Music symbol recognition

This paper focuses on optical music recognition (OMR) system that recognizes the musical symbols on a digitized music sheet and converts them into symbolic music representation. Two main stages are distinguished ? pre-processing and symbol analysis. In the pre-processing stage, staves are detected and removed; while in the symbol analysis stage, each musical symbol is recognized and analyzed. The musical semantics are then determined and converted into symbolic music representation stored in text form

XAX: a multi-ton, multi-target detection system for dark matter, double beta decay and pp solar neutrinos

A multi-target detection system XAX, comprising concentric 10 ton targets of 136Xe and 129/131Xe, together with a geometrically similar or larger target of liquid Ar, is described. Each is configured as a two-phase scintillation/ionization TPC detector, enhanced by a full 4pi array of ultra-low radioactivity Quartz Photon Intensifying Detectors (QUPIDs) replacing the conventional photomultipliers for detection of scintillation light. It is shown that background levels in XAX can be reduced to the level required for dark matter particle (WIMP) mass measurement at a 10^-10 pb WIMP-nucleon cross section, with single-event sensitivity below 10^-11 pb. The use of multiple target elements allows for confirmation of the A^2 dependence of a coherent cross section, and the different Xe isotopes provide information on the spin-dependence of the dark matter interaction. The event rates observed by Xe and Ar would modulate annually with opposite phases from each other for WIMP mass >~100 GeV/c^2. The large target mass of 136Xe and high degree of background reduction allow neutrinoless double beta decay to be observed with lifetimes of 10^27-10^28 years, corresponding to the Majorana neutrino mass range 0.01-0.1 eV, the most likely range from observed neutrino mass differences. The use of a 136Xe-depleted 129/131Xe target will also allow measurement of the pp solar neutrino spectrum to a precision of 1-2%.Comment: 16 pages with 17 figure

Experimental study of anisotropy and non-coaxiality of granular solids

Previous experimental studies of anisotropy and non-coaxiality by using the hollow cylindrical apparatus are mainly focused on granular soils, which feature irregular particle shapes and non-uniform particle size distributions. This paper experimentally investigates these two characteristics on assemblages of particulate materials with regular particle shapes and uniform particle sizes. These assemblages are made from spherical, cylindrical and cubical particles, with an increasing order of particle angularity. Two types of loading paths in the hollow cylindrical apparatus are applied. One is the monotonic loading path with a range of fixed angles of major principal stress with respect to the horizontal bedding plan, used to investigate the anisotropy of materials. The other is the path of pure principal stress rotations, used to study the non-coaxiality. The experimental results indicate that these three materials exhibit a strong anisotropy and non-coaxiality. Their stress–strain responses are dependent on the orientation of major principal stress. The non-coaxiality is a function of stress ratio. In addition, there is a noticeable trend that these two characteristics are dependent on the angularity of particles. The more angular the particles are, the greater anisotropy and non-coaxiality take place

Self-reported illness among Boston-area international travelers: A prospective study

This is the Accepted Manuscript version and was published in final edited form as: Travel Med Infect Dis. 2016 ; 14(6): 604–613. doi:10.1016/j.tmaid.2016.09.009.BACKGROUND: The Boston Area Travel Medicine Network surveyed travelers on travel-related health problems. METHODS: Travelers were recruited 2009-2011 during pre-travel consultation at three clinics. The investigation included pre-travel data, weekly during-travel diaries, and a post-travel questionnaire. We analyzed demographics, trip characteristics, health problems experienced, and assessed the relationship between influenza vaccination, influenza prevention advice, and respiratory symptoms. RESULTS:Of 987 enrolled travelers, 628 (64%) completed all surveys, of which 400 (64%) reported health problems during and/or after travel; median trip duration was 12 days. Diarrhea affected the most people during travel (172) while runny/stuffy nose affected the most people after travel (95). Of those with health problems during travel, 25% stopped or altered plans; 1% were hospitalized. After travel, 21% stopped planned activities, 23% sought physician or other health advice; one traveler was hospitalized. Travelers who received influenza vaccination and influenza prevention advice had lower rates of respiratory symptoms than those that received influenza prevention advice alone (18% vs 28%, P = 0.03). CONCLUSIONS:A large proportion of Boston-area travelers reported health problems despite pre-travel consultation, resulting in inconveniences. The combination of influenza prevention advice and influenza immunization was associated with fewer respiratory symptoms than those who received influenza prevention advice alone

