The roof of the left orbit of SK196 showing signs of cribra orbitalia.

<p>Photo: Åge Hojem, NTNU Vitenskapsmuseet.</p

The skull of SK259 showing the trepanation hole in the posterior part of the right parietal bone.

<p>Photo: Åge Hojem, NTNU Vitenskapsmuseet.</p

Left lateral view of the radiographed cranium of SK196 showing the characteristic “hair on end” pattern seen in porotic hyperostosis.

<p>Left lateral view of the radiographed cranium of SK196 showing the characteristic “hair on end” pattern seen in porotic hyperostosis.</p

The right parietal of SK196 displaying signs of pitting indicative of porotic hyperostosis.

<p>Photo: Åge Hojem, NTNU Vitenskapsmuseet.</p

The right tibia and fibula of SK259 showing periostitis on the central and distal parts of the diaphysis of both bones.

<p>Similar lesions are also found on the left tibia and fibula. Photo: Åge Hojem, NTNU Vitenskapsmuseet.</p

Map of Colombia showing the geographic distribution of the major linguistic groups at the time of the Spanish colonization (a) and in the present day (b), the major entrance routes in Colombia during the peopling of South America (dashed arrows in a) and the location of the population groups analysed in this study (c).

<p>Data used to produce this figure are included in references [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0120155#pone.0120155.ref005" target="_blank">5</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0120155#pone.0120155.ref009" target="_blank">9</a>].</p

Effect of COMT-polymorphism and 5-HTTLPR on the Context Redundancy (CR) of the MTP.

<p>Effect of COMT-polymorphism and 5-HTTLPR on the Context Redundancy (CR) of the MTP.</p

Phylogenetic network of the Native American mtDNA (a) and Y chromosome (b) haplotypes detected in this study.

<p>Circle size is proportional to the number of haplotypes and branch size is proportional to the number of polymorphisms that distinguish each pair of haplotypes. Dashed lines delimit different haplogroups.</p

Effect of COMT-polymorphism and 5-HTTLPR on the Symbol Redundancy (SR) of the MTP.

<p>Effect of COMT-polymorphism and 5-HTTLPR on the Symbol Redundancy (SR) of the MTP.</p

Distribution of COMT and 5-HTTLPR genotypes.

<p>Distribution of COMT and 5-HTTLPR genotypes.</p