32 research outputs found

    The 100 most-cited articles in castration-resistant prostate cancer: a bibliometric analysis

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    Purpose: To assess the present landscape and future research directions, a bibliometric analysis was performed to identify the characteristics of the 100 most-cited articles (T100 articles) on CRPC research. Methods: A list of the T100 articles investigating CRPC was generated by searching the Web of Science (WoS) Core Collection database. Different characteristics of the T100 articles, including the countries/territories, journals, authors, and research areas, were analyzed. Results: The number of citations of T100 articles published between 1992 and 2017 ranged from 282 to 3594, with an average of 654.9 citations. According to the topic of the article, “Mechanisms related to tumor progression or metastasis” ranked first with 41 T100 articles, while immunotherapy ranked fourth with 7 T100 articles. The T100 articles originated from 31 countries, with more than half originating from the USA (n = 89). Professor Scher HI published the most T100 articles as the first author (4) and as the corresponding author (5), while Pro De Bono JS from the Institute of Cancer Research published 3 articles as the first author and 8 articles as the corresponding author. The journal Cancer Research published 20 T100 articles with a total of 8946 citations. The number of T100 articles (r = 0.485, P = 0.01) and the total number of citations (r = 0.626, P < 0.001) were all positively correlated with the IF of the journal. Conclusions: This analysis offers a historical perspective on the progress and attempts to reveal future trends in CRPC research using bibliometric analysis. This study’s results suggest that immunotherapy and the study of androgen receptors as well as their signaling axes will possibly be hot topics and trends in CRPC research

    Hybridization modeling of oligonucleotide SNP arrays for accurate DNA copy number estimation

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    Affymetrix SNP arrays have been widely used for single-nucleotide polymorphism (SNP) genotype calling and DNA copy number variation inference. Although numerous methods have achieved high accuracy in these fields, most studies have paid little attention to the modeling of hybridization of probes to off-target allele sequences, which can affect the accuracy greatly. In this study, we address this issue and demonstrate that hybridization with mismatch nucleotides (HWMMN) occurs in all SNP probe-sets and has a critical effect on the estimation of allelic concentrations (ACs). We study sequence binding through binding free energy and then binding affinity, and develop a probe intensity composite representation (PICR) model. The PICR model allows the estimation of ACs at a given SNP through statistical regression. Furthermore, we demonstrate with cell-line data of known true copy numbers that the PICR model can achieve reasonable accuracy in copy number estimation at a single SNP locus, by using the ratio of the estimated AC of each sample to that of the reference sample, and can reveal subtle genotype structure of SNPs at abnormal loci. We also demonstrate with HapMap data that the PICR model yields accurate SNP genotype calls consistently across samples, laboratories and even across array platforms

    Energy Storage Ceramics: A Bibliometric Review of Literature

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    Energy storage ceramics is among the most discussed topics in the field of energy research. A bibliometric analysis was carried out to evaluate energy storage ceramic publications between 2000 and 2020, based on the Web of Science (WOS) databases. This paper presents a detailed overview of energy storage ceramics research from aspects of document types, paper citations, h-indices, publish time, publications, institutions, countries/regions, research areas, highly cited papers, and keywords. A total of 3177 publications were identified after retrieval in WOS. The results show that China takes the leading position in this research field, followed by the USA and India. Xi An Jiao Tong Univ has the most publications, with the highest h-index. J.W. Zhai is the most productive author in energy storage ceramics research. Ceramics International, Journal of Materials Science-Materials in Electronics, and the Journal of Alloys and Compounds are the most productive journals in this field, and materials science—multidisciplinary is the most frequently used subject category. Keywords, highly cited papers, and the analysis of popular papers indicate that, in recent years, lead-free ceramics are prevalent, and researchers focus on fields such as the microstructure, thin films, and phase transition of ceramics

    Supply Chain Management: A Review and Bibliometric Analysis

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    Supply chain management (SCM), which generally refers to horizontal integration management, has steadily become the core competitiveness of company rivalry and an essential approach to developing national comprehensive and national strength since the end of the 20th century due to the numerous needs arising from a competitive international economy. Manufacturers develop a community of interest by forming long-term strategic partnerships with suppliers and vendors throughout the supply chain. This paper defines supply chain management by reviewing the existing literature and discusses the current state of supply chain management research, as well as prospective research directions. Specifically, we conducted a bibliometric analysis of the influential studies of SCM in terms of various aspects, such as research areas, journals, countries/regions, institutions, authors and corresponding authors, most cited publications, and author keywords, based on the 8998 reviews and articles collected from the SCI and SSCI database of the Web of Science (WoS) between 2010 and 2020. The results show that the major research areas were Management (3071, 34.13%), Operations Research &amp; Management Science (2680, 29.78%), and Engineering, Industrial (1854, 20.60%) with TP and TPR%. The most productive journal and institution were J. Clean Prod and Hong Kong Polytech Univ with a TP of 554 and 238, respectively. China, USA, and UK were the top three contributing countries. Furthermore, “sustainability”, “green supply chain (management)”, and “sustainable supply chain (management)” were the most popular author keywords in recent three years and since 2010, apart from the author keywords of SCM. When combined with the most cited articles in recent years, the application of block chain and Industry 4.0 in supply chain management increased rapidly and generated great attention

    Alternative Governance and Corporate Financial Fraud in Transition Economies: Evidence From China

