380 research outputs found
Aerodynamic and Radiative Controls on the Snow Surface Temperature
Abstract
The snow surface temperature (SST) is essential for estimating longwave radiation fluxes from snow. SST can be diagnosed using finescale multilayer snow physics models that track changes in snow properties and internal energy; however, these models are heavily parameterized, have high predictive uncertainty, and require continuous simulation to estimate prognostic state variables. Here, a relatively simple model to estimate SST that is not reliant on prognostic state variables is proposed. The model assumes that the snow surface is poorly connected thermally to the underlying snowpack and largely transparent for most of the shortwave radiation spectrum, such that a snow surface energy balance among only sensible heat, latent heat, longwave radiation, and near-infrared radiation is possible and is called the radiative psychrometric model (RPM). The RPM SST is sensitive to air temperature, humidity, ventilation, and longwave irradiance and is secondarily affected by absorption of near-infrared radiation at the snow surface that was higher where atmospheric deposition of particulates was more likely to be higher. The model was implemented with neutral stability, an implicit windless exchange coefficient, and constant shortwave absorption factors and aerodynamic roughness lengths. It was evaluated against radiative SST measurements from the Canadian Prairies and Rocky Mountains, French Alps, and Bolivian Andes. With optimized and global shortwave absorption and aerodynamic roughness length parameters, the model is shown to accurately predict SST under a wide range of conditions, providing superior predictions when compared to air temperature, dewpoint, or ice bulb calculation approaches.</jats:p
Minimum-mass optimisation for high-rate manufacture of damage tolerant and unbuckled composite components
A significant increase in the rate of composite manufacture is needed to meet demand for short-range commercial aircraft. The enabling automated manufacturing processes can, however, induce undesirable process features such as wrinkles. Additionally, the potential for Barely Visible Impact Damage has resulted in widespread use of overly-conservative strain allowables which has led to overweight aircraft structures. Two new constraints are presented which enable formability and damage tolerance to be incorporated into a two-stage minimum-mass optimisation framework for performance and manufacturability. An efficient, approximate method is presented for determining a conservative lower bound on the strain required to propagate a single, circular delamination, given a general through-thickness position and an upper bound on delamination size. A Compatibility Index is used to predict the propensity for wrinkles to occur during a forming manufacturing process. Optimised stacking sequences for two benchmark design problems; a flat plate and blade-stiffened panel, are obtained subject to minimum formability, damage tolerance and buckling constraints alongside common industry design rules. The damage tolerance and formability constraints are met for a diverse set of design requirements, without increasing mass or reducing buckling load, thereby demonstrating that components may be optimised for manufacture using high-rate processes without detriment to performance.</p
A plate model for compressive strength prediction of delaminated composites
Damage tolerance is of critical importance to laminated composite structures. In this paper, we present a new semi-analytical method for predicting the strain at which delamination propagation will initiate following sublaminate buckling. The method uses a numerical strip model to determine the thin-film buckling strain of an anisotropic sub-laminate created by delamination, before evaluating the strain energy release rate for delamination propagation. The formulation assumes that all energy is available for propagation in a peeling mode (Mode I); avoiding an approximate mixed-mode criterion. Results are compared with twelve experimentally obtained propagations strains, covering a variety of laminates each containing a circular PTFE delamination. Comparison shows agreement to within 12% for balanced sublaminate tests in which delamination propagation occurred before intra-ply cracking. The method can be used to significantly improve the damage tolerance of laminates, opening up new opportunities for structural efficiency using elastic tailoring, non-standard ply angles and material optimisation.</p
Local Evolutionary Debunking Arguments
Evolutionary debunking arguments in ethics aim to use facts about the evolutionary causes of ethical beliefs to undermine their justification. Global Evolutionary Debunking Arguments (GDAs) are arguments made in metaethics that aim to undermine the justification of all ethical beliefs. Local Evolutionary Debunking Arguments (LDAs) are arguments made in firstâorder normative ethics that aim to undermine the justification of only some of our ethical beliefs. Guy Kahane, Regina Rini, Folke Tersman, and Katia Vavova argue for skepticism about the possibility of LDAs. They argue that LDAs cannot be successful because they overâextend in a way that makes them selfâundermining and yield a form of moral skepticism. In this paper I argue that this skepticism about the possibility of LDAs is misplaced
