19,443 research outputs found
Machine Science in Biomedicine: Practicalities, Pitfalls and Potential
Machine Science, or Data-driven Research, is a new and interesting scientific
methodology that uses advanced computational techniques to identify, retrieve,
classify and analyse data in order to generate hypotheses and develop models.
In this paper we describe three recent biomedical Machine Science studies, and
use these to assess the current state of the art with specific emphasis on data
mining, data assessment, costs, limitations, skills and tool support
Observation of Single Transits in Supercooled Monatomic Liquids
A transit is the motion of a system from one many-particle potential energy
valley to another. We report the observation of transits in molecular dynamics
(MD) calculations of supercooled liquid argon and sodium. Each transit is a
correlated simultaneous shift in the equilibrium positions of a small local
group of particles, as revealed in the fluctuating graphs of the particle
coordinates versus time. This is the first reported direct observation of
transit motion in a monatomic liquid in thermal equilibrium. We found transits
involving 2 to 11 particles, having mean shift in equilibrium position on the
order of 0.4 R_1 in argon and 0.25 R_1 in sodium, where R_1 is the nearest
neighbor distance. The time it takes for a transit to occur is approximately
one mean vibrational period, confirming that transits are fast.Comment: 19 pages, 8 figure
Optimizing multi-dimensional terahertz imaging analysis for colon cancer diagnosis
Peer reviewedPublisher PD
Hypercalcemic Nephropathy in the Dog
Calcium is a functionally important ion and coenzyme in most all of the body systems. Besides its structural role in bone, calcium is involved in muscle contraction, the blood coagulation system, enzyme activity, nerve impulse transmission, hormone release and membrane permeability.I-3 Calcium metabolism is regulated primarily by parathyroid hormone (PTH), calcitonin (CT), and vitamin D (1,25-dihydroxycholecalciferol). The release of these hormones is controlled by the concentration of calcium in the plasma. Exact regulation of calcium in extracellular fluid is necessary to maintain normal body function
Scaling Analysis and Evolution Equation of the North Atlantic Oscillation Index Fluctuations
The North Atlantic Oscillation (NAO) monthly index is studied from 1825 till
2002 in order to identify the scaling ranges of its fluctuations upon different
delay times and to find out whether or not it can be regarded as a Markov
process. A Hurst rescaled range analysis and a detrended fluctuation analysis
both indicate the existence of weakly persistent long range time correlations
for the whole scaling range and time span hereby studied. Such correlations are
similar to Brownian fluctuations. The Fokker-Planck equation is derived and
Kramers-Moyal coefficients estimated from the data. They are interpreted in
terms of a drift and a diffusion coefficient as in fluid mechanics. All partial
distribution functions of the NAO monthly index fluctuations have a form close
to a Gaussian, for all time lags, in agreement with the findings of the scaling
analyses. This indicates the lack of predictive power of the present NAO
monthly index. Yet there are some deviations for large (and thus rare) events.
Whence suggestions for other measurements are made if some improved
predictability of the weather/climate in the North Atlantic is of interest. The
subsequent Langevin equation of the NAO signal fluctuations is explicitly
written in terms of the diffusion and drift parameters, and a characteristic
time scale for these is given in appendix.Comment: 6 figures, 54 refs., 16 pages; submitted to Int. J. Mod. Phys. C:
Comput. Phy
Adiabatic and Non-Adiabatic Contributions to the Free Energy from the Electron-Phonon Interaction for Na, K, Al, and Pb
We calculate the adiabatic contributions to the free energy due to the
electron--phonon interaction at intermediate temperatures, for the elemental metals Na, K, Al, and Pb. Using our
previously published results for the nonadiabatic contributions we show that
the adiabatic contribution, which is proportional to at low
temperatures and goes as at high temperatures, dominates the
nonadiabatic contribution for temperatures above a cross--over temperature,
, which is between 0.5 and 0.8 , where is the melting
temperature of the metal. The nonadiabatic contribution falls as for
temperatures roughly above the average phonon frequency.Comment: Updated versio
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