Passively cooled glass CO2 laser tubes for severe environments

The objective of this effort was to design a glass CO2 laser tube that could survive the Titan 3 C launch environment and at the same time provide adequate thermal conductivity to maintain the wall of the laser tube below approximately equal to 50 C for efficient lasing. The approach that was taken to satisfy these requirements was to pot the tube in an aluminum heat sink using a space qualified polyurethane potting material. Two configurations of the laser tube successfully passed the complete Titan 3 C qualification level sine and random vibration specification and satisfied the thermal requirements. Fabrication details and test results are presented that indicate this could be a practical solution for laser tubes used in a severe environment and where flowing coolants are impractical or undesirable

Profile of allergy-related articles in the primary academic publication for UK General Practitioners

Background: Concern is often expressed about primary health care professionals’ lack of knowledge about allergies, particularly diagnostic testing and the management of atopic disorders. Limited training opportunities in allergy have been documented in both undergraduate and postgraduate education. The British Journal of General Practice is the leading UK-based Family Practice journal, it has a strong clinical focus. The BJGP was established in 1953. It is a high quality journal and is the world’s 2nd most highly cited journal of general practice and primary care. Methods: Keyword search of bjgp.org. Terms used were ‘allergy’, ‘allergies’, ‘allergic’, ‘rhinitis’, ‘urticaria’, ‘eczema’, ‘angioedema’. All titles and articles from 1953 to 2013 were searched. Full copies of relevant publications were downloaded and variables extracted, including title, year of publication, type of article, clinical focus. As a comparator a similar search was conducted for articles about asthma using the search term ‘asthma’. Results: 41 allergy-related articles were identified in the 60 years since the journal was launched. In the same time period there were 147 articles about asthma. In 31 of the 60 years reviewed there were no articles at all about any allergy-related topic. The focus of the articles published were eczema (6), food allergy (6), rhinoconjunctivitis (5), anaphylaxis (4), urticaria (1). There were no articles on angioedema. Some articles addressed multiple atopic disorders, eg ‘Allergic diseases in the elderly’ (1968), ‘Allergic disorders amongst horticultural, agricultural and forestry workers’ [letter] (1965). Conclusions: Allergy has a low profile in the British Journal of General Practice. This low profile persists despite the increasing prevalence of atopic disorders and major national reports highlighting the need for better care of the allergic patient in primary care. Our exploratory study highlights a missed opportunity to educate and inform General Practitioners about allergy through this widely circulated journal. Further work is needed to understand better why so few articles on allergy are published in the BJGP. If the paucity of publications reflects the number of articles submitted then BSACI members interested in informing and improving allergy management in General Practice should include the BJGP on their list of target journals. Where next: To share these observations with the Editor of the BJGP to understand whether they reflect editorial policy or lack of submissions from clinicians and researchers with expertise in allergy. To work with the BJGP to identify collaborative initiatives to address the serious mismatch between the prevalence of allergy in the clinical consultation and the number of allergy- related articles in the literature for GPs

Biaxial constitutive equation development

In developing the constitutive equations an interdisciplinary approach is being pursued. Specifically, both metallurgical and continuum mechanics considerations are recognized in the formulation. Experiments will be utilized to both explore general qualitative features of the material behavior that needs to be modeled and to provide a means of assessing the validity of the equations being developed. The model under development explicitly recognizes crystallographic slip on the individual slip systems. This makes possible direct representation of specific slip system phenomena. The present constitutive formulation takes the anisotropic creep theory and incorporates two state variables into the model to account for the effect of prior inelastic deformation history on the current rate-dependent response of the material

Radiation damage in GaAs solar cells

Recent results of electron and proton irradiation and annealing of GaAs solar cells are presented along with some implications of these results. A comparison between the energy-levels produced by protons and by electrons which are not stopped in the material indicate that the damage produced by protons and electrons may be qualitatively different. Thus, annealing of proton damage may be very different from the annealing of electron damage

