High-strength tungsten alloy with improved ductility

Alloy combines superior strength at elevated temperatures with improved ductility at lower temperatures relative to unalloyed tungsten. Composed of tungsten, rhenium, hafnium, and carbon, the alloy is prepared by consumable electrode vacuum arc-melting and can be fabricated into rod, plate, and sheet

Characterization of Yellow Family Proteins in \u3ci\u3eGryllus bimaculatus\u3c/i\u3e

[Abstract embargoed.

GOVERNMENT PATENTING AND TECHNOLOGY TRANSFER

Intellectual property rights such as patents protect new inventions from imitation and competition. Patents' major objective is to provide incentives for invention, sacrificing short-term market efficiency for long-term economic gains. Although patents are primarily granted to private firms, policy changes over the last 25 years have resulted in greater use of patenting by the public sector. This study examines government patenting behavior by analyzing case studies of patenting and licensing by the Agricultural Research Service (ARS) of the U.S. Department of Agriculture. ARS uses patenting and licensing as a means of technology transfer in cases in which a technology requires additional development by a private sector partner to yield a marketable product. Licensing revenue is not a major motivation for ARS patenting. More widespread use of patenting and licensing by ARS has not reduced the use of traditional instruments of technology transfer such as scientific publication. Once the decision has been made to patent and license a technology, the structure of the licensing agreement affects technology transfer outcomes. As commercial partners gain experience with the technology and learn more about the market, mutually advantageous revisions to license terms can maintain the incentives through which private companies distribute the benefits of public research.patents, licenses, intellectual property rights, technology transfer, Agricultural Research Service, agricultural research and development, Research and Development/Tech Change/Emerging Technologies,

COMPETITIVE GRANTS AND THE FUNDING OF AGRICULTURAL RESEARCH IN THE U.S.

To increase the efficiency of the public agricultural R&D system, expanded use of competitive grants to fund state institutions has been advocated. This paper characterizes different funding instruments and empirically assesses the effects of changes in mechanism use. Factors associated with greater levels of competitive grants are modeled.Research and Development/Tech Change/Emerging Technologies,

Assessing the Benefits of Public Research Within an Economic Framework: The Case of USDA's Agricultural Research Service

Evaluation of publicly funded research can help provide accountability and prioritize programs. In addition, Federal intramural research planning generally involves an institutional assessment of the appropriate Federal role, if any, and whether the research should be left to others, such as universities or the private sector. Many methods of evaluation are available, peer review—used primarily for establishing scientific merit—being the most common. Economic analysis focuses on quantifying ultimate research outcomes, whether measured in goods with market prices or in nonmarket goods such as environmental quality or human health. However, standard economic techniques may not be amenable for evaluating some important public research priorities or for institutional assessments. This report reviews quantitative methods and applies qualitative economic reasoning and stakeholder interviewing methods to the evaluation of economic benefits of Federal intramural research using three case studies of research conducted by USDA’s Agricultural Research Service (ARS). Differences among the case studies highlight the need to select suitable assessment techniques from available methodologies, the limited scope for comparing assessment results across programs, and the inherent difficulty in quantifying benefits in some research areas. When measurement and attribution issues make it difficult to quantify these benefits, the report discusses how qualitative insights based on economic concepts can help research prioritization.Agricultural Research Service, Federal intramural research, publicly funded research, Environmental Economics and Policy, Food Consumption/Nutrition/Food Safety, Livestock Production/Industries, Productivity Analysis,

The mechanical response of semiflexible networks to localized perturbations

Previous research on semiflexible polymers including cytoskeletal networks in cells has suggested the existence of distinct regimes of elastic response, in which the strain field is either uniform (affine) or non-uniform (non-affine) under external stress. Associated with these regimes, it has been further suggested that a new fundamental length scale emerges, which characterizes the scale for the crossover from non-affine to affine deformations. Here, we extend these studies by probing the response to localized forces and force dipoles. We show that the previously identified nonaffinity length [D.A. Head et al. PRE 68, 061907 (2003).] controls the mesoscopic response to point forces and the crossover to continuum elastic behavior at large distances.Comment: 16 pages, 18 figures; substantial changes to text and figures to clarify the crossover to continuum elasticity and the role of finite-size effect

Research Investments and Market Structure in the Food Processing, Agricultural Input, and Biofuel Industries Worldwide

Meeting growing global demand for food, fiber, and biofuel requires robust investment in agricultural research and development (R&D) from both public and private sectors. This study examines global R&D spending by private industry in seven agricultural input sectors, food manufacturing, and biofuel and describes the changing structure of these industries. In 2007 (the latest year for which comprehensive estimates are available), the private sector spent 19.7 billion on food and agricultural research (56 percent in food manufacturing and 44 percent in agricultural input sectors) and accounted for about half of total public and private spending on food and agricultural R&D in high-income countries. In R&D related to biofuel, annual private-sector investments are estimated to have reached 1.47 billion worldwide by 2009. Incentives to invest in R&D are influenced by market structure and other factors. Agricultural input industries have undergone significant structural change over the past two decades, with industry concentration on the rise. A relatively small number of large, multinational firms with global R&D and marketing networks account for most R&D in each input industry. Rising market concentration has not generally been associated with increased R&D investment as a percentage of industry sales.agricultural biotechnology, agricultural chemicals, agricultural inputs, animal breeding, animal health, animal nutrition, aquaculture, biofuel, concentration ratio, crop breeding, crop protection, farm machinery, fertilizers, Herfindahl index, globalization, market share, market structure, research intensity, seed improvement, Productivity Analysis,

Bolus clearance in esophagogastric junction outflow obstruction is associated with strength of peristalsis

BackgroundA manometric diagnosis of esophagogastric junction outflow obstruction (EGJOO) without a mechanical cause creates a therapeutic conundrum. The aim of this study was to assess esophageal bolus clearance in EGJOO and assess manometric factors associated with clearance in EGJOO.MethodsBolus clearance was assessed using line‐tracing method and contour method to determine Complete Bolus Transit (CBT) and Functional Clearance (FC), respectively, on combined High‐Resolution Impedance Manometry (HRIM). HRIM studies of EGJOO patients, as well as a sample of achalasia types I‐III and asymptomatic controls, were retrospectively analyzed. In EGJOO, associations between Integrated Relaxation Pressure (IRP) or Distal Contractile Integral (DCI) and clearance were assessed using receiver‐operating‐characteristic (ROC) curves.Key ResultsSeventy‐five EGJOO, 28 achalasia, and 11 normal subjects were included. Agreement between CBT and FC was good (Kappa=0.75). CBT across swallows in each group was as follows: type I achalasia: 14%, type II achalasia: 8%, type III achalasia: 61%, EGJOO: 86%, and normal: 98% (p values .023, .006, and 610 mmHg‐s‐cm (accuracy 87.7%, P=.004). Complete Bolus Transit( CBT) across individual swallows was 97.8% when DCI>884 mmHg‐s‐cm (accuracy 81.9%, P900 mmHg‐s‐cm.Esophagogastric junction outflow obstruction (EGJOO) is a manometric diagnosis with unclear clinical significance. We studied bolus clearance in EGJOO, including in relationship to Distal Contractile Integral (DCI) and Integrated Relaxation Pressure (IRP). We found that intact peristalsis defined as a DCI of greater than 900 mmHg‐s‐cm is associated with complete bolus transit.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138211/1/nmo13093_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138211/2/nmo13093.pd