Numerical Study of the Behaviour of Wall Shear Stress in Pulsatile Stenotic Flows

This paper presents a numerical study of pulsatile flow through an axisymmetric stenosed artery. Numerical calculations of the incompressible Navier-Stokes equations were carried out in an axisymmetric geometry to investigate how the wall shear stress (WSS) is affected by varying levels of stenosis contractions and pulse periods (reduced velocity). It is found that the distribution and strength of the WSS is closely correlated with the position of the vortex ring formed at the stenosis. Each vortex ring generates high WSS at the stenosis walls and this high WSS propagate downstream with the vortex ring. As the vortex ring convects downstream, it loses its strength due to viscous effects and WSS decreases in magnitude. In general, the strength of the vortex ring increases with increasing stenosis levels which leads to higher WSS values on the walls. The effect of smaller pulse period is to reduce the distance between the vortex rings, thus increasing the spatial variation of WSS along the stenosed artery

A brain-derived MeCP2 complex supports a role for MeCP2 in RNA processing

Mutations in MECP2 (methyl-CpG-binding protein 2) are linked to the severe postnatal neurodevelopmental disorder RTT (Rett syndrome). MeCP2 was originally characterized as a transcriptional repressor that preferentially bound methylated DNA; however, recent results indicate MeCP2 is a multifunctional protein. MeCP2 binding is now associated with certain expressed genes and involved in nuclear organization as well, indicating that its gene regulatory function is context-dependent. In addition, MeCP2 is proposed to regulate mRNA splicing and a mouse model for RTT shows aberrant mRNA splicing. To further understand MeCP2 and potential roles in RTT pathogenesis, we have employed a biochemical approach to identify the MeCP2 protein complexes present in the mammalian brain. We show that MeCP2 exists in at least four biochemically distinct pools in the brain and characterize one novel brain-derived MeCP2 complex that contains the splicing factor Prpf3 (pre-mRNA processing factor 3). MeCP2 directly interacts with Prpf3 in vitro and in vivo and many MECP2 RTT truncations disrupt the MeCP2-Prpf3 complex. In addition, MeCP2 and Prpf3 associate in vivo with mRNAs from genes known to be expressed when their promoters are associated with MeCP2. These results support a role for MeCP2 in mRNA biogenesis and suggest an additional mechanism for RTT pathophysiology

High Aspect Pattern Formation by Integration of Micro Inkjetting and Electroless Plating

This paper reports on formation of high aspect micro patterns on low temperature co-fired ceramic (LTCC) substrates by integrating micro inkjetting with electroless plating. Micro inkjetting was realized by using an inkjetting printer that ejects ink droplets from a printhead. This printhead consists of a glass nozzle with a diameter of 50 micrometers and a piezoelectric transducer that is coated on the nozzle. The silver colloidal solution was inkjetted on a sintered CT800 ceramic substrate, followed by curing at 200 degrees C for 60 minutes. As a result, the silver trace with a thickness of 200 nm was obtained. The substrate, with the ejected silver thin film as the seed layer, was then immersed into a preinitiator solution to coat a layer of palladium for enhancing the deposition of nickel. Electroless nickel plating was successfully conducted at a rate of 0.39 micrometers /min, and the thickness of traces was plated up to 84 micrometers. This study demonstrates that the integration of inkjetting with plating is an effective method to form high aspect patterns at the demand location.Comment: Submitted on behalf of EDA Publishing Association (http://irevues.inist.fr/handle/2042/16838