49,186 research outputs found
The Density of States and the Spectral Shift Density of Random Schroedinger Operators
In this article we continue our analysis of Schroedinger operators with a
random potential using scattering theory. In particular the theory of Krein's
spectral shift function leads to an alternative construction of the density of
states in arbitrary dimensions. For arbitrary dimension we show existence of
the spectral shift density, which is defined as the bulk limit of the spectral
shift function per unit interaction volume. This density equals the difference
of the density of states for the free and the interaction theory. This extends
the results previously obtained by the authors in one dimension. Also we
consider the case where the interaction is concentrated near a hyperplane.Comment: 1 figur
Cug2 is essential for normal mitotic control and CNS development in zebrafish.
Background:
We recently identified a novel oncogene, Cancer-upregulated gene 2 (CUG2), which is essential for kinetochore formation and promotes tumorigenesis in mammalian cells. However, the in vivo function of CUG2 has not been studied in animal models.
Results:
To study the function of CUG2 in vivo, we isolated a zebrafish homologue that is expressed specifically in the proliferating cells of the central nervous system (CNS). Morpholino-mediated knockdown of cug2 resulted in apoptosis throughout the CNS and the development of neurodegenerative phenotypes. In addition, cug2-deficient embryos contained mitotically arrested cells displaying abnormal spindle formation and chromosome misalignment in the neural plate.
Conclusions:
Therefore, our findings suggest that Cug2 is required for normal mitosis during early neurogenesis and has functions in neuronal cell maintenance, thus demonstrating that the cug2 deficient embryos may provide a model system for human neurodegenerative disorders
Boltzmann Suppression of Interacting Heavy Particles
Matsumoto and Yoshimura have recently argued that the number density of heavy
particles in a thermal bath is not necessarily Boltzmann-suppressed for T << M,
as power law corrections may emerge at higher orders in perturbation theory.
This fact might have important implications on the determination of WIMP relic
densities. On the other hand, the definition of number densities in a
interacting theory is not a straightforward procedure. It usually requires
renormalization of composite operators and operator mixing, which obscure the
physical interpretation of the computed thermal average. We propose a new
definition for the thermal average of a composite operator, which does not
require any new renormalization counterterm and is thus free from such
ambiguities. Applying this definition to the model of Matsumoto and Yoshimura
we find that it gives number densities which are Boltzmann-suppressed at any
order in perturbation theory. We discuss also heavy particles which are
unstable already at T=0, showing that power law corrections do in general
emerge in this case.Comment: 7 pages, 5 figures. New section added, with the discussion of the
case of an unstable heavy particle. Version to appear on Phys. Rev.
Localization in a Disordered Multi-Mode Waveguide with Absorption or Amplification
An analytical and numerical study is presented of transmission of radiation
through a multi-mode waveguide containing a random medium with a complex
dielectric constant . Depending on the sign of
, the medium is absorbing or amplifying. The transmitted intensity
decays exponentially as the waveguide length
, regardless of the sign of . The localization length
is computed as a function of the mean free path , the absorption or
amplification length , and the number of modes in the waveguide
. The method used is an extension of the Fokker-Planck approach of Dorokhov,
Mello, Pereyra, and Kumar to non-unitary scattering matrices. Asymptotically
exact results are obtained for and . An approximate
interpolation formula for all agrees reasonably well with numerical
simulations.Comment: 13 pages, RevTeX, 1 postscript figur
New Kinetic Equation for Pair-annihilating Particles: Generalization of the Boltzmann Equation
A convenient form of kinetic equation is derived for pair annihilation of
heavy stable particles relevant to the dark matter problem in cosmology. The
kinetic equation thus derived extends the on-shell Boltzmann equation in a most
straightforward way, including the off-shell effect. A detailed balance
equation for the equilibrium abundance is further analyzed. Perturbative
analysis of this equation supports a previous result for the equilibrium
abundance using the thermal field theory, and gives the temperature power
dependence of equilibrium value at low temperatures. Estimate of the relic
abundance is possible using this new equilibrium abundance in the sudden
freeze-out approximation.Comment: 19 pages, LATEX file with 2 PS figure
Temperature Power Law of Equilibrium Heavy Particle Density
A standard calculation of the energy density of heavy stable particles that
may pair-annihilate into light particles making up thermal medium is performed
to second order of coupling, using the technique of thermal field theory. At
very low temperatures a power law of temperature is derived for the energy
density of the heavy particle. This is in sharp contrast to the exponentially
suppressed contribution estimated from the ideal gas distribution function. The
result supports a previous dynamical calculation based on the Hartree
approximation, and implies that the relic abundance of dark matter particles is
enhanced compared to that based on the Boltzmann equation.Comment: 12 pages, LATEX file with 6 PS figure
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