10 research outputs found
Effectiveness of a smartphone app on improving immunization of children in rural Sichuan Province, China: a cluster randomized controlled trial
Prevalence of Mobile Phones and Factors Influencing Usage by Caregivers of Young Children in Daily Life and for Health Care in Rural China: A Mixed Methods Study
A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia
Wnt-induced Vangl2 Phosphorylation Is Dose-Dependently Required for Planar Cell Polarity in Mammalian Development
The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target
Shaping the nervous system: role of the core planar cell polarity genes.
Planar cell polarity (PCP) is complementary to the intrinsic polarization of single cells and refers to the global coordination of cell behaviour in the plane of a tissue, and by extension to the signalling pathways that control it. PCP is most evident in cell sheets and research into PCP was for years confined to studies in Drosophila. However, PCP has more recently emerged as an important phenomenon in vertebrates where it regulates various developmental processes and is associated with multiple disorders. In particular, core PCP genes are crucial for the development and function of the nervous system. They are involved in neural tube closure, ependymal polarity, neuronal migration, dendritic growth and axon guidance