A Comparison of Components of Written Expression Abilities in Learning Disabled and Non-Learning Disabled Students at Three Grade Levels
Although written language plays a critical role in academic success, little empirical evidence exists on the normal development of processes involved in producing written products. Even less is known about the writing performance of LD children. This study empirically compared the written products of LD and normal students at three grade levels on The Test of Written Language. Results showed that LD subjects scored significantly lower than normal subjects on most written expression abilities, especially in the mechanical tasks of spelling, punctuation, and word usage.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
A plate model for compressive strength prediction of delaminated composites
Damage tolerance is of critical importance to laminated composite structures. In this paper, we present a new semi-analytical method for predicting the strain at which delamination propagation will initiate following sublaminate buckling. The method uses a numerical strip model to determine the thin-film buckling strain of an anisotropic sub-laminate created by delamination, before evaluating the strain energy release rate for delamination propagation. The formulation assumes that all energy is available for propagation in a peeling mode (Mode I); avoiding an approximate mixed-mode criterion. Results are compared with twelve experimentally obtained propagations strains, covering a variety of laminates each containing a circular PTFE delamination. Comparison shows agreement to within 12% for balanced sublaminate tests in which delamination propagation occurred before intra-ply cracking. The method can be used to significantly improve the damage tolerance of laminates, opening up new opportunities for structural efficiency using elastic tailoring, non-standard ply angles and material optimisation.The authors gratefully acknowledge the support of the EPSRC (EP/N024354/1) funding for the ADAPT project. Richard Butler holds the Royal Academy of Engineering â GKN Aerospace Research Chair in Composites Analysis
Upper Mantle Seismic Anisotropy Beneath the West Antarctic Rift System and Surrounding Region from Shear Wave Splitting Analysis
We constrain azimuthal anisotropy in the West Antarctic upper mantle using shear wave splitting parameters obtained from teleseismic SKS, SKKS and PKS phases recorded at 37 broad-band seismometres deployed by the POLENET/ANET project. We use an eigenvalue technique to linearize the rotated and shifted shear wave horizontal particle motions and determine the fast direction and delay time for each arrival. High-quality measurements are stacked to determine the best fitting splitting parameters for each station. Overall, fast anisotropic directions are oriented at large angles to the direction of Antarctic absolute plate motion in both hotspot and no-net-rotation frameworks, showing that the anisotropy does not result from shear due to plate motion over the mantle. Further, the West Antarctic directions are substantially different from those of East Antarctica, indicating that anisotropy across the continent reflects multiple mantle regimes. We suggest that the observed anisotropy along the central Transantarctic Mountains (TAM) and adjacent West Antarctic Rift System (WARS), one of the largest zones of extended continental crust on Earth, results from asthenospheric mantle strain associated with the final pulse of western WARS extension in the late Miocene. Strong and consistent anisotropy throughout the WARS indicate fast axes subparallel to the inferred extension direction, a result unlike reports from the East African rift system and rifts within the Basin and Range, which show much greater variation. We contend that ductile shearing rather than magmatic intrusion may have been the controlling mechanism for accumulation and retention of such coherent, widespread anisotropic fabric. Splitting beneath the Marie Byrd Land Dome (MBL) is weaker than that observed elsewhere within the WARS, but shows a consistent fast direction, possibly representative of anisotropy that has been âfrozen-inâ to remnant thicker lithosphere. Fast directions observed inland from the Amundsen Sea appear to be radial to the dome and may indicate radial horizontal mantle flow associated with an MBL plume head and low upper mantle velocities in this region, or alternatively to lithospheric features associated with the complex Cenozoic tectonics at the far-eastern end of the WARS
Upper Mantle Structure of Central and West Antarctica from Array Analysis of Rayleigh Wave Phase Velocities
