The reconstruction error is quantified by the numerical simulation. The comparison results of the time and frequency domain before and after signal reconstruction are carried out. The simulation results show when the sampling frequency is one fifth of the traditional sampling frequency, the error of the characteristic parameters between the original signal and reconstruction signal is less than 7 % in the time domain, and the main frequency components of the reconstruction signal do not change in the frequency domain, which can meet the engineering applications

The Solution Set Characterization and Error Bound for the Extended Mixed Linear Complementarity Problem

For the extended mixed linear complementarity problem EML CP , we first present the characterization of the solution set for the EMLCP. Based on this, its global error bound is also established under milder conditions. The results obtained in this paper can be taken as an extension for the classical linear complementarity problems

Global Error Bound Estimation for the Generalized Nonlinear Complementarity Problem over a Closed Convex Cone

The global error bound estimation for the generalized nonlinear complementarity problem over a closed convex cone (GNCP) is considered. To obtain a global error bound for the GNCP, we first develop an equivalent reformulation of the problem. Based on this, a global error bound for the GNCP is established. The results obtained in this paper can be taken as an extension of previously known results

Enhancement of recombinant myricetin on the radiosensitivity of lung cancer A549 and H1299 cells

OBJECTIVE: Myricetin, a common dietary flavonoid is widely distributed in fruits and vegetables, and is used as a health food supplement based on its immune function, anti-oxidation, anti-tumor, and anti-inflammatory properties. The aim of this study was to investigate the effects of myricetin on combination with radiotherapy enhance radiosensitivity of lung cancer A549 and H1299 cells. METHODS: A549 cells and H1299 cells were exposed to X-ray with or without myricetin treatment. Colony formation assays, CCK-8 assay, flow cytometry and Caspase-3 level detection were used to evaluate the radiosensitization activity of myricetin on cell proliferation and apoptosis in vitro. Nude mouse tumor xenograft model was built to assessed radiosensitization effect of myricetin in vivo. RESULTS: Compared with the exposed group without myricetin treatment, the groups treated with myricetin showed significantly suppressed cell surviving fraction and proliferation, increased the cell apoptosis and increased Caspase-3 protein expression after X-ray exposure in vitro. And in vivo assay, growth speed of tumor xenografts was significantly decreased in irradiated mice treated with myricetin. CONCLUSIONS: The study demonstrated both in vitro and in vivo evidence that combination of myricetin with radiotherapy can enhance tumor radiosensitivity of pulmonary carcinoma A549 and H1299 cells, and myricetin could be a potential radiosensitizer for lung cancer therapy. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/579151800121063

Geology-engineering integration to improve drilling speed and safety in ultra-deep clastic reservoirs of the Qiulitage structural belt

The Qiulitage structural belt in Tarim Basin has a large reservoir burial depth and complex geological conditions. Challenges such as ultra-depth, high temperature, high pressure and high stress lead to significant problems related to well control safety and project efficiency. To solve these key technical issues that set barriers to the process of exploration and development, a drilling technology process via the integration of geology and engineering was established with geomechanics as the bridge. An integrated key drilling engineering technology was formed for improving the drilling speed and safety of ultra-deep wells, including well location optimization, well trajectory optimization, formation pressure prediction before drilling, stratum drillability evaluation, and bit and speed-up tool design and optimization. Combined with the seismic data, logging data, structural characteristics, and lithology distribution characteristics, a rock mechanics data volume related to the three-dimensional drilling resistance characteristics of the block was established for the first time. The longitudinal and lateral heterogeneities were quantitatively characterized, providing a basis for bit design, improvement and optimization. During the drilling process, the geomechanical model was corrected in time according to the actual drilling information, and the drilling “three pressures” data were updated in real time to support the dynamic adjustment of drilling parameters. Through field practice, the average drilling complexity rate was reduced from 18% to 4.6%, and the drilling cycle at 8,500 m depth was reduced from 326 days to 257 days, which comprised significant improvements compared to the vertical wells deployed in the early stage without considering geology-engineering integration.Cited as: Chen, C., Ji, G., Wang, H., Huang, H., Baud, P., Wu, Q. Geology-engineering integration to improve drilling speed and safety in ultra-deep clastic reservoirs of the Qiulitage structural belt. Advances in Geo-Energy Research, 2022, 6(4): 347-356. https://doi.org/10.46690/ager.2022.04.0

Overexpression of AtBMI1C, a Polycomb Group Protein Gene, Accelerates Flowering in Arabidopsis

