The Evolution of Ireland's Kerry Group/PLC-Implications for the U.S. and Global Dairy-Food Industries

This Discussion Paper is a case study of Kerry Group/PLC of Ireland. Kerry grew from a small dairy cooperative (annual sales of US $50 million) in the early 1970s into an international food ingredients and consumer food products company with sales of US$2.6 billion in 1998. Kerry Group/PLC provides a model that US and other dairy-food firms interested in exporting dairy-based food ingredients or engaging in foreign direct investment in food ingredients businesses might emulate.Kerry Group/PLC of Ireland, Irish Dairy Industry, Agribusiness, Farm Management, Industrial Organization, International Development,

When Will U.S. Firms Become Major Dairy Exporters and Bigger Direct Investors in Foreign Dairy-Food Businesses?

The prospects for substantially expanded dairy exports by U.S. firms are not bright for at least the current decade. The exceptions relate to exports of dried whey, whey fractions, dairy blends, selected specialty dairy products and nonfat dry milk. U.S. dairy exports are likely to continue to be low because U.S. prices for bulk dairy products are sharply higher than world prices. Unlike the situation for dairy exporting, the barriers to foreign direct investment by U.S. firms appear less daunting. The prevalence of successful foreign direct investments by the foreign firms described here suggests that a larger number of U.S. firms could engage in such investments successfully.U.S. Dairy Exports, Foreign Direct Investment, U.S. Dairy Firms, Demand and Price Analysis, Industrial Organization, International Relations/Trade,

Therapeutic/Expressive Writing and Resilience Promotion for Nurses to Reduce Burnout Syndrome

COVID-19 accelerated the rate in which nurses were unable to maintain resilience and reduce burnout. This evidence-based DNP project obtained data from a therapeutic/expressive writing intervention and group resilience discussion with Women’s Care Center (WCC) nurses to improve resilience acuity and reduce symptoms associated with burnout syndrome. A review of previous studies indicated therapeutic/expressive writing and group resilience discussions have been beneficial in improving resilience and reducing burnout. A demographic and two preintervention surveys were completed by WCC nurses in the hospital relaxation room or skills lab. The Connor-Davidson RISC-25© was used to determine resilience scores for morning and evening shift nurses. The Maslach Burnout Inventory© (MBI) Survey for Medical Personnel was used to assess emotional exhaustion (EE), depersonalization (DP), and personal achievement (PA) in the same groups. Participants (n =20) nurses completed the pre-intervention resilience and burnout surveys. Day and night shift nurses (n= 19) resilience mean average increased after the intervention 2.65 mean score (M = 83.31, SD =9.86) for the Connor-Davidson RISC-25© survey which is in the intermediate range: 50% of the population. The burnout mean for the morning shift nurses, EE (M = 21.88), DP (M = 4.88), and PA (M = 39.27) which indicated moderate burnout for all categories. The burnout means for evening shift nurses, EE (M = 17.33), DP (M = 7.22), and PA (M = 40.00), which fell within the moderate burnout range

Multichannel error correction code decoder

A brief overview of a processing satellite for a mesh very-small-aperture (VSAT) communications network is provided. The multichannel error correction code (ECC) decoder system, the uplink signal generation and link simulation equipment, and the time-shared decoder are described. The testing is discussed. Applications of the time-shared decoder are recommended

Multiple strand displacement amplification of mitochondrial DNA from clinical samples

<p>Abstract</p> <p>Background</p> <p>Whole genome amplification (WGA) methods allow diagnostic laboratories to overcome the common problem of insufficient DNA in patient specimens. Further, body fluid samples useful for cancer early detection are often difficult to amplify with traditional PCR methods. In this first application of WGA on the entire human mitochondrial genome, we compared the accuracy of mitochondrial DNA (mtDNA) sequence analysis after WGA to that performed without genome amplification. We applied the method to a small group of cancer cases and controls and demonstrated that WGA is capable of increasing the yield of starting DNA material with identical genetic sequence.</p> <p>Methods</p> <p>DNA was isolated from clinical samples and sent to NIST. Samples were amplified by PCR and those with no visible amplification were re-amplified using the Multiple Displacement Amplificaiton technique of whole genome amplification. All samples were analyzed by mitochip for mitochondrial DNA sequence to compare sequence concordance of the WGA samples with respect to native DNA. Real-Time PCR analysis was conducted to determine the level of WGA amplification for both nuclear and mtDNA.</p> <p>Results</p> <p>In total, 19 samples were compared and the concordance rate between WGA and native mtDNA sequences was 99.995%. All of the cancer associated mutations in the native mtDNA were detected in the WGA amplified material and heteroplasmies in the native mtDNA were detected with high fidelity in the WGA material. In addition to the native mtDNA sequence present in the sample, 13 new heteroplasmies were detected in the WGA material.</p> <p>Conclusion</p> <p>Genetic screening of mtDNA amplified by WGA is applicable for the detection of cancer associated mutations. Our results show the feasibility of this method for: 1) increasing the amount of DNA available for analysis, 2) recovering the identical mtDNA sequence, 3) accurately detecting mtDNA point mutations associated with cancer.</p

Arterial heparan sulfate is negatively associated with hyperglycemia and atherosclerosis in diabetic monkeys

BACKGROUND: Arterial proteoglycans are implicated in the pathogenesis of atherosclerosis by their ability to trap plasma lipoproteins in the arterial wall and by their influence on cellular migration, adhesion and proliferation. In addition, data have suggested an anti-atherogenic role for heparan sulfate proteoglycans and a pro-atherogenic role for dermatan sulfate proteoglycans. Using a non-human primate model for human diabetes, studies examined diabetes-induced changes in arterial proteoglycans that may increase susceptibility to atherosclerosis. METHODS: Control (n = 7) and streptozotocin-induced diabetic (n = 8) cynomolgous monkeys were assessed for hyperglycemia by measurement of plasma glycated hemoglobin (GHb). Thoracic aortas obtained at necropsy, were extracted with 4 M guanidine HCL and proteoglycans were measured as hexuronic acid. Atherosclerosis was measured by enzymatic analysis of extracted tissue cholesterol. Glycosaminoglycan chains of arterial proteoglycans were released with papain, separated by agarose electrophoresis and analysed by scanning densitometry. RESULTS: Tissue cholesterol was positively associated with hexuronic acid content in diabetic arteries (r = .82, p < .025) but not in control arteries. Glycosaminoglycan chain analysis demonstrated that dermatan sulfate was associated with increased tissue cholesterol in both control (r = .8, p < 0.05) and diabetic (r = .8, p < .025) arteries, whereas a negative relationship was observed between heparan sulfate and tissue cholesterol in diabetic arteries only (r = -.7, p < .05). GHb, which was significantly higher in diabetic animals (8.2 ± 0.9 vs 3.8 ± 0.2%, p < .0005) was negatively associated with heparan sulfate in diabetic arteries (r = -.7, p < .05). CONCLUSIONS: These data implicate hyperglycemia induced modifications in arterial proteoglycans that may promote atherosclerosis

The theophylline‐enoxacin interaction: I. Effect of enoxacin dose size on theophylline disposition

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110004/1/cptclpt1988197.pd