Should New Anti-Malarial Drugs be Subsidized?

We use analytical and numerical models to explain and quantify the welfare effects of subsidies for artemisinin combination treatments (ACTs), a valuable new class of antimalarial drugs. There are two (second-best) efficiency rationales for such subsidies: by expanding drug use, they reduce infection transmission from one individual to another, and they slow the evolution of drug resistance by deterring use of substitute monotherapy drugs for which resistance emerges more rapidly than for ACTs. Our analysis merges epidemiological models of malaria transmission among individuals and mosquitoes, evolution of drug resistance, and economic models of the demand for alternative drugs; parameter values for the simulations are representative of malaria prevalence in sub-Saharan Africa. We find that large subsidies for ACT are welfare improving across many plausible scenarios for malaria transmission, drug-demand elasticities, and evolution of drug resistance; the benefits of the policy are often several times larger than the costs.antimalarial drugs, resistance externality, transmission externality, subsidies, welfare effects

Birefringence upper limit analysis of low birefringence fibers employed in the Faraday effect current sensors

The theoretical model of the Faraday rotation in the low birefringence optical fiber is proposed to serve as a convenient tool for the determination of the birefringence upper limit allowed to retain current sensor sensitivity. The measurement technique offers a fast and efficient determination of the ultra-low linear birefringence when other techniques are not sensitive enough or they are difficult to implement. A temperature dependence of the Faraday rotation and its causes are investigated

Effect of initial correlations on short-time decoherence

We study the effect of initial correlations on the short-time decoherence of a particle linearly coupled to a bath of harmonic oscillators. We analytically evaluate the attenuation coefficient of a Schroedinger cat state both for a free and a harmonically bound particle, with and without initial thermal correlations between the particle and the bath. While short-time decoherence appears to be independent of the system in the absence of initial correlations, we find on the contrary that, for initial thermal correlations, decoherence becomes system dependent even for times much shorter than the characteristic time of the system. The temperature behavior of this system dependence is discussed.Comment: 7 pages, 1 figur

Strippable coal reserves of Illinois : part 6, LaSalle, Livingston, Grundy, Kankakee, Will, Putnam, and parts of Bureau and Marshall counties

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Description of late Pennsylvanian strata from deep diamond drill cores in the southern part of the Illinois Basin

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FCPA Enforcement Against U.S. and Non-U.S. Companies

This Article explores how U.S. authorities have enforced the FCPA against non-U.S. companies and tests the perception that the FCPA disproportionately impacts U.S. businesses. After briefly discussing the FCPA, its enforcement, and its reach, this Article examines corporate FCPA enforcement activity since the statute’s enactment in 1977. It finds that foreign firms have actually fared worse under the FCPA despite the fact that DOJ and the SEC have brought more enforcement actions against domestic companies in absolute terms. The average cost of resolving an FCPA enforcement action to non-U.S. corporations of resolving an FCPA enforcement action has been more than four times higher than it has been for domestic corporations: $72.3 million to$17.6 million. In recent years, the difference has been even more pronounced—in 2017, the averages were $150.3 million and$16.1 million, respectively. This Article also explores other ways in which FCPA enforcement has more dramatically affected foreign companies. For instance, U.S. enforcement authorities have more frequently required post-resolution obligations for foreign corporations. Between 2004 and 2018, nearly 60 percent of foreign companies involved in FCPA enforcement actions were subject to post-resolution obligations in the form of an independent compliance monitor, self-reporting, or a combination of the two, compared to only 54 percent of domestic companies. Finally, this Article offers some theories to explain these data