2,409 research outputs found

    Pouchitis.

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    Pouchitis is a major long-term complication of the continent ileostomy as well as the ileoanal pouch anastomosis. When diagnosed on the basis of clinical, endoscopic and histologic features, this syndrome has been demonstrated almost exclusively in patients with ulcerative colitis. The clinical course, the endoscopic findings and the histologic abnormalities resemble those of ulcerative colitis. The association with extra-intestinal manifestations further supports the hypothesis that pouchitis represents ulcerative colitis in the small bowel. All ileal reservoirs show bacterial overgrowth, especially of anaerobes. As a response to this altered intraluminal environment chronic inflammation and incomplete colonic metaplasia occur. The efficiency of metronidazole does suggest that bacteriological factors play an important role in the pathogenesis of pouchitis

    A cryogenic amplifier for fast real-time detection of single-electron tunneling

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    We employ a cryogenic High Electron Mobility Transistor (HEMT) amplifier to increase the bandwidth of a charge detection setup with a quantum point contact (QPC) charge sensor. The HEMT is operating at 1K and the circuit has a bandwidth of 1 MHz. The noise contribution of the HEMT at high frequencies is only a few times higher than that of the QPC shot noise. We use this setup to monitor single-electron tunneling to and from an adjacent quantum dot and we measure fluctuations in the dot occupation as short as 400 nanoseconds, 20 times faster than in previous work.Comment: 4 pages, 3 figure

    Josephson squelch filter for quantum nanocircuits

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    We fabricated and tested a squelch circuit consisting of a copper powder filter with an embedded Josephson junction connected to ground. For small signals (squelch-ON), the small junction inductance attenuates strongly from DC to at least 1 GHz, while for higher frequencies dissipation in the copper powder increases the attenuation exponentially with frequency. For large signals (squelch-OFF) the circuit behaves as a regular metal powder filter. The measured ON/OFF ratio is larger than 50dB up to 50 MHz. This squelch can be applied in low temperature measurement and control circuitry for quantum nanostructures such as superconducting qubits and quantum dots.Comment: Corrected and completed references 6,7,8. Updated some minor details in figure

    Sparling two-forms, the conformal factor and the gravitational energy density of the teleparallel equivalent of general relativity

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    It has been shown recently that within the framework of the teleparallel equivalent of general relativity (TEGR) it is possible to define the energy density of the gravitational field. The TEGR amounts to an alternative formulation of Einstein's general relativity, not to an alternative gravity theory. The localizability of the gravitational energy has been investigated in a number of space-times with distinct topologies, and the outcome of these analises agree with previously known results regarding the exact expression of the gravitational energy, and/or with the specific properties of the space-time manifold. In this article we establish a relationship between the expression for the gravitational energy density of the TEGR and the Sparling two-forms, which are known to be closely connected with the gravitational energy. We also show that our expression of energy yields the correct value of gravitational mass contained in the conformal factor of the metric field.Comment: 12 pages, Latex file, no figures, to be published in Gen. Rel. Gra

    Space-time defects and teleparallelism

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    We consider the class of space-time defects investigated by Puntigam and Soleng. These defects describe space-time dislocations and disclinations (cosmic strings), and are in close correspondence to the actual defects that arise in crystals and metals. It is known that in such materials dislocations and disclinations require a small and large amount of energy, respectively, to be created. The present analysis is carried out in the context of the teleparallel equivalent of general relativity (TEGR). We evaluate the gravitational energy of these space-time defects in the framework of the TEGR and find that there is an analogy between defects in space-time and in continuum material systems: the total gravitational energy of space-time dislocations and disclinations (considered as idealized defects) is zero and infinit, respectively.Comment: 22 pages, no figures, to appear in the Class. Quantum Gravit

    Beam heat load analysis with COLDDIAG: a cold vacuum chamber for diagnostics

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    The knowledge of the heat intake from the electron beam is essential to design the cryogenic layout of superconducting insertion devices. With the aim of measuring the beam heat load to a cold bore and understanding the responsible mechanisms, a cold vacuum chamber for diagnostics (COLDDIAG) has been built. The instrumentation comprises temperature sensors, pressure gauges, mass spectrometers and retarding field analyzers, which allow to study the beam heat load and the influence of the cryosorbed gas layer. COLDDIAG was installed in the storage ring of the Diamond Light Source from September 2012 to August 2013. During this time measurements were performed for a wide range of machine conditions, employing the various measuring capabilities of the device. Here we report on the analysis of the measured beam heat load, pressure and gas content, as well as the low energy charged particle flux and spectrum as a function of the electron beam parameters

    Enhancement of spatial coherence by surface plasmons

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    We report on a method to generate a stationary interference pattern from two independent optical sources, each illuminating a single slit in Young's interference experiment. The pattern arises as a result of the action of surface plasmons traveling between subwavelength slits milled in a metal film. The visibility of the interference pattern can be manipulated by tuning the wavelength of one of the optical sources. © 2007 Optical. Society of America
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