Influence of a monitored aerobic training and a low-energy diet on serum leptin concentration in obese women

The study focused on the influence of a 9-week monitored energy deficit on serum leptin level in 16 obese women. Additionally, measurements of body components and total cholesterol (CHO), HDL cholesterol (HDL) and triacylglycerols (TRG) concentration in blood were carried out, concentration of LDL cholesterol (LDL) was evaluated. Energy deficit was induced by a diet and “fat burning” type exercises. Leptin concentration in blood serum was significantly higher before (41.7±16.5 ng/ml) than after the accomplishment of experiment (24.7±16.2 ng/ml). Body mass decreased, which was mainly due to a drop in body fat (from 36.6±13.9 kg to 29.0±12.5 kg). All changes have been statistically significant at the level of P<0.001. A significant decrease of CHO (from 187.9±26.3 mg/dl to 167.1±25.4 mg/dl; P<0.001) and LDL (from 115.5±25.1 mg/dl to 102.3±21.5 mg/dl; P<0.05) concentration in blood was noticed. However, changes in HDL and TRG concentration were statistically insignificant. There was a statistically significant correlation (P<0.05) recorded between changes in leptin concentration in blood and changes in body mass, BMI and body fat (0.51; 0.58; 0.64 respectively). No correlation was observed between leptin and lean body mass, CHO, HDL, LDL or TRG

Developing a fully online course for senior medical students

In 2002 the University of Michigan Medical School created a one-month course in advanced medical therapeutics (AMT). All senior medical students were required to complete the course. To provide some flexibility for students who were interviewing for residency positions the AMT course was created using a distance-learning model, and in the 2008–2009 academic year it was offered in a fully online format. The components of the course are weekly case-based modules, a weekly online seminar, quizzes based on modules and seminars, and a research project based on a therapeutic question. The paper discusses the development and components of the AMT course, a survey of fourth-year medical students who participated in the course between 2007 and 2010, and how the course evolved over three years

Remote analysis of digitized x-ray image for bone injuries and other pathology.

This presentation was given at the Med-e-tel 2005 Conference in Luxembourg on April 7th, 2005.National Experiences in Telemedicine and eHealth: The purpose of the study was to evaluate the usefulness of new method (RODIA System) to monitor mineralization of the fracture gap on digitalized xray, osteolysis or loosening around orthopaedic implants or other bone pathology. Collection of radiographs of various orthopaedic pathologies was digitized for further analysis. Image Evaluation Module and Fracture Healing Monitor Module of Relative Optical Density Image Analysis (RODIA) System [1] were utilized for images evaluation. Search for subtle fracture line, assessment of the bone osteolysis around orthopaedic implants, and progress of bone tumour retrospective evaluation were performed with RODIA System. Developed Relative Optical De nsity Image Analysis System (RODIA System) allows remote analyzing and measure digitized X-ray image to reliably enhance of image evaluation.Department of Orthopedics and Traumatology of Locomotors System, Medical University; Center of Excellence 'TeleOrto'; Department of Anatomy, Center of Biostructure Research, Medical University all of Warsaw, Poland and SAS Institute European Headquarters, Heidelberg, German