19 research outputs found
Gender-Related Differences in the Dysfunctional Resting Networks of Migraine Suffers
BACKGROUND: Migraine shows gender-specific incidence and has a higher prevalence in females. However, little is known about gender-related differences in dysfunctional brain organization, which may account for gender-specific vulnerability and characteristics of migraine. In this study, we considered gender-related differences in the topological property of resting functional networks. METHODOLOGY/PRINCIPAL FINDINGS: Data was obtained from 38 migraine patients (18 males and 20 females) and 38 healthy subjects (18 males and 20 females). We used the graph theory analysis, which becomes a powerful tool in investigating complex brain networks on a whole brain scale and could describe functional interactions between brain regions. Using this approach, we compared the brain functional networks between these two groups, and several network properties were investigated, such as small-worldness, network resilience, nodal centrality, and interregional connections. In our findings, these network characters were all disrupted in patients suffering from chronic migraine. More importantly, these functional damages in the migraine-affected brain had a skewed balance between males and females. In female patients, brain functional networks showed worse resilience, more regions exhibited decreased nodal centrality, and more functional connections revealed abnormalities than in male patients. CONCLUSIONS: These results indicated that migraine may have an additional influence on females and lead to more dysfunctional organization in their resting functional networks
Surgical site infections after distal radius fracture surgery: a nation-wide cohort study of 31,807 adult patients
Polycyclic aromatic hydrocarbon concentrations in urban soils representing different land use categories in Shanghai
Trace metals and PAHs in topsoils of the University campus in the megacity of São Paulo, Brazil
Occurrence, Sources, and Potential Toxicity of Polycyclic Aromatic Hydrocarbons in Surface Soils from the Yellow River Delta Natural Reserve, China
Development of biomarkers inAporrectodea caliginosa andLumbricus rubellus for detecting exposure to benzo[a]pyrene
Imaging Pain in Arthritis: Advances in Structural and Functional Neuroimaging
Arthritis is a heterogeneous disease characterized by joint stiffness, swelling, and pain. Although primarily considered a peripheral joint disease, the severity of pain reported by arthritis patients does not always reflect the extent of joint pathology detectable by conventional means. Using structural and functional brain imaging techniques, a growing number of evolving neuroimaging methods are providing insight into these observed discrepancies at different time-scales. Of these methods, functional magnetic resonance imaging is exploited for short-term evoked pain examination and treatment evaluation; 'resting-state' approaches provide insight into fluctuations in pain; perfusion imaging captures elements of on-going clinical pain; and morphological brain assessment provides evidence for long-term structural changes in the brain associated with chronic pain. Further insight into arthritic pain processing at the brain-systems level could in the future be provided by combined neuroimaging approaches, specifically investigating the interactions between functional and structural alterations