6 research outputs found
Exosomes Released from Mycoplasma Infected Tumor Cells Activate Inhibitory B Cells
- Author
- A Blanchard
- A Clayton
- A Clayton
- A Herbelin
- A Rieger
- B Zhang
- BC Cole
- BF Flanagan
- BJ Quah
- C Brenner
- C Liu
- C Schmidhauser
- C Thery
- C Thery
- C Thery
- Chenjie Yang
- CS Zurita-Salinas
- DA Kostyal
- DA Kostyal
- DD Taylor
- DD Taylor
- G Rawadi
- Geetha Chalasani
- GH Cassell
- GR Paton
- I Macpherson
- J Garcia
- J Wolfers
- K Denzer
- K Namiki
- K Pietsch
- K Sugimura
- LM Bergquist
- M Gong
- M Tarshis
- N Burdin
- Niels Olsen Saraiva Câmara
- Paul D. Robbins
- PJ Chan
- R Madan
- R Valenti
- RH Bennett
- S Bhatnagar
- S Bhatnagar
- S Huang
- S Razin
- S Rottem
- S Tsai
- S Yu
- S Zhang
- SH Feng
- SH Kim
- SH Kim
- WL Beatty
- Yue-Harn Ng
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
Mycoplasmas cause numerous human diseases and are common opportunistic pathogens in cancer patients and immunocompromised individuals. Mycoplasma infection elicits various host immune responses. Here we demonstrate that mycoplasma-infected tumor cells release exosomes (myco+ exosomes) that specifically activate splenic B cells and induce splenocytes cytokine production. Induction of cytokines, including the proinflammatory IFN-γ and the anti-inflammatory IL-10, was largely dependent on the presence of B cells. B cells were the major IL-10 producers. In splenocytes from B cell deficient μMT mice, induction of IFN-γ+ T cells by myco+ exosomes was greatly increased compared with wild type splenocytes. In addition, anti-CD3-stimulated T cell proliferation was greatly inhibited in the presence of myco+ exosome-treated B cells. Also, anti-CD3-stimulated T cell signaling was impaired by myco+ exosome treatment. Proteomic analysis identified mycoplasma proteins in exosomes that potentially contribute to the effects. Our results demonstrate that mycoplasma-infected tumor cells release exosomes carrying mycoplasma components that preferentially activate B cells, which in turn, are able to inhibit T cell activity. These results suggest that mycoplasmas infecting tumor cells can exploit the exosome pathway to disseminate their own components and modulate the activity of immune cells, in particular, activate B cells with inhibitory activity
Verifiable threshold quantum secret sharing with sequential communication
- Author
- A Shamir
- A Tavakoli
- Alexandra Boldyreva
- AM Lance
- C Asmuth
- C Schmidt
- CB Lu
- Changbin Lu
- CM Bai
- D Markham
- F Gao
- Fuyou Miao
- FY Miao
- GP Guo
- GP He
- H Lai
- H Lai
- H Lu
- H Qin
- HK Lau
- I Kogias
- IC Yu
- ID Ivanovic
- J Wang
- Junpeng Hou
- Keju Meng
- L Harn
- L Harn
- LY Hsu
- M Hillery
- R Cleve
- R Rahaman
- RJ McEliece
- V Karimipour
- W Tittel
- W Yang
- WL Wootters
- XL Song
- Y Tokunaga
- Y Wu
- YA Chen
- YG Desmedt
- YH Yang
- YN Liu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Photochemical Degradation of Dissolved Organic Carbon to Carbon Monoxide in Coastal Seawater
- Author
- AJ Gabric
- B Jhne
- DF Wilson
- DJ Erickson
- FJ Millero
- FJ Millero
- H Sakugawa
- J Harn
- JE Johnson
- JW Swinnerton
- JW Swinnerton
- JW Swinnerton
- JW Swinnerton
- K Bauer
- K Mopper
- K Ohta
- PE Wilkniss
- PS Liss
- PS Liss
- R Conrad
- R Conrad
- R Conrad
- R Conrad
- RA Lamontagne
- RD Jones
- RD Jones
- RD Jones
- RD Jones
- RL Valentine
- SM Table
- TS Bates
- VJ Linnenbom
- W Seiler
- W Seiler
- WL Miller
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2000
- Field of study
Isochaihulactone protects PC12 cell against H2O2 induced oxidative stress and exerts the potent anti-aging effects in D-galactose aging mouse model
- Author
