3 research outputs found
Photoredox-Induced Functionalization of Alkenes for the Synthesis of Substituted Imidazolines and Oxazolidines
A one-pot, three-component
cascade reaction combining photoredox
catalyzed radical addition and formal [3 + 2] annulation was developed.
With this approach, highly concise syntheses of imidazoline and oxazolidine
derivatives have been achieved. The advantages of this transformation
are good to excellent yields, mild reaction conditions, operational
simplicity, and easy accessibility of raw materials
Photoredox-Induced Functionalization of Alkenes for the Synthesis of Substituted Imidazolines and Oxazolidines
A one-pot, three-component
cascade reaction combining photoredox
catalyzed radical addition and formal [3 + 2] annulation was developed.
With this approach, highly concise syntheses of imidazoline and oxazolidine
derivatives have been achieved. The advantages of this transformation
are good to excellent yields, mild reaction conditions, operational
simplicity, and easy accessibility of raw materials
Regiospecific Three-Component Aminofluorination of Olefins via Photoredox Catalysis
Direct
visible-light-mediated aminofluorination of styrenes has
been developed with high regioselectivity. Shelf-stable <i>N</i>-Ts-protected 1-aminopyridine salt was used as the nitrogen-radical
precursor, and the commercially available hydrogen fluoride-pyridine
was used as the nucleophilic fluoride source. The synthesis of an
analogue of <b>LY503430</b> was performed to demonstrate the
synthetic value of this strategy