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    How corporate governance mechanisms function in transition economies is a key topic for corporate governance researchers and policy makers. We propose that alternative governance mechanisms are in place to mitigate corporate fraudulent behaviors in the fluid state of transition economies where the establishment and enforcement of corporate governance legislation are presently insufficient. Drawing on the twin set of institutional logics—the institutional embeddedness logic and the institutional substitution logic—we posit that three salient types of prevailing alternative governance mechanisms (relational, administrative, and foreign governance) play important roles in transition economies because they are complementary to the institutional conditions at the time of the transition process. Conducting a bivariate probit analysis of a matched sample of corporate financial fraud cases in China, we find that strategic alliances, business group affiliation, nontradable state shares, local government ownership, use of foreign auditors, and foreign listing can deter corporate financial fraud, while foreign listing is also effective in detecting fraud. We also find that the deterrence effects of strategic alliances and business group affiliation become weaker as law development improves, while foreign listing and legal governance are completely substitutive. Our study provides a contextualized view of corporate governance that connects its effectiveness with institutionalization and the institutional state of a country. Our study also enriches our understanding of some unfamiliar forms of governance mechanisms that are in place and complementary to a country’s institutional conditions. </jats:p

    The deterrence effects of vicarious punishments on corporate financial fraud

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    This study extends the research on corporate financial fraud by developing a new perspective on the deterrence effects of vicarious punishments premised on social learning theory. We posit that firms vicariously learn about punishments from their peers by picking up modeling cues, environmental cues, and social cues in the inhibitive learning process, thus being deterred from committing future fraudulence. Using a matched sample of 604 observations of Chinese listed firms between 2002 and 2008, our findings show that an observing firm is deterred from committing fraud if the peers in its industry are caught and punished. We further find that such deterrence effects are subject to how the observing firm evaluates the possibility of being caught and the likelihood it will be punished the same way if it violates similar prohibitions. In particular, inhibitive learning effects are positively moderated by punishments of prominent firms and model–observer similarity but negatively attenuated by the development of the legal system. Our study sheds light on the corporate fraud literature by illuminating the indirect, inhibitive learning process from vicarious punishments and identifying the conditions for differential learning/deterrence outcomes of the observing firms. </jats:p

    Intimate Partner Violence: A Bibliometric Review of Literature

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    Intimate partner violence (IPV) is a worldwide public health problem. Here, a bibliometric analysis is performed to evaluate the publications in the Intimate Partner Violence (IPV) field from 2000 to 2019 based on the Science Citation Index (SCI) Expanded and the Social Sciences Citation Index (SSCI) databases. This work presents a detailed overview of IPV from aspects of types of articles, citations, h-indices, languages, years, journals, institutions, countries, and author keywords. The results show that the USA takes the leading position in this research field, followed by Canada and the U.K. The University of North Carolina has the most publications and Harvard University has the first place in terms of h-index. The London School of Hygiene and Tropical Medicine leads the list of average citations per paper. The Journal of Interpersonal Violence, Journal of Family Violence and Violence Against Women are the top three most productive journals in this field, and Psychology is the most frequently used subject category. Keywords analysis indicates that, in recent years, most research focuses on the research fields of &ldquo;child abuse&rdquo;, &ldquo;pregnancy&rdquo;, &ldquo;HIV&rdquo;, &ldquo;dating violence&rdquo;, &ldquo;gender-based violence&rdquo; and &ldquo;adolescents&rdquo;

    Bibliometric analysis of the 100 top-cited articles on immunotherapy of urological cancer

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    Purpose To highlight the scientific progress in immunotherapy of urological cancer by identifying and analyzing the 100 top-cited (T100) articles from the last 15 years. Methods Papers in immunotherapy of urological cancer were identified from Clarivate Web of Science Core Collection database. Data of the T100 articles and papers published in recent 2 years, including citations, topic, year of publication, country of origin, institution and authorship, were extracted and analyzed. Results Of the T100 articles, the citation number ranged from 7387 to 183 with a mean of 590.66. The USA led the field with 80 T100 articles and 53097 citations. Pro Sharma P from MD Anderson Cancer Center was at the top of list with 8 T100 articles (3 as first author and 6 as corresponding author). Memorial Sloan Kettering Cancer Center ranked first with 26 T100 articles and 22573 citations, followed by Johns Hopkins University with 21 T100 articles and 25095 citations. Forty-nine T100 articles were related to the renal cancer, followed by prostate cancer (29), bladder cancer (13) and urothelial cancer (13). According to the type of immunotherapy, most T100 articles were related to ICI (55 articles) and vaccine (19 articles). Conclusions It is the first bibliometric analysis to identify the T100 articles on immunotherapy of urological cancer. The USA made great contribution in the field of immunotherapy related to urological cancer. Renal, bladder and prostate cancers were the major organs treated by immunotherapy especially by ICIs and vaccines. The multiple aspects of ICIs research in renal and bladder cancer and the neoantigen-based vaccine therapy will be hotspots for future research

    Fund manager skill in an era of globalization: Offshore concentration and fund performance

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    We study how mutual fund managers gain an edge in selecting stocks in an era of globalization. We use textual analysis to construct a measure that captures a mutual fund\u27s offshore exposure concentration through holding US multinational firms. We find that funds with a higher offshore concentration index (OCI) perform significantly better, with the difference in four-factor alpha between the top and bottom deciles amounting to 2.95% per annum. Fund managers’ overweighting of firms with operations in certain countries can be partly attributed to their foreign ethnicity. High OCI fund managers have an information advantage regarding firms’ fundamentals, such as earnings
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