- A Kumar
- AK Lee
- C Sridhar
- CA Sack
- Chai-ching Lin
- Ching-ju Lin
- DD Kitts
- De-chuan Chan
- F Fang
- Giou-teng Yiang
- H Wei
- HM Huang
- Horng-jyh Harn
- JH Liu
- KJ Barnham
- KJ Yun
- Kuo-jung Su
- L Feng
- L Li
- L Luckenbill-Edds
- LH Chen
- M He
- M Valko
- Min-hui Chien
- N Hamada
- P Tachon
- R Tome Ada
- RA Floyd
- RC Hou
- RG Jordens
- RL Willson
- S Yamauchi
- S Yamauchi
- Shih-bin Lin
- SR Adderley
- ST Yin
- Sung-liang Yu
- T Finkel
- T Nakamura
- Tzong-der Way
- WL Chang
- X Cui
- X Cui
- XH Xu
- XW Yang
- Yi-lin Sophia Chen
- YL Chen
- YL Chen
- YP Jang
- Yung-luen Yu
- YX Shen
- ZF Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Disequilibrium evolution of the Fructose-1,6-bisphosphatase gene family leads to their functional biodiversity in Gossypium species
- Author
- A Abdelraheem
- A Chueca
- A Strand
- AH Paterson
- AI Saeed
- AJ Serrato
- B Hu
- B Zhao
- BASRA A S M.C.P
- C Schnarrenberger
- CA Beasley
- CH Harn
- CN Hirsch
- D Lang
- D Wang
- E Khayat
- E Schaper
- F Li
- F Li
- G Zimmermann
- G. A. Tuskan
- GL Ouriel Faktor
- H Guo
- H Obiadalla-Ali
- H Xiao
- HC Park
- HJ Kim
- HK Jang
- J Bose
- J Cao
- J Chatterjee
- J Daie
- J Guo
- J Schmutz
- J Su
- J Zhang
- J Zhang
- JA Banks
- JA Rojas-Gonzalez
- JA Wang
- JD Thompson
- JE DeVay
- JF Suo
- JF WENDEL
- JF Wendel
- JF Wendel
- JJ Lee
- K Fan
- K Tamura
- K Wang
- KJ Livak
- L Fang
- L Wang
- L Xu
- LA Rogers
- Laurence D Hurst
- LE Anderson
- M Ashraf
- M Lescot
- M Luo
- M Wang
- MH Cho
- O Jaillon
- PJ Rushton
- PT Li
- Q Hu
- R Huckelhoven
- R Zrenner
- RD Finn
- RL Brown
- S Al-Robaiy
- S Ghosh
- S Liu
- S Ouyang
- SB Cannon
- SC Huber
- SK Lee
- T Zhang
- T Zhu
- W Fang
- W Sun
- W Xu
- WL Xu
- WT Nel
- X Argout
- X Du
- X Guan
- X Lan
- X Liu
- X Wang
- Xu
- Y Cai
- Y Hu
- Y Hur
- Y Li
- Y Wang
- Y Zhang
- Z Ma
- Z Sun
- Z Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Der Mineralstoffwechsel der Zelle
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- A Amann
- A Bolliger
- A Cali
- A Couceiro
- A Cretin
- A Djabri
- A Drilion
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- A ENGSTRÖM
- A ENGSTRÖM
- A Engström
- A ENGSTRÖM
- A Engström
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- A Fischer
- A Guardabassi
- A Guardabassi
- A Guardabassi
- A Hastings
- A Hess
- A Hirschman
- A Jorio
- A Kabat
- A Kabat
- A Kabat
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- A Kitiyakara
- A Krogh
- A Lacassagne
- A Lacassagne
- A Lacassagne
- A Lacassagne
- A Lacassagne
- A Leaf
- A Loveless
- A Marshak
- A Marshak
- A Marshak
- A Mcmillen
- A Morse
- A Phil
- A Policard
- A Policard
- A Policard
- A Policard
- A Schultz
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- A Soulairac
- A Soulairac
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- A Treadwell
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- AM Seligman
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- and T. GOODSPEED
- AP Winogradoff
- AusTONI M. E., and D. M. GREENBERG
- AXEL-ROD D. J., and J. G. HAMILTON Radioautographic studies of distribution of lewisite and mustard gas in skin and eye tissues. Amer
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- CHAIkOFF J. L.
- Changes in alkaline phosphatase activity of rat vaginal epithelium during the estrous cycle
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- Monnier A. M.
- MooG F.
- MP Hele
- MV Ardenne
- MW Burril
- N Andresen
- N Andresen
- N Tiel
- N Tupikowa
- NEEDHAM
- Neuxomm S.
- NG Chlopin
- NH Woodruf
- NI Berlin
- NI Berlin
- NM Sulkin
- NM Sulkin
- NO Kaplan
- NO Lindberg
- NovIKOFF A. B., V. R. POTTER and G. A. LE PAGE
- NovlxoFF A. B.
