Radioimmunoassay for pancreatic glucagon based on specific derivatisation of the hormone

A specific glucagon antiserum was generated in rabbits using a derivatisation of the methionine residue in glucagon. A sensitive and specific assay for glucagon has been developed. Interference with the assay system by plasma factors was abolished by both extraction of plasma samples and the production of glucagon-free plasma for each individual. Chemicals/CAS: glucagon, 11140-85-5, 62340-29-8, 9007-92-5; Aprotinin, 9087-70-1; Arginine, 74-79-3; Glucagon, 9007-92-5; S-methylglucagon, 68600-12-

Do handcycling time-trial velocities achieved by para-cycling athletes vary across handcycling classes?

The classification system for handcycling groups athletes into five hierarchical classes, based on how much their impairment affects performance. Athletes in class H5, with the least impairments, compete in a kneeling position, while athletes in classes H1 to H4 compete in a recumbent position. This study investigated the average time-trial velocity of athletes in different classes. A total of 1,807 results from 353 athletes who competed at 20 international competitions (2014–2018) were analyzed. Multilevel regression was performed to analyze differences in average velocities between adjacent pairs of classes, while correcting for gender, age, and event distance. The average velocity of adjacent classes was significantly different (p <.01), with higher classes being faster, except for H4 and H5. However, the effect size of the differences between H3 and H4 was smaller (d = 0.12). Hence, results indicated a need for research in evaluating and developing evidence-based classification in handcycling, yielding a class structure with meaningful performance differences between adjacent classes

Do Handcycling Time-Trial Velocities Achieved by Para-Cycling Athletes Vary Across Handcycling Classes?

The classification system for handcycling groups athletes into five hierarchical classes, based on how much their impairment affects performance. Athletes in class H5, with the least impairments, compete in a kneeling position, while athletes in classes H1 to H4 compete in a recumbent position. This study investigated the average time-trial velocity of athletes in different classes. A total of 1,807 results from 353 athletes who competed at 20 international competitions (2014-2018) were analyzed. Multilevel regression was performed to analyze differences in average velocities between adjacent pairs of classes, while correcting for gender, age, and event distance. The average velocity of adjacent classes was significantly different (p < .01), with higher classes being faster, except for H4 and H5. However, the effect size of the differences between H3 and H4 was smaller (d = 0.12). Hence, results indicated a need for research in evaluating and developing evidence-based classification in handcycling, yielding a class structure with meaningful performance differences between adjacent classes

Valuing self-protection: income and certification effects for safe rooms

Survey data from Tulsa, Oklahoma residents are used to examine individual valuations of safe rooms. The study utilises two measures of individual valuations, the maximum willingness to pay (WTP) and willingness to accept (WTA) for safe rooms. The primary research questions are concerned with whether the willingness to pay measure exhibits income effects and whether certification standards make the safe room investment more desirable. The main findings can be summarised as follows. The mean willingness to pay for a safe room was $2,500. The value of certification by a national organisation increased willingness to pay for the safe room by$600 on average. There is no direct income effect in that respondents' stated willingness to pay does not bear a statistically significant relationship to reported income. There is evidence of a secondary income effect in that willingness to pay elicited from attendees of a suburban parade of homes was $731 higher than attendees of an urban parade of homes. A mortgage payment-based WTA measure yields mean valuations of the safe room more than three times higher than the lump sum WTP valuation.Safe room, willingness to pay, willingness to accept, valuation, certification,