Laparoscopic splenectomy for a large multilocular splenic cyst with elevated CA19-9: Report of a case

AbstractINTRODUCTIONBecause splenic cysts are rare, a definitive treatment regime for these cysts remains unclear. We report a case of a large multilocular splenic cyst with elevated carbohydrate antigen 19-9 (CA19-9) levels, which was successfully treated with laparoscopic splenectomy.PRESENTATION OF CASEA 22-year-old female was admitted to our hospital with severe left upper abdominal pain. Serum CA19-9 level was mildly elevated (65U/ml). Computed tomography revealed a 25-cm long spleen with multilocular cystic lesions, for which an emergency laparoscopic splenectomy was performed. Histological findings revealed that the lesion was a benign true cyst, and immunostaining analyses showed that the epithelium was CA19-9-positive.DISCUSSIONAlthough some spleen-preserving approaches have been reportedly used, splenic cyst recurrence usually occurs in true cyst cases, wherein the cyst is incompletely removed. Most reported cases of splenic cysts producing CA19-9 are true cysts.CONCLUSIONThe treatment approach should be decided on the basis of the type, shape, location, and even CA19-9 levels of the splenic cyst

CHOP欠損はマウスにおける肝虚血再灌流障害を軽減する

京都大学0048新制・課程博士博士(医学)甲第21415号医博第4405号京都大学大学院医学研究科医学専攻(主査)教授 妹尾 浩, 教授 坂井 義治, 教授 川口 義弥学位規則第4条第1項該当Doctor of Medical ScienceKyoto UniversityDFA