Identification of a mitotic recombination hotspot on chromosome III of the asexual fungus Aspergillus niger and its possible correlation elevated basal transcription

Genetic recombination is an important tool in strain breeding in many organisms. We studied the possibilities of mitotic recombination in strain breeding of the asexual fungus Aspergillus niger. By identifying genes that complemented mapped auxotrophic mutations, the physical map was compared to the genetic map of chromosome III using the genome sequence. In a program to construct a chromosome III-specific marker strain by selecting mitotic crossing-over in diploids, a mitotic recombination hotspot was identified. Analysis of the mitotic recombination hotspot revealed some physical features, elevated basal transcription and a possible correlation with purine stretches

International indexing as a means of portfolio diversification

Global investing offers investors a larger pool of investment opportunities and tremendous diversification. However, despite the increased integration of world economies, there are still important variations among overseas capital markets. Complexities of overseas investing can often ensnare even the best active asset managers. International indexing is an option to overcome the difficulties of global investing. This study considers international indexing as a means of portfolio diversification. Performances of 15 international indexes are evaluated using monthly return data from 1998 through 2002. Returns are measured against ISE-100 Index (Istanbul Stock Exchange-100 Index) returns. The results of the study suggest that international indexing does not offer superior returns compared to the ISE-100 index.