Boiling the Frog Slowly:The Immersion of C-Suite Financial Executives into Fraud

This study explores how financial executives retrospectively account for their crossing the line into financial statement fraud while acting within or reacting to a financialized corporate environment. We conduct our investigation through face-to-face interviews with 13 former C-suite financial executives who were involved in and indicted for major cases of accounting fraud. Five different themes of accounts emerged from the narratives, characterizing executives' fraud immersion as a meaning-making process by which the particulars of the proximal social context (the influence of social actors and contextual characteristics) and individual motivations collectively molded executives' vocabularies of fraud immersion. Our executives' narratives portray their fraud entanglement as typically occurring in small, incremental steps. Their accounts expand our understanding of the influence of socialization on executive-level financial fraud beyond the individualized focus of the fraud triangle model

Biotechnology for the Environment

Joint US-European Community Pilot Program support for short-term exchanges of early career scientists

The HST Survey of BL Lacertae Objects. I. Surface Brightness Profiles, Magnitudes, and Radii of Host Galaxies

We report on a large HST imaging survey of BL Lac objects, at spatial resolution ~10 times better than previous ground-based surveys. We focus on data reduction and analysis, describing the procedures used to model the host galaxy surface brightness radial profiles. A total of 69 host galaxies were resolved out of 110 objects observed, including almost all sources at z < 0.5. We classify them morphologically by fitting with either an exponential disk or a de~Vaucouleurs profile; when one fit is preferred over the other, in 58 of 69 cases, it is invariably the elliptical morphology. This is a very strong result given the large number of BL Lac objects, the unprecedented spatial resolution, and the homogeneity of the data set. With the present reclassification of the host galaxy of 1418+546 as an elliptical, there remain no undisputed examples of a disk galaxy hosting a BL Lac nucleus. This implies that, at 99% confidence, fewer than 7% of BL Lacs can be in disk galaxies. The apparent magnitude of the host galaxies varies with distance as expected if the absolute magnitudes are approximately the same, with a spread of +-1 mag, out to redshift z < 0.5. At larger redshifts, only 6 of 23 BL Lacs are resolved so the present data do not constrain possible luminosity evolution of the host galaxies. The collective Hubble diagram for BL Lac host galaxies and radio galaxies strongly supports their unification.Comment: Accepted for publication on ApJS. 43 pages. 10 figures. Figure 1 can also be downloaded from http://icarus.stsci.edu/~scarpa/tmp/hst_figure1.ta

The HST Survey of BL Lacertae Objects. II. Host Galaxies

We have used the HST WFPC2 camera to survey 132 BL Lac objects comprising seven complete radio-, X-ray-, and optically-selected samples. We obtained useful images for 110 targets spanning the redshift range 0 < z < 1.3. In two thirds of the BL Lac images, host galaxies are detected, including nearly all for z < 0.5 (58 of 63). The highest redshift host galaxy detected is in a BL Lac object at z=0.664. In 58 of the 72 resolved host galaxies, a de Vaucouleurs profile is significantly preferred, at >99% confidence, over a pure exponential disk; the two fits are comparable in the remaining 14 cases. These results limit the number of disk systems to at most 8% of BL Lacs (at 99% confidence), and are consistent with all BL~Lac host galaxies being ellipticals. The detected host galaxies are luminous ellipticals with a median absolute K-corrected magnitude of M_R= -23.7 +- 0.6 mag, at least one magnitude brighter than M* and comparable to brightest cluster galaxies. The galaxy morphologies are generally smooth and undisturbed, with small or negligible ellipticities (<0.2). There is no correlation between host galaxy and observed nuclear magnitude or estimated jet power corrected for beaming. If black hole mass is correlated linearly with bulge mass in general, this implies a large range in Eddington ratio. Present data strongly support the unification picture with FR I galaxies constituting the bulk of the parent population of BL Lac objects.Comment: Accepted for publication on ApJ. 38 pages, 8 figure

Mixtures of wild-type and a pathogenic (E22G) form of Abeta40 in vitro accumulate protofibrils, including amyloid pores

Although APP mutations associated with inherited forms of Alzheimer's disease (AD) are relatively rare, detailed studies of these mutations may prove critical for gaining important insights into the mechanism(s) and etiology of AD. Here, we present a detailed biophysical characterization of the structural properties of protofibrils formed by the Arctic variant (E22G) of amyloid-beta protein (Abeta40(ARC)) as well as the effect of Abeta40(WT) on the distribution of the protofibrillar species formed by Abeta40(ARC) by characterizing biologically relevant mixtures of both proteins that may mimic the situation in the heterozygous patients. These studies revealed that the Arctic mutation accelerates both Abeta oligomerization and fibrillogenesis in vitro. In addition, Abeta40(ARC) was observed to affect both the morphology and the size distribution of Abeta protofibrils. Electron microscopy examination of the protofibrils formed by Abeta40(ARC) revealed several morphologies, including: (1) relatively compact spherical particles roughly 4-5 nm in diameter; (2) annular pore-like protofibrils; (3) large spherical particles 18-25 nm in diameter; and (4) short filaments with chain-like morphology. Conversion of Abeta40(ARC) protofibrils to fibrils occurred more rapidly than protofibrils formed in mixed solutions of Abeta40(WT)/Abeta40(ARC), suggesting that co-incubation of Abeta40(ARC) with Abeta40(WT) leads to kinetic stabilization of Abeta40(ARC) protofibrils. An increase in the ratio of Abeta(WT)/Abeta(MUT(Arctic)), therefore, may result in the accumulation of potential neurotoxic protofibrils and acceleration of disease progression in familial Alzheimer's disease mutation carriers