Monument Unveiled in Puyallup

"On Friday afternoon, October 30, 1925, under the auspices of the Washington State Historical Society a monument was unveiled at the north end of the Meridian Street Bridge, Puyallup… A statement of the reasons for erecting the monument was made by W.P. Bonney, Secretary of the Washington State Historical Society as follows: ...'The inscriptions on these tablets are not news today. They hark back to the news items of seventy years ago; back to the days when John Carson, with his family, came and established his home on this spot.'

Lewis County's Early History

"W.P. Bonney, Secretary of the Washington State Historical Society, and one of the Contributing Editors of the Washington Historical Quarterly, furnishes a copy of the address he delivered at the dedicatory ceremonies of Lewis County's new courthouse at Chehalis on June 17, 1927. The address contains a brief and compact record of Lewis County's early history.

Puyallup Indian Reservation

"On December 26, the treaty was signed by Governor Stevens on behalf of the United States, by sixty-two Indians, Chiefs and head-men of the tribes named…Article 1 fo the treaty…

Naming Stampede Pass

"Forty years ago this spring I, with about forty others, tramped through a swampy forest, skirted the base of 'Enumclaw,' the mountain near your city, on our way to Green River, in the employ of the Northern Pacific Railroad Company…

Marking Historic Sites

"Mr. W.P. Bonney, who furnished this article, is Secretary of the Washington State Historical Society. He is entitled to the credit of suggesting and planning most of the markers mentioned.

Monument Unveiled in Puyallup

"On Friday afternoon, October 30, 1925, under the auspices of the Washington State Historical Society a monument was unveiled at the north end of the Meridian Street Bridge, Puyallup… A statement of the reasons for erecting the monument was made by W.P. Bonney, Secretary of the Washington State Historical Society as follows: ...'The inscriptions on these tablets are not news today. They hark back to the news items of seventy years ago; back to the days when John Carson, with his family, came and established his home on this spot.'

Lewis County's Early History

"W.P. Bonney, Secretary of the Washington State Historical Society, and one of the Contributing Editors of the Washington Historical Quarterly, furnishes a copy of the address he delivered at the dedicatory ceremonies of Lewis County's new courthouse at Chehalis on June 17, 1927. The address contains a brief and compact record of Lewis County's early history.

NMR-based metabolomics study of canine bladder cancer

AbstractBladder cancer is one of the leading lethal cancers worldwide. With the high risk of recurrence for bladder cancer following the initial diagnoses, lifelong monitoring of patients is necessary. The lack of adequate sensitivity and specificity of current noninvasive monitoring approaches including urine cytology, other urine tests, and imaging, underlines the importance of studies that focus on the detection of more reliable biomarkers for this cancer. The emerging area of metabolomics, which deals with the analysis of a large number of small molecules in a single step, promises immense potential for discovering metabolite markers for screening and monitoring treatment response and recurrence in patients with bladder cancer. Since naturally-occurring canine transitional cell carcinoma of the urinary bladder is very similar to human invasive bladder cancer, spontaneous canine transitional cell carcinoma has been applied as a relevant animal model of human invasive transitional cell carcinoma. In this study, we have focused on profiling the metabolites in urine from dogs with transitional cell carcinoma and healthy control dogs combining nuclear magnetic resonance spectroscopy and statistical analysis methods. 1H NMR-based metabolite profiling analysis was shown to be an effective approach for differentiating samples from dogs with transitional cell carcinoma and healthy controls based on a partial least square-discriminant analysis of the NMR spectra. In addition, there were significant differences in the levels of six individual metabolites between samples from dogs with transitional cell carcinoma and the control group based on the Student's t-test. These metabolites were selected to build a separate partial least square‐discriminant analysis model that was then used to test the classification accuracy. The result showed good classification between transitional cell carcinoma and control groups with the area under the receiver operating characteristic curve of 0.85. The sensitivity and specificity of the model were 86% and 78%, respectively. These results suggest that urine metabolic profiling may have potential for early detection of bladder cancer and of bladder cancer recurrence following treatment, and may enhance our understanding of the mechanisms involved