Conditions for free magnetic monopoles in nanoscale square arrays of dipolar spin ice

We study a modified frustrated dipolar array recently proposed by M\"{o}ller and Moessner [Phys. Rev. Lett. \textbf{96}, 237202 (2006)], which is based on an array manufactured lithographically by Wang \emph{et al.} [Nature (London) \textbf{439}, 303 (2006)] and consists of introducing a height offset $h$ between islands (dipoles) pointing along the two different lattice directions. The ground-states and excitations are studied as a function of $h$. We have found, in qualitative agreement with the results of M\"{o}ller and Moessner, that the ground-state changes for $h>h_{1}$, where $h_{1}= 0.444a$ ($a$ is the lattice parameter or distance between islands). In addition, the excitations above the ground-state behave like magnetic poles but confined by a string, whose tension decreases as $h$ increases, in such a way that for $h\approx h_1$ its value is around 20 times smaller than that for $h=0$. The system exhibits an anisotropy in the sense that the string tension and magnetic charge depends significantly on the directions in which the monopoles are separated. In turn, the intensity of the magnetic charge abruptly changes when the monopoles are separated along the direction of the longest axis of the islands. Such a gap is attributed to the transition from the anti to the ferromagnetic ground-state when $h=h_1$.Comment: 6 pages, 7 figures. Published versio

Nambu monopoles interacting with lattice defects in two-dimensional artificial square spin ice

The interactions between an excitation (similar to a pair of Nambu monopoles) and a lattice defect are studied in an artificial two-dimensional square spin ice. This is done by considering a square array of islands containing only one island different from all others. This difference is incorporated in the magnetic moment (spin) of the "imperfect" island and several cases are studied, including the special situation in which this distinct spin is zero (vacancy). We have shown that the two extreme points of a malformed island behave like two opposite magnetic charges. Then, the effective interaction between a pair of Nambu monopoles with the deformed island is a problem involving four magnetic charges (two pairs of opposite poles) and a string. We also sketch the configuration of the field lines of these four charges to confirm this picture. The influence of the string on this interaction decays rapidly with the string distance from the defect.Comment: 7 pages, 13 figure

On thermalization of magnetic nano-arrays at fabrication

We propose a model to predict and control the statistical ensemble of magnetic degrees of freedom in Artificial Spin Ice (ASI) during thermalized adiabatic growth. We predict that as-grown arrays are controlled by the temperature at fabrication and by their lattice constant, and that they can be described by an effective temperature. If the geometry is conducive to a phase transition, then the lowest temperature phase is accessed in arrays of lattice constant smaller than a critical value, which depends on the temperature at deposition. Alternatively, for arrays of equal lattice constant, there is a temperature threshold at deposition and the lowest temperature phase is accessed for fabrication temperatures {\it larger rather than smaller} than this temperature threshold. Finally we show how to define and control the effective temperature of the as-grown array and how to measure critical exponents directly. We discuss the role of kinetics at the critical point, and applications to experiments, in particular to as-grown thermalized square ASI, and to magnetic monopole crystallization in as-grown honeycomb ASI.Comment: 14 pages, 2 figures. A theoretical approach to experimental results reported in: Morgan J P, Stein A, Langridge S and Marrows C (2010) Nature Physics 7 7

Dynamics and hysteresis in square lattice artificial spin-ice

Dynamical effects under geometrical frustration are considered in a model for artificial spin ice on a square lattice in two dimensions. Each island of the spin ice has a three-component Heisenberg-like dipole moment subject to shape anisotropies that influence its direction. The model has real dynamics, including rotation of the magnetic degrees of freedom, going beyond the Ising-type models of spin ice. The dynamics is studied using a Langevin equation solved via a second order Heun algorithm. Thermodynamic properties such as the specific heat are presented for different couplings. A peak in specific heat is related to a type of melting-like phase transition present in the model. Hysteresis in an applied magnetic field is calculated for model parameters where the system is able to reach thermodynamic equilibrium.Comment: Revised versio

Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines

The series of new acetylenic thioquinolines containing propargyl, 4-chloro-2-butynyl, and 4-acyloxy-2-butynyl groups have been prepared and tested for antiproliferative activity in vitro against human [SW707 (colorectal adenocarcinoma), CCRF/CEM (leukemia), T47D (breast cancer)] and murine [P388 (leukemia), B16 (melanoma)] cancer lines. Most of the obtained compounds exhibited antiproliferative activity, especially compounds 8, 12, and 21 showed the ID50 values ranging from 0.4 to 3.8 μg/ml comparable to that of cisplatin used as reference compounds

Thermodynamics of elementary excitations in artificial magnetic square ice

We investigate the thermodynamics of artificial square spin ice systems assuming only dipolar interactions among the islands that compose the array. The emphasis is given on the effects of the temperature on the elementary excitations (magnetic monopoles and their Dirac strings). By using Monte Carlo techniques we calculate the specific heat, the density of poles and their average separation as functions of temperature. The specific heat and average separation between monopoles and antimonopoles exhibit a sharp peak and a local maximum, respectively, at the same temperature, $T_{p}\approx 7.2D/k_{B}$ (here, $D$ is the strength of the dipolar interaction and $k_{B}$ is the Boltzmann constant). As the lattice size is increased, the amplitude of these features also increases but very slowly. Really, the specific heat and the maximum in the average separation $d_{max}$ between oppositely charged monopoles increase logarithmically with the system size, indicating that completely isolated charges could be found only at the thermodynamic limit. In general, the results obtained here suggest that, for temperatures $T \geq T_{p}$, these systems may exhibit a phase with separated monopoles, although the quantity $d_{max}$ should not be larger than a few lattice spacings for viable artificial materials.Comment: 7 pages, 9 figure