868 research outputs found
A sandpile model with tokamak-like enhanced confinement phenomenology
Confinement phenomenology characteristic of magnetically confined plasmas
emerges naturally from a simple sandpile algorithm when the parameter
controlling redistribution scalelength is varied. Close analogues are found for
enhanced confinement, edge pedestals, and edge localised modes (ELMs), and for
the qualitative correlations between them. These results suggest that tokamak
observations of avalanching transport are deeply linked to the existence of
enhanced confinement and ELMs.Comment: Manuscript is revtex (latex) 1 file, 7 postscript figures Revised
version is final version accepted for publication in PRL Revisions are mino
#Bieber + #Blast = #BieberBlast: Early Prediction of Popular Hashtag Compounds
Compounding of natural language units is a very common phenomena. In this
paper, we show, for the first time, that Twitter hashtags which, could be
considered as correlates of such linguistic units, undergo compounding. We
identify reasons for this compounding and propose a prediction model that can
identify with 77.07% accuracy if a pair of hashtags compounding in the near
future (i.e., 2 months after compounding) shall become popular. At longer times
T = 6, 10 months the accuracies are 77.52% and 79.13% respectively. This
technique has strong implications to trending hashtag recommendation since
newly formed hashtag compounds can be recommended early, even before the
compounding has taken place. Further, humans can predict compounds with an
overall accuracy of only 48.7% (treated as baseline). Notably, while humans can
discriminate the relatively easier cases, the automatic framework is successful
in classifying the relatively harder cases.Comment: 14 pages, 4 figures, 9 tables, published in CSCW (Computer-Supported
Cooperative Work and Social Computing) 2016. in Proceedings of 19th ACM
conference on Computer-Supported Cooperative Work and Social Computing (CSCW
2016
Electronic structure and ferroelectricity in SrBi2Ta2O9
The electronic structure of SrBi2Ta2O9 is investigated from first-principles,
within the local density approximation, using the full-potential linearized
augmented plane wave (LAPW) method. The results show that, besides the large
Ta(5d)-O(2p) hybridization which is a common feature of the ferroelectric
perovskites, there is an important hybridization between bismuth and oxygen
states. The underlying static potential for the ferroelectric distortion and
the primary source for ferroelectricity is investigated by a lattice-dynamics
study using the Frozen Phonon approach.Comment: 17 pages, 7 figures. Phys. Rev. B, in pres
Auger Recombination in Semiconductor Quantum Wells
The principal mechanisms of Auger recombination of nonequilibrium carriers in
semiconductor heterostructures with quantum wells are investigated. It is shown
for the first time that there exist three fundamentally different Auger
recombination mechanisms of (i) thresholdless, (ii) quasi-threshold, and (iii)
threshold types. The rate of the thresholdless Auger process depends on
temperature only slightly. The rate of the quasi-threshold Auger process
depends on temperature exponentially. However, its threshold energy essentially
varies with quantum well width and is close to zero for narrow quantum wells.
It is shown that the thresholdless and the quasi-threshold Auger processes
dominate in narrow quantum wells, while the threshold and the quasi-threshold
processes prevail in wide quantum wells. The limiting case of a
three-dimensional (3D)Auger process is reached for infinitely wide quantum
wells. The critical quantum well width is found at which the quasi-threshold
and threshold Auger processes merge into a single 3D Auger process. Also
studied is phonon-assisted Auger recombination in quantum wells. It is shown
that for narrow quantum wells the act of phonon emission becomes resonant,
which in turn increases substantially the coefficient of phonon-assisted Auger
recombination. Conditions are found under which the direct Auger process
dominates over the phonon-assisted Auger recombination at various temperatures
and quantum well widths.Comment: 38 pages, 7 figure
Isoscalar dipole coherence at low energies and forbidden E1 strength
In 16O and 40Ca an isoscalar, low-energy dipole transition (IS-LED)
exhausting approximately 4% of the isoscalar dipole (ISD) energy-weighted sum
rule is experimentally known, but conspicuously absent from recent theoretical
investigations of ISD strength. The IS-LED mode coincides with the so-called
isospin-forbidden E1 transition. We report that for N=Z nuclei up to 100Sn the
fully self-consistent Random-Phase-Approximation with finite-range forces,
phenomenological and realistic, yields a collective IS-LED mode, typically
overestimating its excitation energy, but correctly describing its IS strength
and electroexcitation form factor. The presence of E1 strength is solely due to
the Coulomb interaction between the protons and the resulting isospin-symmetry
breaking. The smallness of its value is related to the form of the transition
density, due to translational invariance. The calculated values of E1 and ISD
strength carried by the IS-LED depend on the effective interaction used.
Attention is drawn to the possibility that in N-not-equal-Z nuclei this
distinct mode of IS surface vibration can develop as such or mix strongly with
skin modes and thus influence the pygmy dipole strength as well as the ISD
strength function. In general, theoretical models currently in use may be unfit
to predict its precise position and strength, if at all its existence.Comment: 9 pages, 6 figures, EPJA submitte
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer
Background: Recent studies have suggested that fatty acid oxidation (FAO) is a key metabolic pathway for the growth of triple negative breast cancers (TNBCs), particularly those that have high expression of MYC. However, the underlying mechanism by which MYC promotes FAO remains poorly understood. Methods: We used a combination of metabolomics, transcriptomics, bioinformatics, and microscopy to elucidate a potential mechanism by which MYC regulates FAO in TNBC. Results: We propose that MYC induces a multigenic program that involves changes in intracellular calcium signalling and fatty acid metabolism. We determined key roles for fatty acid transporters (CD36), lipases (LPL), and kinases (PDGFRB, CAMKK2, and AMPK) that each contribute to promoting FAO in human mammary epithelial cells that express oncogenic levels of MYC. Bioinformatic analysis further showed that this multigenic program is highly expressed and predicts poor survival in the claudin-low molecular subtype of TNBC, but not other subtypes of TNBCs, suggesting that efforts to target FAO in the clinic may best serve claudin-low TNBC patients. Conclusion: We identified critical pieces of the FAO machinery that have the potential to be targeted for improved treatment of patients with TNBC, especially the claudin-low molecular subtype
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