Odds ratios of soy product intake and isoflavone intake for development of ulcerative colitis.

<p>OR, odds ratio; CI, confidence interval.</p><p>^*Tertiles were based on intake in g/4184 kJ or mg/4184 kJ adjusted for energy intake using the density method.</p>†<p>Adjusted for age, gender, body mass index, history of appendicitis, family history of ulcerative colitis, smoking and alcohol drinking status.</p><p>Odds ratios of soy product intake and isoflavone intake for development of ulcerative colitis.</p

Characteristics of the 126 cases and 170 controls.

<p>SD, standard deviation.</p><p>^*Data expressed as n (%) unless otherwise indicated.</p>†<p>The χ² test or Wilcoxon rank-sum test were employed where appropriate.</p>§<p>Nutrient intake was adjusted for total energy intake using the density method.</p><p>Characteristics of the 126 cases and 170 controls.</p

Additional file 1: of Identification of predictive markers of the therapeutic effect of eribulin chemotherapy for locally advanced or metastatic breast cancer

Univariate and multivariate analysis with respect to progression free survival in 52 locally advanced or metastatic breast cancer. In a multivariate analysis including TLE3 and Ki67, no biomarkers useful for predicting the efficacy of eribulin in cases of MBC were found. (DOCX 16 kb

The association between consumption of selected beverages and ALT reduction of 20 IU/L or more during 12 months of follow-up among patients with higher ALT level at baseline (N=147).

<p>Model includes: sex, age (≤61, 62-69, 70+ years), body mass index (≤20, 21-23, 24+ kg/m²), smoking status (never/former, current), alcohol drinking status (never/former, current), diabetes mellitus, platelet count (<10 ×10⁴/μL ) and other beverages in table except decaffeinated coffee.</p

Baseline characteristics of study subjects according to filtered coffee consumption.

<p><i>P</i> values of characteristics between categories of filtered coffee consumption were calculated by analysis of chi-square test or Fisher's exact test and Kruskal-Wallis test.</p><p>SD, standard deviation; ALT, alanine aminotransferase; BMI, body mass index</p><p>^* 182 patients among the normal ALT group and 107 patients among the higher ALT group were analyzed; the duration of HCV infection could not be calculated in 87 patients due to lack of information.</p

Baseline characteristics of the study subjects and beverages consumption according to baseline ALT levels.

<p><i>P</i> values of characteristics and beverages consumption between categories of baseline ALT levels were calculated by analysis of chi-square test or Fisher's exact test and Kruskal-Wallis test.</p><p>SD, standard deviation; ALT, alanine aminotransferase; BMI, body mass index</p><p>^* 182 patients among the normal ALT group and 107 patients among the higher ALT group were analyzed; the duration of HCV infection could not be calculated in 87 patients due to lack of information.</p

The association between consumption of selected beverages and normal ALT level (≤45 IU/L) during 12 months of follow-up among patients with normal ALT level at baseline (N=229).

<p>Model includes: sex, age (≤61, 62-70, 71+ years), body mass index (≤20, 21-23.4, 23.5+ kg/m2), smoking status (never/former, current), alcohol drinking status (never/former, current), diabetes mellitus, platelet count (<10 ×104/μL) and other beverages in the table.</p

Table_1_Shunt Intervention for Possible Idiopathic Normal Pressure Hydrocephalus Improves Patient Outcomes: A Nationwide Hospital-Based Survey in Japan.DOCX

<p>Background and Purpose: This study aimed to investigate the efficacy of cerebrospinal fluid shunt intervention for idiopathic normal pressure hydrocephalus (iNPH) using data from a nationwide epidemiological survey in Japan.</p><p>Methods: We conducted a cross-sectional study using data from a nationwide epidemiological survey performed in Japan. Propensity score matching was used to select 874 patients from 1,423 patients aged ≥60 years, who were diagnosed with iNPH based on clinical guidelines following a hospital visit in 2012. Patients who experienced an improvement of at least 1 modified Rankin Scale (mRS) grade after the intervention were classified as “improved,” while the remaining patients were classified as “non-improved.” In the shunt intervention (n = 437) and non-shunt intervention (n = 437) groups, the differences in mRS grade improvement were analyzed using the Mann-Whitney U-test. Finally, we examined subjects in the shunt intervention group (n = 974) to compare the outcomes and complications of ventriculoperitoneal (VP) shunt (n = 417) with lumboperitoneal (LP) shunt (n = 540).</p><p>Results: We examined subjects with iNPH to compare the non-shunt intervention group to the shunt intervention group following adjustment for age and mRS grade at baseline by propensity score matching (0.31–0.901). The mRS grade (mean [SD]) was found to improve with non-shunt intervention (2.46 [0.88]) and shunt intervention (1.93 [0.93]) (p < 0.001) in iNPH patients. The mRS outcome score and complications comparison between the VP and LP shunt groups did not show significant difference.</p><p>Conclusions: In this study, analysis of the efficacy of shunts for possible iNPH conducted in Japan indicated a significant improvement in the mRS grade between baseline and outcome within 1 year, regardless of the surgical technique, and shunt intervention was found to be effective.</p