7,282 research outputs found

    Security, Privacy, and Technology Development: The Impact on National Security

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    The evolution of modern communications and information technology sparked a revolution of unprecedented proportions, bringing about an explosion in terms of users and capabilities, as well as increasing demands for both security and privacy. To meet these security demands, new technologies are evolving that can in fact provide a secure and protected environment. At the same time, however, the technology-development path is being increasingly impacted by two other major dynamics: the legal environment and user expectations with respect to privacy. Within the past four years in particular, several major court decisions as well as the official release of documents and illicit “leaks” have drawn enormous attention to what privacy protections must be afforded to various types of data and communications. Users, increasingly aware of intrusions into their data and communications—ranging from intelligence services to hackers and criminals—are demanding greater levels of protection. While technological approaches to greater privacy are possible, they are not costfree— particularly in terms of the computational overhead and other constraints imposed on new systems

    Security, Privacy, and Technology Development: The Impact on National Security

    Get PDF
    The evolution of modern communications and information technology sparked a revolution of unprecedented proportions, bringing about an explosion in terms of users and capabilities, as well as increasing demands for both security and privacy. To meet these security demands, new technologies are evolving that can in fact provide a secure and protected environment. At the same time, however, the technology-development path is being increasingly impacted by two other major dynamics: the legal environment and user expectations with respect to privacy. Within the past four years in particular, several major court decisions as well as the official release of documents and illicit “leaks” have drawn enormous attention to what privacy protections must be afforded to various types of data and communications. Users, increasingly aware of intrusions into their data and communications—ranging from intelligence services to hackers and criminals—are demanding greater levels of protection. While technological approaches to greater privacy are possible, they are not costfree— particularly in terms of the computational overhead and other constraints imposed on new systems

    Tubular Diseases and Stones Seen From Pediatric and Adult Nephrology Perspectives

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    The tubular system of the kidneys is a complex series of morphologic and functional units orchestrating the content of tubular fluid as it flows along the nephron and collecting ducts. Renal tubules maintain body water, regulate electrolytes and acid-base balance, reabsorb precious organic solutes, and eliminate specific metabolites, toxins, and drugs. In addition, decisive mechanisms to adjust blood pressure are governed by the renal tubules. Genetic as well as acquired disorders of these tubular functions may cause serious diseases that manifest both in childhood and adulthood. This article addresses a selection of tubulopathies and the underlying pathomechanisms, while highlighting the important differences in pediatric and adult nephrology care. These range from rare monogenic conditions such as nephrogenic diabetes insipidus, cystinosis, and Bartter syndrome that present in childhood, to the genetic and acquired tubular pathologies causing hypertension or nephrolithiasis that are more prevalent in adults. Both pediatric and adult nephrologists must be aware of these conditions and the age-dependent manifestations that warrant close interaction between the two subspecialties

    Nova Sagittarii 1994 #1 (V4332 Sagittarii): The Discovery and Evolution of an Unusual Luminous Red Variable Star

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    We report photometry and spectroscopy of the evolution of Nova Sagittarii 1994 #1 (V4332 Sagittarii) during outburst. We compare the photometric and spectral evolution of this outburst to known classes of outbursts -- including classical novae and outbursts occurring on symbiotic stars -- and find this object does NOT conform to any known class of outburst. The closest match to the behavior of this unusual object is M31 RV, an extremely luminous and red variable object discovered in the bulge of M31 in 1988. However, the temporal behavior and maximum luminosity of the two events differ by several orders of magnitude, requiring substantial intrinsic variation if these two events are members the same type of outburst. Our model of the spectroscopic evolution of this outburst shows that the effective temperature cooled from 4400 K to 2300 K over the three month span of our observations. In combination with line diagnostics in our later spectra, including [OI] lambda 5577 and the dramatic increase in the Halpha to Hbeta ratio, we infer the existence of a cool, dense (N_e ~ 10^{8-9} cm^{-3}) envelope that is optically thick in the Hydrogen Balmer recombination lines (case C). We suggest that a nuclear event in a single star, in which a slow shock drove the photosphere outwards, can power the observed luminosity evolution and the emission spectrum.Comment: Accepted for publication in AJ. 24 pages including 8 embedded postscript figures. Also available at http://www.astronomy.ohio-state.edu/~martini/pub