Method of reducing temperature in high-speed photography

A continuing problem in high-speed motion picture photography is adequate lighting and the associated temperature rise. Large temperature rises can damage subject matter and make recording of the desired images impossible. The problem is more severe in macrophotography because of bellows extension and the necessary increase in light. This report covers one approach to reducing the initial temperature rise: the use of filters and heat-absorbing materials. The accompanying figures provide the starting point for selecting distance as a function of light intensity and determining the associated temperature rise. Using these figures will allow the photographer greater freedom in meeting different photographic situations

Constitutive modelling of single crystal and directionally solidified superalloys

The trend towards improved engine efficiency and durability places increasing demands on materials that operate in the hot section of the gas turbine engine. These demands are being met by new coatings and materials such as single crystal and directionally solidified nickel-base superalloys which have greater creep/fatigue resistance at elevated temperatures and reduced susceptibility to grain boundary creep, corrosion and oxidation than conventionally cast alloys. Work carried out as part of a research program aimed at the development of constitutive equations to describe the elevated temperature stress-strain-time behavior of single crystal and directionally solidified turbine blade superalloys is discussed. The program involves both development of suitable constitutive models and their verification through elevated temperature tension-torsion testing of single crystals of PWA 1480

Nonlinear mechanics of composite materials with periodic microstructure

This report summarizes the result of research done under NASA NAG3-882 Nonlinear Mechanics of Composites with Periodic Microstructure. The effort involved the development of non-finite element methods to calculate local stresses around fibers in composite materials. The theory was developed and some promising numerical results were obtained. It is expected that when this approach is fully developed, it will provide an important tool for calculating local stresses and averaged constitutive behavior in composites. NASA currently has a major contractual effort (NAS3-24691) to bring the approach developed under this grant to application readiness. The report has three sections. One, the general theory that appeared as a NASA TM, a second section that gives greater details about the theory connecting Greens functions and Fourier series approaches, and a final section shows numerical results

Constitutive Modeling of Superalloy Single Crystals and Directionally Solidified Materials

A unified viscoplastic constitutive relation based on crystallographic slip theory was developed for the deformation analysis of nickel base face centered cubic superalloy single crystals at elevated temperature. The single crystal theory is embedded in a self consistent method to derive a constitutive relation for a directionally solidified material comprised of a polycrystalline aggregate of columnar cylindrical grains. One of the crystallographic axes of the cylindrical crystals points in the columnar direction while the remaining crystallographic axes are oriented at random in the basal plane perpendicular to the columnar direction. These constitutive formulations are coded in FORTRAN for use in nonlinear finite element and boundary element programs

Applicability of the control configured design approach to advanced earth orbital transportation systems

The applicability of the control configured design approach (CCV) to advanced earth orbital transportation systems was studied. The baseline system investigated was fully reusable vertical take-off/horizontal landing single-stage-to-orbit vehicle and had mission requirements similar to the space shuttle orbiter. Technical analyses were made to determine aerodynamic, flight control and subsystem design characteristics. Figures of merit were assessed on vehicle dry weight and orbital payload. The results indicated that the major parameters for CCV designs are hypersonic trim, aft center of gravity, and control surface heating. Optimized CCV designs can be controllable and provide substantial payload gains over conventional non-CCV design vertical take-off vehicles

Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone

We have applied the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens to a cell-free system for the regeneration of the nicotinamide cofactors NAD and NADP in the biological production of the important semisynthetic opiate drug hydromorphone. The original recombinant whole-cell system suffered from cofactor depletion resulting from the action of an NADP(+)-dependent morphine dehydrogenase and an NADH-dependent morphinone reductase. By applying a soluble pyridine nucleotide transhydrogenase, which can transfer reducing equivalents between NAD and NADP, we demonstrate with a cell-free system that efficient cofactor cycling in the presence of catalytic amounts of cofactors occurs, resulting in high yields of hydromorphone. The ratio of morphine dehydrogenase, morphinone reductase, and soluble pyridine nucleotide transhydrogenase is critical for diminishing the production of the unwanted by-product dihydromorphine and for optimum hydromorphone yields. Application of the soluble pyridine nucleotide transhydrogenase to the whole-cell system resulted in an improved biocatalyst with an extended lifetime. These results demonstrate the usefulness of the soluble pyridine nucleotide transhydrogenase and its wider application as a tool in metabolic engineering and biocatalysis