The seismic velocity structure of Antarctica is important, both as a constraint on the tectonic history of the continent and for understanding solid Earth interactions with the ice sheet. We use Rayleigh wave array analysis methods applied to teleseismic data from recent temporary broadband seismograph deployments to image the upper mantle structure of central and West Antarctica. Phase velocity maps are determined using a twoâplane wave tomography method and are inverted for shear velocity using a Monte Carlo approach to estimate three-dimensional velocity structure. Results illuminate the structural dichotomy between the East Antarctic Craton and West Antarctica, with West Antarctica showing thinner crust and slower upper mantle velocity. West Antarctica is characterized by a 70â100âkm thick lithosphere, underlain by a low-velocity zone to depths of at least 200âkm. The slowest anomalies are beneath Ross Island and the Marie Byrd Land dome and are interpreted as upper mantle thermal anomalies possibly due to mantle plumes. The central Transantarctic Mountains are marked by an uppermost mantle slow-velocity anomaly, suggesting that the topography is thermally supported. The presence of thin, higher-velocity lithosphere to depths of about 70âkm beneath the West Antarctic Rift System limits estimates of the regionally averaged heat flow to less than 90âmW/m2. The Ellsworth-Whitmore block is underlain by mantle with velocities that are intermediate between those of the West Antarctic Rift System and the East Antarctic Craton. We interpret this province as Precambrian continental lithosphere that has been altered by Phanerozoic tectonic and magmatic activity
Groundwaterârock interactions in crystalline rocks: evidence from SIMS oxygen isotope data
The diffusive exchange of dissolved material between fluid flowing in a fracture and the enclosing wallrocks (rock matrix diffusion) has been proposed as a mechanism by which radionuclides derived from a radioactive waste repository may be removed from groundwater and incorporated into the geosphere. To test the effectiveness of diffusive exchange in igneous and metamorphic rocks, we have carried out an investigation of veins formed at low temperatures (<100°C), comparing the oxygen isotopic composition of vein calcite with that of secondary calcite in the wallrocks. Two examples of veins from the Borrowdale Volcanic Group, Cumbria, and one from the Mountsorrel Granodiorite, Leicestershire, UK, have remarkably similar vein calcite compositions, ca. +20â°(SMOW) or greater, substantially heavier than the probable compositions of the host rocks, and these vein calcite compositions are inferred to reflect the infiltrating fluid and the temperature of vein formation. Calcites from the wallrocks are similar to those in veins, with little evidence for exchange with the wallrocks. The results support existing models for this type of vein which suggest low-temperature growth from formation brines originally linked to Permian or Triassic evaporites. The results are consistent with flow through fractures being attenuated through a damage zone adjacent to the fracture and provide no evidence of diffusional exchange with pore waters from wallrocks
EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy
BACKGROUND: Diastolic dysfunction is central to diseases such as heart failure with preserved ejection fraction and hypertrophic cardiomyopathy (HCM). However, therapies that improve cardiac relaxation are scarce, partly due to a limited understanding of modulators of cardiomyocyte relaxation. We hypothesized that cardiac relaxation is regulated by multiple unidentified proteins and that dysregulation of kinases contributes to impaired relaxation in patients with HCM. METHODS: We optimized and increased the throughput of unloaded shortening measurements and screened a kinase inhibitor library in isolated adult cardiomyocytes from wild-type mice. One hundred fifty-seven kinase inhibitors were screened. To assess which kinases are dysregulated in patients with HCM and could contribute to impaired relaxation, we performed a tyrosine and global phosphoproteomics screen and integrative inferred kinase activity analysis using HCM patient myocardium. Identified hits from these 2 data sets were validated in cardiomyocytes from a homozygous MYBPC3c.2373insG HCM mouse model. RESULTS: Screening of 157 kinase inhibitors in wild-type (N=33) cardiomyocytes (n=24â563) resulted in the identification of 17 positive inotropes and 21 positive lusitropes, almost all of them novel. The positive lusitropes formed 3 clusters: cell cycle, EGFR (epidermal growth factor receptor)/IGF1R (insulin-like growth factor 1 receptor), and a small Akt (α-serine/threonine protein kinase) signaling cluster. By performing phosphoproteomic profiling of HCM patient myocardium (N=24 HCM and N=8 donors), we demonstrated increased activation of 6 of 8 proteins from the EGFR/IGFR1 cluster in HCM. We validated compounds from this cluster in mouse HCM (N=12) cardiomyocytes (n=2023). Three compounds from this cluster were able to improve relaxation in HCM cardiomyocytes. CONCLUSIONS: We showed the feasibility of screening for functional modulators of cardiomyocyte relaxation and contraction, parameters that we observed to be modulated by kinases involved in EGFR/IGF1R, Akt, cell cycle signaling, and FoxO (forkhead box class O) signaling, respectively. Integrating the screening data with phosphoproteomics analysis in HCM patient tissue indicated that inhibition of EGFR/IGF1R signaling is a promising target for treating impaired relaxation in HCM.</p
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