Polycomb group protein (PcG)-mediated gene silencing is emerging as an essential developmental regulatory mechanism in eukaryotic organisms. PcGs inactivate or maintain the silenced state of their target chromatin by forming complexes, including Polycomb Repressive Complex 1 (PRC1) and 2 (PRC2). Three PRC2 complexes have been identified and characterized in Arabidopsis; of these, the EMF and VRN complexes suppress flowering by catalyzing the trimethylation of lysine 27 on histone H3 of FLOWER LOCUS T (FT) and FLOWER LOCUS C (FLC). However, little is known about the role of PRC1 in regulating the floral transition, although AtRING1A, AtRING1B, AtBMI1A, and AtBMI1B are believed to regulate shoot apical meristem and embryonic development as components of PRC1. Moreover, among the five RING finger PcGs in the Arabidopsis genome, four have been characterized. Here, we report that the fifth, AtBMI1C, is a novel, ubiquitously expressed nuclear PcG protein and part of PRC1, which is evolutionarily conserved with Psc and BMI1. Overexpression of AtBMI1C caused increased H2A monoubiquitination and flowering defects in Arabidopsis. Both the suppression of FLC and activation of FT were observed in AtBMI1C-overexpressing lines, resulting in early flowering. No change in the H3K27me3 level in FLC chromatin was detected in an AtBMI1C-overexpressing line. Our results suggest that AtBMI1C participates in flowering time control by regulating the expression of FLC; moreover, the repression of FLC by AtBMI1C is not due to the activity of PRC2. Instead, it is likely the result of PRC1 activity, into which AtBMI1C is integrated

Seismic performance of horizontal swivel system of asymmetric continuous girder bridge

The bridge horizontal swivel system generally adopts a symmetrical structure and uses a spherical hinge structure that can adjust the rotation to complete rotation construction. Because of the complexity of railway lines under bridges, some asymmetrical horizontal swivel systems have been increasingly applied in practical engineering in recent years. This system is more suitable for areas with complex railway lines, reduces the bridge span, and provides better economic benefits. However, it is also extremely unstable. In addition, instability can easily occur under dynamic loads, such as earthquake action and pulsating wind effects. Therefore, it is necessary to study their mechanical behavior. Based on the horizontal swivel system of an 11,000-ton asymmetric continuous girder bridge, the dynamic response of the horizontal swivel system to seismic action was studied using the finite element simulation analysis method. Furthermore, using the Peer database, seismic waves that meet the calculation requirements are screened for time-history analysis and compared to the response spectrum method. The mechanical properties of the structural system during and after rotation were obtained through calculations. During rotation, the seismic response of the structure is greater. To reduce the calculation time cost, an optimization algorithm based on the mode shape superposition method is proposed. The calculation result is 87% that of the time-history analysis, indicating a relatively high calculation accuracy

An Improvement of Global Error Bound for the Generalized Nonlinear Complementarity Problem over a Polyhedral Cone

We consider the global error bound for the generalized nonlinear complementarity problem over a polyhedral cone (GNCP). By a new technique, we establish an easier computed global error bound for the GNCP under weaker conditions, which improves the result obtained by for GNCP

Theabrownin ameliorates liver inflammation, oxidative stress, and fibrosis in MCD diet-fed C57BL/6J mice

IntroductionNonalcoholic steatohepatitis (NASH), also known as metabolic steatohepatitis, is a clinical syndrome with pathological changes like alcoholic hepatitis but without a history of excessive alcohol consumption. NASH is closely related to metabolic disorders such as obesity, insulin resistance, type 2 diabetes mellitus, and hyperlipidemia. Its main characteristics are hepatocyte steatosis with hepatocyte injury and inflammation. In severe cases, it can develop into liver cirrhosis. At present, there is no special treatment for NASH. Theabrownin (TB) is the main pigment substance in fermented tea. Theabrownin has beneficial effects on lipid metabolism and intestinal flora. However, the effect of theabrownin on NASH has not been studied. MethodsThis study was aimed at exploring the effects of theabrownin from Fuzhuan brick tea on NASH. 8-week-old mice were randomly assigned to three groups and fed with chow diet (CD), methionine and choline sufficient (MCS) diet (MCS Ctrl), which is a Methionine/choline deficient (MCD) control diet, and MCD diet. After 5 weeks of feeding, the MCD group mice were randomly divided into two groups and were gavaged with double distilled water (MCD Ctrl) or theabrownin (MCD TB) (200mg/kg body weight, dissolved in double distilled water) every day for another 4 weeks respectively, while continuing MCD diet feeding.ResultsWe found that theabrownin treatment could not improve liver mass loss and steatosis. However, theabrownin ameliorated liver injury and decreased liver inflammatory response. Theabrownin also alleviated liver oxidative stress and fibrosis. Furthermore, our results showed that theabrownin increased hepatic level of fibroblast growth factor 21 (FGF21) and reduced the phosphorylation of mitogen-activated protein kinase p38 in MCD diet-fed mice