- NovnioFF A. B., E. PODBER and J. RYAN
- NOVrKOFF A. B., L. HECHT, E. PODBER and J. RYAN
- O Chiewitz
- O Lindahl
- O Pettengill
- O Shulman
- O Turpeinen
- OE Killer
- OE Kugler
- OH Lowry
- OH Lowry
- OP Jones
- ORENT-KEILES E., and E. V. McCoLLUM
- P Dangeard
- P Desaive
- P Desclaux
- P Ernst
- P Györgi
- P Klemperer
- P Makarow
- P Rieser
- P Wyckoff
- P. D. Altland
- PB Hudson
- PB Kutsky
- PB Pearson
- PB Weisz
- PDE Fonbrune
- PF Hahn
- PF Hahn
- PF Hahn
- PF Hahn
- PF Hahn
- PF Hahn
- PF Hahn
- PH Abelson
- PH Mitchell
- PJ Fitzgerald
- PJ Fitzgerald
- PK Stumpf
- PL Kirk
- PoBJAK G., and M.-L
- PorrCHARD J J • Alkaline phosphatase in the uterine epithelium of the rat
- PouLsoN D. F., and V. T. BOWEN
- PouLSON D. F., V. T. BOWEN, R. M. HILSE and A. C. RUBINSON
- PS Timiras
- PS Williams
- R Angeli
- R Cloetens
- R Courrier
- R Dubach
- R Gerschman
- R Grant
- R HÖBER
- R Jeener
- R Lindner
- R Maccardle
- R Nicolaysen
- R Richterich
- R Rugh
- R Schoenheimer
- R Silberberg
- R Silberberg
- R Wagner
- RA Dudley
- RA Huseby
- RA Kehoe
- RA Kritzler
- RA Mccance
- RA Peters
- RAR Gresson
- RC Goldberg
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RC Maccardle
- RD Lillie
- RD Lillie
- RE Goldsmith
- RE Stowell
- RF Sognaes
- RG Sinclair
- RHA Plimmer
- RHA Plimmer
- RJ Gautheret
- RJL Allen
- RL Huff
- RL Lierke
- RM Bethke
- RM Fink
- RM Hodges
- RMC Dawson
- RO Greet
- RO Stafford
- Robison R.
- RoNKIN R. R.
- RosE M. S., and H. J. HUBBEL
- RR Bensley
- RR Bensley
- RS Manly
- RT Stewart
- RW Manly
- RW Mowry
- S Albert
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Baginsky
- S Belfer
- S Brody
- S Edlbacher
- S Gage
- S Granick
- S Granick
- S Hertz
- S HÉBERT
- S Lagerstedt
- S Minamitami
- S Rapoport
- S Schujenioff
- S Sherlock
- SA Dangelo
- SA Komarov
- SC Brooks
- SC Brooks
- SC Brooks
- SC Rothmann
- SC Werner
- ScHMITT F. O.
- SCHULTZ-BRAUNS O.
- SIwE S. A.
- SJ Folley
- SL Baker
- SR Pelc
- SR Pelc
- SR Pelc
- SS Stahl
- ST Bayley
- T Addis
- T Astrup
- T Caspersson
- T Caspersson
- T Caspersson
- T Caspersson
- T Cornbleet
- T Gileman
- T Goodspeed
- T Kuttner
- T Teorell
- T Teorell
- T Yamamoto
- TC Evans
- TF Zucker
- TH Evans
- The turnover of phosphate in the pineal body compared with
- Theoretical and technical study of autography as a histological method for localization of radioactive elements
- THV Brandt
- TR Fukuda
- TTA Cloi
- U Borell
- U Trierfelder
- V Hamburger
- V Suntzeff
- VB Peters
- VE Cosslett
- VE Kinsey
- VE Kinsey
- VERNADSKY W. J.
- VERZAR and MACDOUGAL
- VILLEE C. A., M. LOWENS, M. GORDON, E. LEONARD and A. RICH
- VISSCHER M. B., R. R. ROEPKE and N. LIFSON
- VITAGLIANO G., and M. DE NICOLA
- VK Zworykin
- VL Koenig
- VM Emmel
- VOSBURGH J. GILBERT and L. B. FLEXNER
- VT Bowen
- W Bauer
- W Biedermann
- W Bladergroen
- W Bloom
- W Denis
- W Diemair
- W Fenn
- W Gerlach
- W Gerlach
- W Gerlach
- W Gerlach
- W Hanle
- W Heubner
- W Kutscher
- W Lintzel
- W Mann
- W Montagna
- W Newman
- W Newman
- W Trachler
- W Wilbrandt
- WA Rawlinson
- WB Atkinson
- WB Cannon
- WB Hawkins
- WB Hawkins
- WC Schneider
- WD Armstrong
- WD Armstrong
- WD Block
- WD Sullivan
- WE Corn
- WE Gaunt
- WE Siri
- WE Stone
- WF Neumann
- WF Neumann
- WF Windl
- WGE Ecgleton
- WI Morse
- Winter and Smith
- WJ Ellis
- WL Doyle
- WL Hard
- WL Hard
- WL Harn
- WL Percival
- WL Simpson
- WM Balfour
- WM Beeson
- WMB Atkinson
- WMM Hart
- WO Cruz
- WO Fenn
- WR Tweedy
- WR Tweedy
- WS Emmerich
- WS Graff
- WT Pommerenke
- WU Gardner
- WW Campbell
- WW Petrowa
- Wwston C.
- YoKOYAMA H. O., R. E. STOWELL and R. M. MATHEWS
- Z Menschix
- ZITTLE. CH. A. L. A. WELLS and W. G. BLATT
- ZT Wirtschafter
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1955
- Field of study