Comparison of the Adequacy Index and Log Likelihood ratios of diagnostic models.

<p>Comparison of the Adequacy Index and Log Likelihood ratios of diagnostic models.</p

Comparison of serum MCP-1, prolactin and AFP levels in HCC and non-HCC patients.

<p>Serum concentrations of (A) MCP-1, (B) prolactin and (C) AFP in non-HCC chronic hepatitis B carriers (NC group, n = 115) and HCC patients (HCC group, n = 126) in the SGH cohort of patients were analyzed by multiplex sandwich ELISA (Quantibody Array). Serum MCP-1 concentrations in asymptomatic HBV/HCV carriers (AC group, n = 100), chronic hepatitis patients with evidence of transaminitis (CH group, n = 101) and HCC patients (HCC group, n = 98) in the MRIN cohort (A) were analyzed by sandwich ELISA. The boxes represent the central 50% of the data, spanning between the 25^th and 75^th percentiles and the horizontal line within each box indicates the median. The cut-off points were: 1.5×IQR above 75^th percentile (upper limit) and 1.5×IQR below 25^th percentile (lower limit). Values beyond the cut-off points were considered as outliers and are represented by the dots. Comparison of biomarker values between groups was performed using the Mann-Whitney <i>U</i> test.</p

Demographics of patients (SGH cohort).

<p>Demographics of patients (SGH cohort).</p

Correlation between serum markers estimated by Spearman’s rank correlation coefficient, rho (n = 241).

*<p>The upper part are the Spearman’s rank correlation coefficients, rho; the lower part are the p-values of the Spearman’s rank correlation test.</p