53 research outputs found

    Effective Regge QCD

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    A new framework for a high energy limit of quantum gauge field theories is introduced. Its potency is illustrated on a new derivation of the reggeization of the gluon.Comment: Latex, 9 pages + 2 figures as PS-file, extended version, to appear in Phys. Rev. Let

    From differentiating metabolites to biomarkers

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    The current developments in metabolomics and metabolic profiling technologies have led to the discovery of several new metabolic biomarkers. Finding metabolites present in significantly different levels between sample sets, however, does not necessarily make these metabolites useful biomarkers. The route to valid and applicable biomarkers (biomarker qualification) is long and demands a significant amount of work. In this overview, we critically discuss the current state-of-the-art of metabolic biomarker discovery, with highlights and shortcomings, and suggest a pathway to clinical usefulness

    Diagnosis of Partial Body Radiation Exposure in Mice Using Peripheral Blood Gene Expression Profiles

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    In the event of a terrorist-mediated attack in the United States using radiological or improvised nuclear weapons, it is expected that hundreds of thousands of people could be exposed to life-threatening levels of ionizing radiation. We have recently shown that genome-wide expression analysis of the peripheral blood (PB) can generate gene expression profiles that can predict radiation exposure and distinguish the dose level of exposure following total body irradiation (TBI). However, in the event a radiation-mass casualty scenario, many victims will have heterogeneous exposure due to partial shielding and it is unknown whether PB gene expression profiles would be useful in predicting the status of partially irradiated individuals. Here, we identified gene expression profiles in the PB that were characteristic of anterior hemibody-, posterior hemibody- and single limb-irradiation at 0.5 Gy, 2 Gy and 10 Gy in C57Bl6 mice. These PB signatures predicted the radiation status of partially irradiated mice with a high level of accuracy (range 79–100%) compared to non-irradiated mice. Interestingly, PB signatures of partial body irradiation were poorly predictive of radiation status by site of injury (range 16–43%), suggesting that the PB molecular response to partial body irradiation was anatomic site specific. Importantly, PB gene signatures generated from TBI-treated mice failed completely to predict the radiation status of partially irradiated animals or non-irradiated controls. These data demonstrate that partial body irradiation, even to a single limb, generates a characteristic PB signature of radiation injury and thus may necessitate the use of multiple signatures, both partial body and total body, to accurately assess the status of an individual exposed to radiation

    The infrared structure of gauge theory amplitudes in the high-energy limit

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    We develop an approach to the high-energy limit of gauge theories based on the universal properties of their infrared singularities. Our main tool is the dipole formula, a compact ansatz for the all-order infrared singularity structure of scattering amplitudes of massless partons. By taking the high-energy limit, we show that the dipole formula implies Reggeization of infrared-singular contributions to the amplitude, at leading logarithmic accuracy, for the exchange of arbitrary color representations in the cross channel. We observe that the real part of the amplitude Reggeizes also at next-to-leading logarithmic order, and we compute the singular part of the two-loop Regge trajectory, which is universally expressed in terms of the cusp anomalous dimension. Our approach provides tools to study the high-energy limit beyond the boundaries of Regge factorization: thus we show that Reggeization generically breaks down at next-to-next-to-leading logarithmic accuracy, and provide a general expression for the leading Reggeization-breaking operator. Our approach applies to multiparticle amplitudes in multi-Regge kinematics, and it also implies new constraints on possible corrections to the dipole formula, based on the Regge limit

    Does emigration reduce corruption?

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    © 2017, The Author(s). We study the effects of emigration on bribery experience and attitudes towards corruption in the migrants’ countries of origin. Using data from the Gallup Balkan Monitor survey and instrumental variable analysis, we find that having relatives abroad reduces the likelihood of bribing public officials, renders bribe-taking behavior by public officials less acceptable, and reduces the likelihood of being asked for bribes by public officials. Receiving monetary remittances does not change the beneficial effects regarding bribe paying and attitudes toward corruption; however, remittances counteract the beneficial effect on bribe solicitations by public officials. Overall, our findings support the conjecture that migration contributes to the transfer of norms and practices from destination to source countries

    Tomato (Solanum lycopersicum L.) in the service of biotechnology

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    Ethical assumptions of sustainable development education

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    Artykuł jest próbą prezentacji głównych założen etycznych stanowiących podstawę edukacji na rzecz zrównoważonego rozwoju. Uwaga skoncentrowana jest tu na następujacych kwestiach: - prezentacji ogólnych założenia edukacji na rzecz zrównoważonego rozwoju; - filozoficznych podstaw idei zrównoważonego rozwoju; - aksjologicznych podstaw zrównoważonego rozwoju; wartość życia, zdrowia, sprawiedliwosci, odpowiedzialności, powściągliwości i solidarnosci. - roli i znaczenia etyki środowiskowej w koncepcji zrównoważonego rozwoju; - poziomy działań w zakresie edukacji środowiskowej jako składnika edukacji na rzecz zrównoważonego rozwoju: kognitywny, wolitywny i behawioralnyThe article is trying to present main ethical ideas supporting the education for sustainable development. The interest is focused on the following topics. - presentation of general assumptions of sustainable development education. - philosophical basis of the idea of sustainable development, values of life, health, justice, responsibility, moderateness and solidarity. - the role and importance of developmental ethics for the idea of sustainable development. - the cognitive, volitive and behavioral levels of action in the scope of developmental education being an element of education for sustainable development

    Origin and development of ecological philosophy

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    Niniejsza wypowiedz stawia sobie za zadanie przedstawienie narodzin i rozwoju filozofii ekologicznej i etyki środowiskowej. Dyscypliny te nawiazuja do wielowiekowego dorobku mysli filozoficznej, głównie filozofii przyrody, ale w dojrzałej postaci ukonstytuowały sie dopiero na przełomie lat 60. i 80. XX w. w Stanach Zjednoczonych. Artykuł przywołuje XIX wieczne inspiracje myślenia nakierowanego na ochronę środowiska przyrodniczego (R.W. Emerson, H.D. Thoreau), a następnie ukazuje etapy rozwoju filozofii ekologicznej i etyki środowiska, główne stanowiska i ich reprezentantów takich jak: J. Muir, Aldo Leopold, J. Baird Callicot, Holems Rolston III, P.W. Taylor, J. Passmore, Arne Naess, H. Skolimowski i inni. W drugiej czesci niniejszego opracowania przedstawiono narodziny i rozwój filozofii i etyki srodowiskowej w Polsce. Ukazano kierunki i stanowiska w ramach filozofii i etyki srodowiskowej a take głównych ich reprezentantów. Scharakteryzowano take dorobek polskiej mysli ekofilozoficznej.The above text tries to describe the birth and developoment of environmental philosophy and environmental ethics. These disciplines refer to the legacy of many centuries of philosophical thought, mainly the philosophy of nature; however, these disciplines acquired the developed form as late as in the period between 1960s and 1980s in the United States. The article describes 19th century influences that inspired thinking about the protection of natural environment (R.W. Emerson, H.D. Thoreau), and then shows the stages of development of evironmental philosophy and environmental ethics, mainly the standpoints and their representatives such as J. Muir, Aldo Leopold, J. Baird Callicot, Holems Rolston III, P.W. Taylor, J. Passmore, Arne Naess, H. Skolimowski and others. The other part of this article deals with the emergence and development of environmental philosophy and environmental ethics in Poland. It pinpoints the directions and standpoints of environmental philosophy and environmental ethics, presents their main representatives and also describes the achievements of Polish ecophilosophical though
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