62 research outputs found
Machine Learning for Long-Distance Quantum Communication
Machine learning can help us in solving problems in the context of big-data analysis and classification, as well as in playing complex games such as Go. But can it also be used to find novel protocols and algorithms for applications such as large-scale quantum communication? Here we show that machine learning can be used to identify central quantum protocols, including teleportation, entanglement purification, and the quantum repeater. These schemes are of importance in long-distance quantum communication, and their discovery has shaped the field of quantum information processing. However, the usefulness of learning agents goes beyond the mere reproduction of known protocols; the same approach allows one to find improved solutions to long-distance communication problems, in particular when dealing with asymmetric situations where the channel noise and segment distance are nonuniform. Our findings are based on the use of projective simulation, a model of a learning agent that combines reinforcement learning and decision making in a physically motivated framework. The learning agent is provided with a universal gate set, and the desired task is specified via a reward scheme. From a technical perspective, the learning agent has to deal with stochastic environments and reactions. We utilize an idea reminiscent of hierarchical skill acquisition, where solutions to subproblems are learned and reused in the overall scheme. This is of particular importance in the development of long-distance communication schemes, and opens the way to using machine learning in the design and implementation of quantum networks
The SZT2 Interactome Unravels New Functions of the KICSTOR Complex
Seizure threshold 2 (SZT2) is a component of the KICSTOR complex which, under catabolic conditions, functions as a negative regulator in the amino acid-sensing branch of mTORC1. Mutations in this gene cause a severe neurodevelopmental and epileptic encephalopathy whose main symptoms include epilepsy, intellectual disability, and macrocephaly. As SZT2 remains one of the least characterized regulators of mTORC1, in this work we performed a systematic interactome analysis under catabolic and anabolic conditions. Besides numerous mTORC1 and AMPK signaling components, we identified clusters of proteins related to autophagy, ciliogenesis regulation, neurogenesis, and neurodegenerative processes. Moreover, analysis of SZT2 ablated cells revealed increased mTORC1 signaling activation that could be reversed by Rapamycin or Torin treatments. Strikingly, SZT2 KO cells also exhibited higher levels of autophagic components, independent of the physiological conditions tested. These results are consistent with our interactome data, in which we detected an enriched pool of selective autophagy receptors/regulators. Moreover, preliminary analyses indicated that SZT2 alters ciliogenesis. Overall, the data presented form the basis to comprehensively investigate the physiological functions of SZT2 that could explain major molecular events in the pathophysiology of developmental and epileptic encephalopathy in patients with SZT2 mutations
Measurement-based quantum communication with resource states generated by entanglement purification
institute for biomedical engineering
Model-based segmentation techniques for fast volume conductor generatio
Percutaneous radiofrequency ablation (RFA) of hepatic metastases in patients with metastatic breast cancer: An interim analysis
Transformation of o-toluate in Pseudomonas putida isolate 1065 and Rhizopus japonicus ATCC 24794
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