    Fv antibodies to aflatoxin B1 derived from a pre-immunized antibody phage display library system

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    The production and characterization of recombinant antibodies to aflatoxin B[SUB1] (AFB[SUB1]), a potent mycotoxin and carcinogen is described. The antibody fragments produced were then applied for use in a surface plasmon resonance-based biosensor (BIAcore), which measures biomolecular interactions in 'real-time'. Single chain Fv (scFv) antibodies were generated to aflatoxin B1 from an established phage display system, which incorporated a range of different plasmids for efficient scFv expression. The scFv's were used in the development of a competitive ELISA, and also for the development of surface plasmon resonance (SPR)-based inhibition immunoassays. They were found to be suitable for the detection of AFB[SUB1], in this format, with the assays being sensitive and reproducible

    Ornstein-Uhlenbeck parameter extraction from light curves of Fermi-LAT observed blazars

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    Context. Monthly-binned gamma-ray light curves of 236 bright gamma-ray sources, particularly blazars, selected from a sample of 2278 high-galactic latitude objects observed with Fermi-LAT, show flux variability characterized by power spectral densities consisting of a single power-law component, ranging from Brownian to white noise. Aims. The main goal here is to assess the Ornstein-Uhlenbeck (OU) model by studying the range of its three parameters that reproduces these statistical properties. Methods. We develop procedures for extracting values of the three OU model parameters (mean flux, correlation length, and random amplitude) from time series data, and apply them to compare numerical integrations of the OU process with the Fermi-LAT data. Results. The OU process fully describes the statistical properties of the flux variations of the 236 blazars. The distributions of the extracted OU parameters are narrowly peaked about well-defined values (sigma, mu, theta) = (0.2, -8.4, 0.5) with variances (0.004, 0.07, 0.13). The distributions of rise and decay time scales of flares in the numerical simulations, i.e. major flux variations fulfilling pre-defined criteria, are in agreement with the observed ones. The power spectral densities of the synthetic light curves are statistically indistinguishable from those of the measured light curves. Conclusions. Long-term gamma-ray flux variability of blazars on monthly time scales is well described by a stochastic model involving only three parameters. The methods described here are powerful tools to study randomness in light curves and thereby constrain the physical mechanisms responsible for the observed flux variations.Comment: 13 pages, 9 figure

    Ursinus College Alumni Journal, July 1953

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    President\u27s page • 135 degrees awarded at 83rd annual commencement • Rev. J. Alfred Kaye commencement speaker • Baccalaureate sermon delivered by Rev. Shaffer • Medical students accomplishment report • Dr. Lauer and Rev. Jeffers elected to Board of Directors • Sun Oil president speaks to business admin. students • Ursinus summer sessions open June 4 and July 23 • Dr. Johnson honored by Western Reserve • Open scholarships awarded to seven high school seniors • Sun shines on delightful Ursinus May Day • Five local alumni groups hold spring meetings • President Glassmoyer talks things over • Alumni president Kermit Black ill • Rain fails to dampen friendly spirit of Alumni Day • Portrait of Dr. Brownback presented to Ursinus • Montgomery County homes opened for women\u27s tour • Provident Mutual wants Ursinus grads • Marion Sis Bosler coaches Ursinus mermaids • Baseball squad has best record in 39 years • Dawkins takes a first in Middle Atlantics • Track resume for 1953 • Captain Kenney only veteran tennis player • Women\u27s softball team closes another undefeated season • Women\u27s tennis team wins five, loses four • News about ourselves • Necrology • John Manning honored in mathematical competition • Alumni association plans permanent class organizationhttps://digitalcommons.ursinus.edu/alumnijournal/1046/thumbnail.jp
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